Function to obtain data from gDRtestData and prepare for unit tests
Examples
get_testdata_combo()
#> $drug_names
#> [1] "drug_001" "drug_002" "drug_011" "drug_021" "drug_026" "drug_031"
#>
#> $cell_line_names
#> [1] "cellline_AA" "cellline_EA" "cellline_IB" "cellline_MC" "cellline_BC"
#> [6] "cellline_FD" "cellline_JE" "cellline_NE"
#>
#> $dt
#> Drug Name Cell Line Name rId
#> <char> <char> <char>
#> 1: drug_001 cellline_AA G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 2: drug_002 cellline_AA G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 3: drug_011 cellline_AA G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 4: drug_001 cellline_EA G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 5: drug_002 cellline_EA G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 6: drug_011 cellline_EA G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 7: drug_001 cellline_IB G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 8: drug_002 cellline_IB G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 9: drug_011 cellline_IB G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 10: drug_001 cellline_MC G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 11: drug_002 cellline_MC G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 12: drug_011 cellline_MC G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 13: drug_001 cellline_BC G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 14: drug_002 cellline_BC G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 15: drug_011 cellline_BC G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 16: drug_001 cellline_FD G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 17: drug_002 cellline_FD G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 18: drug_011 cellline_FD G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 19: drug_001 cellline_JE G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 20: drug_002 cellline_JE G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 21: drug_011 cellline_JE G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 22: drug_001 cellline_NE G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 23: drug_002 cellline_NE G00002_drug_002_moa_A_G00021_drug_021_moa_D_72
#> 24: drug_011 cellline_NE G00011_drug_011_moa_B_G00021_drug_021_moa_D_72
#> 25: drug_021 cellline_AA G00021_drug_021_moa_D_72
#> 26: drug_026 cellline_AA G00026_drug_026_moa_E_72
#> 27: drug_031 cellline_AA G00031_drug_031_moa_F_72
#> 28: drug_021 cellline_EA G00021_drug_021_moa_D_72
#> 29: drug_026 cellline_EA G00026_drug_026_moa_E_72
#> 30: drug_031 cellline_EA G00031_drug_031_moa_F_72
#> 31: drug_021 cellline_IB G00021_drug_021_moa_D_72
#> 32: drug_026 cellline_IB G00026_drug_026_moa_E_72
#> 33: drug_031 cellline_IB G00031_drug_031_moa_F_72
#> 34: drug_021 cellline_MC G00021_drug_021_moa_D_72
#> 35: drug_026 cellline_MC G00026_drug_026_moa_E_72
#> 36: drug_031 cellline_MC G00031_drug_031_moa_F_72
#> 37: drug_021 cellline_BC G00021_drug_021_moa_D_72
#> 38: drug_026 cellline_BC G00026_drug_026_moa_E_72
#> 39: drug_031 cellline_BC G00031_drug_031_moa_F_72
#> 40: drug_021 cellline_FD G00021_drug_021_moa_D_72
#> 41: drug_026 cellline_FD G00026_drug_026_moa_E_72
#> 42: drug_031 cellline_FD G00031_drug_031_moa_F_72
#> 43: drug_021 cellline_JE G00021_drug_021_moa_D_72
#> 44: drug_026 cellline_JE G00026_drug_026_moa_E_72
#> 45: drug_031 cellline_JE G00031_drug_031_moa_F_72
#> 46: drug_021 cellline_NE G00021_drug_021_moa_D_72
#> 47: drug_026 cellline_NE G00026_drug_026_moa_E_72
#> 48: drug_031 cellline_NE G00031_drug_031_moa_F_72
#> Drug Name Cell Line Name rId
#> cId EC50 x_AOC h RV
#> <char> <num> <num> <num>
#> 1: CL00010_cellline_AA_tissue_x_22 0.31359259 0.6864074074 0.6864074074
#> 2: CL00010_cellline_AA_tissue_x_22 0.46488148 0.5351185185 0.5351185185
#> 3: CL00010_cellline_AA_tissue_x_22 0.30005185 0.6999481481 0.6999481481
#> 4: CL00014_cellline_EA_tissue_x_38 0.54018519 0.4598148148 0.4598148148
#> 5: CL00014_cellline_EA_tissue_x_38 0.46981481 0.5301851852 0.5301851852
#> 6: CL00014_cellline_EA_tissue_x_38 -0.27716296 1.2771629630 1.2771629630
#> 7: CL00018_cellline_IB_tissue_y_54 -0.70610370 1.7061037037 1.7061037037
#> 8: CL00018_cellline_IB_tissue_y_54 -0.86958519 1.8695851852 1.8695851852
#> 9: CL00018_cellline_IB_tissue_y_54 -0.60236296 1.6023629630 1.6023629630
#> 10: CL00022_cellline_MC_tissue_z_70 -0.73374444 1.7337444444 1.7337444444
#> 11: CL00022_cellline_MC_tissue_z_70 -0.58530000 1.5853000000 1.5853000000
#> 12: CL00022_cellline_MC_tissue_z_70 -0.54707037 1.5470703704 1.5470703704
#> 13: CL00026_cellline_BC_tissue_w_26 -0.27410000 1.2741000000 1.2741000000
#> 14: CL00026_cellline_BC_tissue_w_26 0.19546296 0.8045370370 0.8045370370
#> 15: CL00026_cellline_BC_tissue_w_26 0.08634815 0.9136518519 0.9136518519
#> 16: CL00030_cellline_FD_tissue_w_42 -0.36797407 1.3679740741 1.3679740741
#> 17: CL00030_cellline_FD_tissue_w_42 -0.30042222 1.3004222222 1.3004222222
#> 18: CL00030_cellline_FD_tissue_w_42 -0.41170741 1.4117074074 1.4117074074
#> 19: CL00034_cellline_JE_tissue_w_58 -0.69018148 1.6901814815 1.6901814815
#> 20: CL00034_cellline_JE_tissue_w_58 -0.64542222 1.6454222222 1.6454222222
#> 21: CL00034_cellline_JE_tissue_w_58 -0.64786296 1.6478629630 1.6478629630
#> 22: CL00038_cellline_NE_tissue_w_74 -0.75242963 1.7524296296 1.7524296296
#> 23: CL00038_cellline_NE_tissue_w_74 -0.54112963 1.5411296296 1.5411296296
#> 24: CL00038_cellline_NE_tissue_w_74 -0.43574815 1.4357481481 1.4357481481
#> 25: CL00010_cellline_AA_tissue_x_22 0.99633210 0.0036679012 0.0036679012
#> 26: CL00010_cellline_AA_tissue_x_22 0.99605432 0.0039456790 0.0039456790
#> 27: CL00010_cellline_AA_tissue_x_22 0.99742531 0.0025746914 0.0025746914
#> 28: CL00014_cellline_EA_tissue_x_38 0.99882160 0.0011783951 0.0011783951
#> 29: CL00014_cellline_EA_tissue_x_38 1.00082469 -0.0008246914 -0.0008246914
#> 30: CL00014_cellline_EA_tissue_x_38 0.99524444 0.0047555556 0.0047555556
#> 31: CL00018_cellline_IB_tissue_y_54 0.99930432 0.0006956790 0.0006956790
#> 32: CL00018_cellline_IB_tissue_y_54 0.99741975 0.0025802469 0.0025802469
#> 33: CL00018_cellline_IB_tissue_y_54 0.99455556 0.0054444444 0.0054444444
#> 34: CL00022_cellline_MC_tissue_z_70 0.99650309 0.0034969136 0.0034969136
#> 35: CL00022_cellline_MC_tissue_z_70 1.00027901 -0.0002790123 -0.0002790123
#> 36: CL00022_cellline_MC_tissue_z_70 0.99801481 0.0019851852 0.0019851852
#> 37: CL00026_cellline_BC_tissue_w_26 0.99741235 0.0025876543 0.0025876543
#> 38: CL00026_cellline_BC_tissue_w_26 1.00112284 -0.0011228395 -0.0011228395
#> 39: CL00026_cellline_BC_tissue_w_26 0.99772222 0.0022777778 0.0022777778
#> 40: CL00030_cellline_FD_tissue_w_42 0.99697037 0.0030296296 0.0030296296
#> 41: CL00030_cellline_FD_tissue_w_42 1.00156420 -0.0015641975 -0.0015641975
#> 42: CL00030_cellline_FD_tissue_w_42 0.99700185 0.0029981481 0.0029981481
#> 43: CL00034_cellline_JE_tissue_w_58 1.00209074 -0.0020907407 -0.0020907407
#> 44: CL00034_cellline_JE_tissue_w_58 1.00434630 -0.0043462963 -0.0043462963
#> 45: CL00034_cellline_JE_tissue_w_58 1.00456852 -0.0045685185 -0.0045685185
#> 46: CL00038_cellline_NE_tissue_w_74 0.99237531 0.0076246914 0.0076246914
#> 47: CL00038_cellline_NE_tissue_w_74 0.99570370 0.0042962963 0.0042962963
#> 48: CL00038_cellline_NE_tissue_w_74 0.99102160 0.0089783951 0.0089783951
#> cId EC50 x_AOC h RV
#> GEC50 GR Max ec50 GR Inf GR 0 h GR E Inf p_value
#> <num> <num> <num> <num> <num> <num> <num> <num>
#> 1: -Inf 0.31106667 0 0.31359259 0.31359259 1e-04 0 1.0000000
#> 2: -Inf 0.44736667 0 0.46488148 0.46488148 1e-04 0 0.8071221
#> 3: -Inf 0.28696667 0 0.30005185 0.30005185 1e-04 0 0.8857690
#> 4: Inf 0.53176667 0 0.54018519 0.54018519 1e-04 0 0.9931766
#> 5: -Inf 0.45896667 0 0.46981481 0.46981481 1e-04 0 1.0000000
#> 6: -Inf -0.31976667 0 -0.27716296 -0.27716296 1e-04 0 0.7207726
#> 7: -Inf -0.72603333 0 -0.70610370 -0.70610370 1e-04 0 0.9103471
#> 8: -Inf -0.91793333 0 -0.86958519 -0.86958519 1e-04 0 1.0000000
#> 9: -Inf -0.61163333 0 -0.60236296 -0.60236296 1e-04 0 1.0000000
#> 10: -Inf -0.74943333 0 -0.73374444 -0.73374444 1e-04 0 0.5342941
#> 11: -Inf -0.60303333 0 -0.58530000 -0.58530000 1e-04 0 1.0000000
#> 12: -Inf -0.52776667 0 -0.54707037 -0.54707037 1e-04 0 1.0000000
#> 13: -Inf -0.26623333 0 -0.27410000 -0.27410000 1e-04 0 0.9488407
#> 14: -Inf 0.19010000 0 0.19546296 0.19546296 1e-04 0 1.0000000
#> 15: -Inf 0.08556667 0 0.08634815 0.08634815 1e-04 0 0.7266117
#> 16: -Inf -0.36960000 0 -0.36797407 -0.36797407 1e-04 0 1.0000000
#> 17: -Inf -0.28823333 0 -0.30042222 -0.30042222 1e-04 0 0.9333698
#> 18: -Inf -0.42910000 0 -0.41170741 -0.41170741 1e-04 0 0.9975568
#> 19: -Inf -0.70030000 0 -0.69018148 -0.69018148 1e-04 0 1.0000000
#> 20: -Inf -0.65620000 0 -0.64542222 -0.64542222 1e-04 0 0.2453094
#> 21: -Inf -0.64646667 0 -0.64786296 -0.64786296 1e-04 0 1.0000000
#> 22: -Inf -0.77066667 0 -0.75242963 -0.75242963 1e-04 0 0.8325653
#> 23: -Inf -0.54173333 0 -0.54112963 -0.54112963 1e-04 0 1.0000000
#> 24: -Inf -0.43120000 0 -0.43574815 -0.43574815 1e-04 0 0.3266012
#> 25: Inf 0.98825556 0 0.99633210 0.99633210 1e-04 0 0.9083469
#> 26: Inf 0.98951667 0 0.99605432 0.99605432 1e-04 0 0.5747625
#> 27: Inf 0.99997222 0 0.99742531 0.99742531 1e-04 0 1.0000000
#> 28: Inf 1.00171111 0 0.99882160 0.99882160 1e-04 0 1.0000000
#> 29: Inf 0.99019444 0 1.00082469 1.00082469 1e-04 0 1.0000000
#> 30: Inf 0.98635000 0 0.99524444 0.99524444 1e-04 0 0.7599590
#> 31: Inf 0.99443333 0 0.99930432 0.99930432 1e-04 0 1.0000000
#> 32: Inf 0.98379444 0 0.99741975 0.99741975 1e-04 0 0.8885349
#> 33: Inf 0.99092222 0 0.99455556 0.99455556 1e-04 0 0.8825499
#> 34: Inf 0.99152778 0 0.99650309 0.99650309 1e-04 0 0.8933194
#> 35: Inf 1.00274444 0 1.00027901 1.00027901 1e-04 0 1.0000000
#> 36: Inf 0.99694444 0 0.99801481 0.99801481 1e-04 0 1.0000000
#> 37: Inf 0.99417222 0 0.99741235 0.99741235 1e-04 0 1.0000000
#> 38: Inf 0.99040000 0 1.00112284 1.00112284 1e-04 0 1.0000000
#> 39: Inf 0.98581667 0 0.99772222 0.99772222 1e-04 0 1.0000000
#> 40: Inf 0.99617778 0 0.99697037 0.99697037 1e-04 0 0.9235286
#> 41: Inf 0.99464444 0 1.00156420 1.00156420 1e-04 0 1.0000000
#> 42: Inf 0.99352222 0 0.99700185 0.99700185 1e-04 0 1.0000000
#> 43: Inf 0.99495556 0 1.00209074 1.00209074 1e-04 0 1.0000000
#> 44: Inf 0.99893889 0 1.00434630 1.00434630 1e-04 0 1.0000000
#> 45: Inf 0.99412222 0 1.00456852 1.00456852 1e-04 0 1.0000000
#> 46: Inf 0.98193889 0 0.99237531 0.99237531 1e-04 0 0.9470593
#> 47: Inf 0.99475000 0 0.99570370 0.99570370 1e-04 0 1.0000000
#> 48: Inf 0.98178889 0 0.99102160 0.99102160 1e-04 0 0.5022123
#> GEC50 GR Max ec50 GR Inf GR 0 h GR E Inf p_value
#> rss E0 fit_type Concentration N_conc
#> <num> <num> <char> <num> <int>
#> 1: 0.0008866115 0.01649918 DRCConstantFitResult 1 9
#> 2: 0.0004315725 0.01839689 DRCConstantFitResult 1 9
#> 3: 0.0007135742 0.02138625 DRCConstantFitResult 1 9
#> 4: 0.0012209428 0.02595851 DRCConstantFitResult 1 9
#> 5: 0.0022302917 0.02747480 DRCConstantFitResult 1 9
#> 6: 0.0113145908 0.03277132 DRCConstantFitResult 1 9
#> 7: 0.0033764235 0.02448461 DRCConstantFitResult 1 9
#> 8: 0.0078975847 0.03212551 DRCConstantFitResult 1 9
#> 9: 0.0007231072 0.02728644 DRCConstantFitResult 1 9
#> 10: 0.0027121533 0.02315973 DRCConstantFitResult 1 9
#> 11: 0.0016184375 0.01779364 DRCConstantFitResult 1 9
#> 12: 0.0018844868 0.02788363 DRCConstantFitResult 1 9
#> 13: 0.0034670347 0.04144568 DRCConstantFitResult 1 9
#> 14: 0.0063340983 0.01543815 DRCConstantFitResult 1 9
#> 15: 0.0014072769 0.01812046 DRCConstantFitResult 1 9
#> 16: 0.0007678705 0.02714955 DRCConstantFitResult 1 9
#> 17: 0.0012846424 0.01975923 DRCConstantFitResult 1 9
#> 18: 0.0027127052 0.03229288 DRCConstantFitResult 1 9
#> 19: 0.0009149403 0.01314100 DRCConstantFitResult 1 9
#> 20: 0.0003673962 0.01333922 DRCConstantFitResult 1 9
#> 21: 0.0001904803 0.01667500 DRCConstantFitResult 1 9
#> 22: 0.0017873127 0.02152308 DRCConstantFitResult 1 9
#> 23: 0.0015366333 0.02457477 DRCConstantFitResult 1 9
#> 24: 0.0009474410 0.01680536 DRCConstantFitResult 1 9
#> 25: 0.0001913761 0.02746480 DRCConstantFitResult 1 9
#> 26: 0.0003942057 0.02873235 DRCConstantFitResult 1 9
#> 27: 0.0002641617 0.02824695 DRCConstantFitResult 1 9
#> 28: 0.0001847002 0.02798887 DRCConstantFitResult 1 9
#> 29: 0.0003173711 0.02860886 DRCConstantFitResult 1 9
#> 30: 0.0004066196 0.02893784 DRCConstantFitResult 1 9
#> 31: 0.0002318267 0.02974214 DRCConstantFitResult 1 9
#> 32: 0.0006522847 0.02977052 DRCConstantFitResult 1 9
#> 33: 0.0002597482 0.02978818 DRCConstantFitResult 1 9
#> 34: 0.0009760935 0.02804300 DRCConstantFitResult 1 9
#> 35: 0.0003425882 0.02895447 DRCConstantFitResult 1 9
#> 36: 0.0001608500 0.02855131 DRCConstantFitResult 1 9
#> 37: 0.0003994238 0.02823440 DRCConstantFitResult 1 9
#> 38: 0.0003875042 0.02856573 DRCConstantFitResult 1 9
#> 39: 0.0009228802 0.02889972 DRCConstantFitResult 1 9
#> 40: 0.0004802806 0.03010221 DRCConstantFitResult 1 9
#> 41: 0.0002059010 0.03105234 DRCConstantFitResult 1 9
#> 42: 0.0002710891 0.02977945 DRCConstantFitResult 1 9
#> 43: 0.0007010440 0.02881507 DRCConstantFitResult 1 9
#> 44: 0.0004884894 0.02909892 DRCConstantFitResult 1 9
#> 45: 0.0005460898 0.02845883 DRCConstantFitResult 1 9
#> 46: 0.0005124332 0.02799662 DRCConstantFitResult 1 9
#> 47: 0.0004795990 0.02781475 DRCConstantFitResult 1 9
#> 48: 0.0002233779 0.02960396 DRCConstantFitResult 1 9
#> rss E0 fit_type Concentration N_conc
#> normalization_type fit_source cotrt_value ratio source Gnumber
#> <char> <char> <num> <num> <char> <char>
#> 1: RV gDR 3.160 NA row_fittings G00001
#> 2: RV gDR 3.160 NA row_fittings G00002
#> 3: RV gDR 10.000 NA row_fittings G00011
#> 4: GR gDR 1.000 NA row_fittings G00001
#> 5: GR gDR 0.316 NA row_fittings G00002
#> 6: GR gDR 3.160 NA row_fittings G00011
#> 7: GR gDR 10.000 NA row_fittings G00001
#> 8: GR gDR 3.160 NA row_fittings G00002
#> 9: GR gDR 3.160 NA row_fittings G00011
#> 10: GR gDR 10.000 NA row_fittings G00001
#> 11: GR gDR 0.316 NA row_fittings G00002
#> 12: GR gDR 1.000 NA row_fittings G00011
#> 13: GR gDR 10.000 NA row_fittings G00001
#> 14: GR gDR 10.000 NA row_fittings G00002
#> 15: GR gDR 10.000 NA row_fittings G00011
#> 16: GR gDR 10.000 NA row_fittings G00001
#> 17: GR gDR 10.000 NA row_fittings G00002
#> 18: GR gDR 10.000 NA row_fittings G00011
#> 19: GR gDR 10.000 NA row_fittings G00001
#> 20: GR gDR 10.000 NA row_fittings G00002
#> 21: GR gDR 10.000 NA row_fittings G00011
#> 22: GR gDR 3.160 NA row_fittings G00001
#> 23: GR gDR 3.160 NA row_fittings G00002
#> 24: GR gDR 10.000 NA row_fittings G00011
#> 25: RV gDR NA NA <NA> G00021
#> 26: RV gDR NA NA <NA> G00026
#> 27: RV gDR NA NA <NA> G00031
#> 28: RV gDR NA NA <NA> G00021
#> 29: RV gDR NA NA <NA> G00026
#> 30: RV gDR NA NA <NA> G00031
#> 31: RV gDR NA NA <NA> G00021
#> 32: RV gDR NA NA <NA> G00026
#> 33: RV gDR NA NA <NA> G00031
#> 34: RV gDR NA NA <NA> G00021
#> 35: RV gDR NA NA <NA> G00026
#> 36: RV gDR NA NA <NA> G00031
#> 37: RV gDR NA NA <NA> G00021
#> 38: RV gDR NA NA <NA> G00026
#> 39: RV gDR NA NA <NA> G00031
#> 40: RV gDR NA NA <NA> G00021
#> 41: RV gDR NA NA <NA> G00026
#> 42: RV gDR NA NA <NA> G00031
#> 43: RV gDR NA NA <NA> G00021
#> 44: RV gDR NA NA <NA> G00026
#> 45: RV gDR NA NA <NA> G00031
#> 46: RV gDR NA NA <NA> G00021
#> 47: RV gDR NA NA <NA> G00026
#> 48: RV gDR NA NA <NA> G00031
#> normalization_type fit_source cotrt_value ratio source Gnumber
#> Drug MOA Gnumber_2 Drug Name 2 Drug MOA2 Duration clid Tissue
#> <char> <char> <char> <char> <num> <char> <char>
#> 1: moa_A G00021 drug_021 moa_D 72 CL00010 tissue_x
#> 2: moa_A G00021 drug_021 moa_D 72 CL00010 tissue_x
#> 3: moa_B G00021 drug_021 moa_D 72 CL00010 tissue_x
#> 4: moa_A G00021 drug_021 moa_D 72 CL00014 tissue_x
#> 5: moa_A G00021 drug_021 moa_D 72 CL00014 tissue_x
#> 6: moa_B G00021 drug_021 moa_D 72 CL00014 tissue_x
#> 7: moa_A G00021 drug_021 moa_D 72 CL00018 tissue_y
#> 8: moa_A G00021 drug_021 moa_D 72 CL00018 tissue_y
#> 9: moa_B G00021 drug_021 moa_D 72 CL00018 tissue_y
#> 10: moa_A G00021 drug_021 moa_D 72 CL00022 tissue_z
#> 11: moa_A G00021 drug_021 moa_D 72 CL00022 tissue_z
#> 12: moa_B G00021 drug_021 moa_D 72 CL00022 tissue_z
#> 13: moa_A G00021 drug_021 moa_D 72 CL00026 tissue_w
#> 14: moa_A G00021 drug_021 moa_D 72 CL00026 tissue_w
#> 15: moa_B G00021 drug_021 moa_D 72 CL00026 tissue_w
#> 16: moa_A G00021 drug_021 moa_D 72 CL00030 tissue_w
#> 17: moa_A G00021 drug_021 moa_D 72 CL00030 tissue_w
#> 18: moa_B G00021 drug_021 moa_D 72 CL00030 tissue_w
#> 19: moa_A G00021 drug_021 moa_D 72 CL00034 tissue_w
#> 20: moa_A G00021 drug_021 moa_D 72 CL00034 tissue_w
#> 21: moa_B G00021 drug_021 moa_D 72 CL00034 tissue_w
#> 22: moa_A G00021 drug_021 moa_D 72 CL00038 tissue_w
#> 23: moa_A G00021 drug_021 moa_D 72 CL00038 tissue_w
#> 24: moa_B G00021 drug_021 moa_D 72 CL00038 tissue_w
#> 25: moa_D <NA> <NA> <NA> 72 CL00010 tissue_x
#> 26: moa_E <NA> <NA> <NA> 72 CL00010 tissue_x
#> 27: moa_F <NA> <NA> <NA> 72 CL00010 tissue_x
#> 28: moa_D <NA> <NA> <NA> 72 CL00014 tissue_x
#> 29: moa_E <NA> <NA> <NA> 72 CL00014 tissue_x
#> 30: moa_F <NA> <NA> <NA> 72 CL00014 tissue_x
#> 31: moa_D <NA> <NA> <NA> 72 CL00018 tissue_y
#> 32: moa_E <NA> <NA> <NA> 72 CL00018 tissue_y
#> 33: moa_F <NA> <NA> <NA> 72 CL00018 tissue_y
#> 34: moa_D <NA> <NA> <NA> 72 CL00022 tissue_z
#> 35: moa_E <NA> <NA> <NA> 72 CL00022 tissue_z
#> 36: moa_F <NA> <NA> <NA> 72 CL00022 tissue_z
#> 37: moa_D <NA> <NA> <NA> 72 CL00026 tissue_w
#> 38: moa_E <NA> <NA> <NA> 72 CL00026 tissue_w
#> 39: moa_F <NA> <NA> <NA> 72 CL00026 tissue_w
#> 40: moa_D <NA> <NA> <NA> 72 CL00030 tissue_w
#> 41: moa_E <NA> <NA> <NA> 72 CL00030 tissue_w
#> 42: moa_F <NA> <NA> <NA> 72 CL00030 tissue_w
#> 43: moa_D <NA> <NA> <NA> 72 CL00034 tissue_w
#> 44: moa_E <NA> <NA> <NA> 72 CL00034 tissue_w
#> 45: moa_F <NA> <NA> <NA> 72 CL00034 tissue_w
#> 46: moa_D <NA> <NA> <NA> 72 CL00038 tissue_w
#> 47: moa_E <NA> <NA> <NA> 72 CL00038 tissue_w
#> 48: moa_F <NA> <NA> <NA> 72 CL00038 tissue_w
#> Drug MOA Gnumber_2 Drug Name 2 Drug MOA2 Duration clid Tissue
#> ReferenceDivisionTime GR50 IC50 E Max GR value
#> <num> <num> <num> <num> <num>
#> 1: 22 0.31359259 0.31359259 0.31359259 0.31359259
#> 2: 22 0.46488148 0.46488148 0.46488148 0.46488148
#> 3: 22 0.30005185 0.30005185 0.30005185 0.30005185
#> 4: 38 0.54018519 0.54018519 0.54018519 0.54018519
#> 5: 38 0.46981481 0.46981481 0.46981481 0.46981481
#> 6: 38 -0.27716296 -0.27716296 -0.27716296 -0.27716296
#> 7: 54 -0.70610370 -0.70610370 -0.70610370 -0.70610370
#> 8: 54 -0.86958519 -0.86958519 -0.86958519 -0.86958519
#> 9: 54 -0.60236296 -0.60236296 -0.60236296 -0.60236296
#> 10: 70 -0.73374444 -0.73374444 -0.73374444 -0.73374444
#> 11: 70 -0.58530000 -0.58530000 -0.58530000 -0.58530000
#> 12: 70 -0.54707037 -0.54707037 -0.54707037 -0.54707037
#> 13: 26 -0.27410000 -0.27410000 -0.27410000 -0.27410000
#> 14: 26 0.19546296 0.19546296 0.19546296 0.19546296
#> 15: 26 0.08634815 0.08634815 0.08634815 0.08634815
#> 16: 42 -0.36797407 -0.36797407 -0.36797407 -0.36797407
#> 17: 42 -0.30042222 -0.30042222 -0.30042222 -0.30042222
#> 18: 42 -0.41170741 -0.41170741 -0.41170741 -0.41170741
#> 19: 58 -0.69018148 -0.69018148 -0.69018148 -0.69018148
#> 20: 58 -0.64542222 -0.64542222 -0.64542222 -0.64542222
#> 21: 58 -0.64786296 -0.64786296 -0.64786296 -0.64786296
#> 22: 74 -0.75242963 -0.75242963 -0.75242963 -0.75242963
#> 23: 74 -0.54112963 -0.54112963 -0.54112963 -0.54112963
#> 24: 74 -0.43574815 -0.43574815 -0.43574815 -0.43574815
#> 25: 22 0.99633210 0.99633210 0.99633210 0.99633210
#> 26: 22 0.99605432 0.99605432 0.99605432 0.99605432
#> 27: 22 0.99742531 0.99742531 0.99742531 0.99742531
#> 28: 38 0.99882160 0.99882160 0.99882160 0.99882160
#> 29: 38 1.00082469 1.00082469 1.00082469 1.00082469
#> 30: 38 0.99524444 0.99524444 0.99524444 0.99524444
#> 31: 54 0.99930432 0.99930432 0.99930432 0.99930432
#> 32: 54 0.99741975 0.99741975 0.99741975 0.99741975
#> 33: 54 0.99455556 0.99455556 0.99455556 0.99455556
#> 34: 70 0.99650309 0.99650309 0.99650309 0.99650309
#> 35: 70 1.00027901 1.00027901 1.00027901 1.00027901
#> 36: 70 0.99801481 0.99801481 0.99801481 0.99801481
#> 37: 26 0.99741235 0.99741235 0.99741235 0.99741235
#> 38: 26 1.00112284 1.00112284 1.00112284 1.00112284
#> 39: 26 0.99772222 0.99772222 0.99772222 0.99772222
#> 40: 42 0.99697037 0.99697037 0.99697037 0.99697037
#> 41: 42 1.00156420 1.00156420 1.00156420 1.00156420
#> 42: 42 0.99700185 0.99700185 0.99700185 0.99700185
#> 43: 58 1.00209074 1.00209074 1.00209074 1.00209074
#> 44: 58 1.00434630 1.00434630 1.00434630 1.00434630
#> 45: 58 1.00456852 1.00456852 1.00456852 1.00456852
#> 46: 74 0.99237531 0.99237531 0.99237531 0.99237531
#> 47: 74 0.99570370 0.99570370 0.99570370 0.99570370
#> 48: 74 0.99102160 0.99102160 0.99102160 0.99102160
#> ReferenceDivisionTime GR50 IC50 E Max GR value
#>
#> $raw_data
#> rId
#> <char>
#> 1: G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 2: G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 3: G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 4: G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> 5: G00001_drug_001_moa_A_G00021_drug_021_moa_D_72
#> ---
#> 4268: G00021_drug_021_moa_D_72
#> 4269: G00026_drug_026_moa_E_72
#> 4270: G00026_drug_026_moa_E_72
#> 4271: G00031_drug_031_moa_F_72
#> 4272: G00031_drug_031_moa_F_72
#> cId x_mean x_AOC x_AOC_range xc50
#> <char> <num> <num> <num> <num>
#> 1: CL00010_cellline_AA_tissue_x_22 0.3135926 0.686407407 0.686407407 -Inf
#> 2: CL00010_cellline_AA_tissue_x_22 0.3142704 0.685729630 0.685729630 -Inf
#> 3: CL00010_cellline_AA_tissue_x_22 0.3148000 0.685200000 0.685200000 -Inf
#> 4: CL00010_cellline_AA_tissue_x_22 0.3158481 0.684151852 0.684151852 -Inf
#> 5: CL00010_cellline_AA_tissue_x_22 0.3323388 0.667661219 0.601409743 -Inf
#> ---
#> 4268: CL00038_cellline_NE_tissue_w_74 0.9843549 0.015645062 0.015645062 Inf
#> 4269: CL00038_cellline_NE_tissue_w_74 0.9957037 0.004296296 0.004296296 Inf
#> 4270: CL00038_cellline_NE_tissue_w_74 0.9911914 0.008808642 0.008808642 Inf
#> 4271: CL00038_cellline_NE_tissue_w_74 0.9910216 0.008978395 0.008978395 Inf
#> 4272: CL00038_cellline_NE_tissue_w_74 0.9815704 0.018429630 0.018429630 Inf
#> x_max ec50 x_inf x_0 h r2 p_value
#> <num> <num> <num> <num> <num> <num> <num>
#> 1: 0.3110667 0.0000 0.3135926 0.3135926 0.0001000 0.000000 1.00000000
#> 2: 0.2997000 0.0000 0.3142704 0.3142704 0.0001000 0.000000 0.09012268
#> 3: 0.3055667 0.0000 0.3148000 0.3148000 0.0001000 0.000000 0.48014356
#> 4: 0.3068667 0.0000 0.3158481 0.3158481 0.0001000 0.000000 0.59634451
#> 5: 0.2999333 0.0101 0.0000000 1.0000000 0.1530207 -9.123791 1.00000000
#> ---
#> 4268: 0.9629056 0.0000 0.9843549 0.9843549 0.0001000 0.000000 0.95421110
#> 4269: 0.9947500 0.0000 0.9957037 0.9957037 0.0001000 0.000000 1.00000000
#> 4270: 0.9892333 0.0000 0.9911914 0.9911914 0.0001000 0.000000 1.00000000
#> 4271: 0.9817889 0.0000 0.9910216 0.9910216 0.0001000 0.000000 0.50221225
#> 4272: 0.9625889 0.0000 0.9815704 0.9815704 0.0001000 0.000000 0.49077639
#> rss x_sd_avg fit_type maxlog10Concentration
#> <num> <num> <char> <num>
#> 1: 0.0008866115 0.01649918 DRCConstantFitResult 1.000000
#> 2: 0.0003075320 0.02110240 DRCConstantFitResult 1.000000
#> 3: 0.0003981517 0.01675435 DRCConstantFitResult 1.000000
#> 4: 0.0008042315 0.01691745 DRCConstantFitResult 1.000000
#> 5: 0.0117634036 0.01551077 DRC3pHillFitModelFixS0 1.004321
#> ---
#> 4268: 0.0021689801 0.05753726 DRCConstantFitResult 1.000000
#> 4269: 0.0004795990 0.02781475 DRCConstantFitResult 1.000000
#> 4270: 0.0021142487 0.05716746 DRCConstantFitResult 1.000000
#> 4271: 0.0002233779 0.02960396 DRCConstantFitResult 1.000000
#> 4272: 0.0009375695 0.06084279 DRCConstantFitResult 1.000000
#> N_conc normalization_type fit_source cotrt_value ratio
#> <int> <char> <char> <num> <num>
#> 1: 9 RV gDR 3.160 NA
#> 2: 9 RV gDR 10.000 NA
#> 3: 9 RV gDR 0.316 NA
#> 4: 9 RV gDR 1.000 NA
#> 5: 5 RV gDR NA 0.01
#> ---
#> 4268: 9 GR gDR NA NA
#> 4269: 9 RV gDR NA NA
#> 4270: 9 GR gDR NA NA
#> 4271: 9 RV gDR NA NA
#> 4272: 9 GR gDR NA NA
#> source Gnumber DrugName drug_moa Gnumber_2 DrugName_2
#> <char> <char> <char> <char> <char> <char>
#> 1: row_fittings G00001 drug_001 moa_A G00021 drug_021
#> 2: row_fittings G00001 drug_001 moa_A G00021 drug_021
#> 3: row_fittings G00001 drug_001 moa_A G00021 drug_021
#> 4: row_fittings G00001 drug_001 moa_A G00021 drug_021
#> 5: codilution_fittings G00001 drug_001 moa_A G00021 drug_021
#> ---
#> 4268: <NA> G00021 drug_021 moa_D <NA> <NA>
#> 4269: <NA> G00026 drug_026 moa_E <NA> <NA>
#> 4270: <NA> G00026 drug_026 moa_E <NA> <NA>
#> 4271: <NA> G00031 drug_031 moa_F <NA> <NA>
#> 4272: <NA> G00031 drug_031 moa_F <NA> <NA>
#> drug_moa_2 Duration clid CellLineName Tissue ReferenceDivisionTime
#> <char> <num> <char> <char> <char> <num>
#> 1: moa_D 72 CL00010 cellline_AA tissue_x 22
#> 2: moa_D 72 CL00010 cellline_AA tissue_x 22
#> 3: moa_D 72 CL00010 cellline_AA tissue_x 22
#> 4: moa_D 72 CL00010 cellline_AA tissue_x 22
#> 5: moa_D 72 CL00010 cellline_AA tissue_x 22
#> ---
#> 4268: <NA> 72 CL00038 cellline_NE tissue_w 74
#> 4269: <NA> 72 CL00038 cellline_NE tissue_w 74
#> 4270: <NA> 72 CL00038 cellline_NE tissue_w 74
#> 4271: <NA> 72 CL00038 cellline_NE tissue_w 74
#> 4272: <NA> 72 CL00038 cellline_NE tissue_w 74
#>