Standardize SE by switching from custom identifiers into gDR-default
Source:R/standardize_MAE.R
standardize_se.Rd
Standardize SE by switching from custom identifiers into gDR-default
Arguments
- se
a SummarizedExperiment object with drug-response data generate by gDR pipeline
- use_default
boolean indicating whether or not to use default identifiers for standardization
Examples
mae <- get_synthetic_data("finalMAE_small.qs")
se <- mae[[1]]
S4Vectors::metadata(se)$identifiers$drug <- "druug"
standardize_se(se)
#> class: SummarizedExperiment
#> dim: 10 10
#> metadata(5): identifiers experiment_metadata Keys fit_parameters
#> .internal
#> assays(5): RawTreated Controls Normalized Averaged Metrics
#> rownames(10): G00002_drug_002_moa_A_72 G00003_drug_003_moa_A_72 ...
#> G00010_drug_010_moa_A_72 G00011_drug_011_moa_B_72
#> rowData names(4): Gnumber DrugName drug_moa Duration
#> colnames(10): CL00011_cellline_BA_tissue_x_26
#> CL00012_cellline_CA_tissue_x_30 ... CL00019_cellline_JB_tissue_z_58
#> CL00020_cellline_KB_tissue_z_62
#> colData names(4): clid CellLineName Tissue ReferenceDivisionTime