Convert a SummarizedExperiment assay to a long data.table and conduct some post processing steps
Source:R/convert_mae_se_assay_to_dt.R
convert_se_assay_to_custom_dt.Rd
Convert an assay within a SummarizedExperiment object to a long data.table. Then condcut some post processing steps.
Arguments
- se
A SummarizedExperiment object holding raw and/or processed dose-response data in its assays.
- assay_name
String of name of the assay to transform within the
se
.- output_table
String of type name of the output data.table
Details
Current strategy is per-assay specific.
combo assays: conversion to data.table only (with
wide_structure
= FALSE)'Metrics' assay can be converted to three types of outputs:
Metrics_initial (conversion to data.table only, with
wide_structure
= FALSE)Metrics_raw: same as Metrics_initial followed by:
fix for 'EC50' and 'Metrics_rownames'
flatten
prettifying and dropping excess variables
Metrics (same as Metrics_raw + capVals)
'Normalization' and 'Averaged' assay:
conversion to data.table (with
wide_structure
= TRUE)prettifying and dropping excess variables
NOTE: to extract information about 'Control' data, simply call the
function with the name of the assay holding data on controls.
To extract the reference data in to same format as 'Averaged' use convert_se_ref_assay_to_dt
.
Examples
mae <- get_synthetic_data("finalMAE_small")
se <- mae[[1]]
convert_se_assay_to_custom_dt(se, "Metrics")
#> r Id c Id GR Mean
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.472929759
#> 2: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.393219859
#> 3: G00004_drug_004_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.839327136
#> 4: G00005_drug_005_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.781708106
#> 5: G00006_drug_006_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.646759184
#> 6: G00007_drug_007_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.937436799
#> 7: G00008_drug_008_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.720542898
#> 8: G00009_drug_009_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.704849585
#> 9: G00010_drug_010_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.860814168
#> 10: G00011_drug_011_moa_B_72 CL00011_cellline_BA_tissue_x_26 0.207159460
#> 11: G00002_drug_002_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.710189522
#> 12: G00003_drug_003_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.332747901
#> 13: G00004_drug_004_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.922099383
#> 14: G00005_drug_005_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.808309237
#> 15: G00006_drug_006_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.866903473
#> 16: G00007_drug_007_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.836985050
#> 17: G00008_drug_008_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.791435957
#> 18: G00009_drug_009_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.491313620
#> 19: G00010_drug_010_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.763749516
#> 20: G00011_drug_011_moa_B_72 CL00012_cellline_CA_tissue_x_30 0.780650008
#> 21: G00002_drug_002_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.794248968
#> 22: G00003_drug_003_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.374827861
#> 23: G00004_drug_004_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.709167535
#> 24: G00005_drug_005_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.697104582
#> 25: G00006_drug_006_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.676875616
#> 26: G00007_drug_007_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.652414714
#> 27: G00008_drug_008_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.984385185
#> 28: G00009_drug_009_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.514432888
#> 29: G00010_drug_010_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.878482510
#> 30: G00011_drug_011_moa_B_72 CL00013_cellline_DA_tissue_x_34 0.634715550
#> 31: G00002_drug_002_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.858014876
#> 32: G00003_drug_003_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.909591493
#> 33: G00004_drug_004_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.864237280
#> 34: G00005_drug_005_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.939294715
#> 35: G00006_drug_006_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.669107225
#> 36: G00007_drug_007_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.876104175
#> 37: G00008_drug_008_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.987433333
#> 38: G00009_drug_009_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.752739905
#> 39: G00010_drug_010_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.857326327
#> 40: G00011_drug_011_moa_B_72 CL00014_cellline_EA_tissue_x_38 0.435872637
#> 41: G00002_drug_002_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.280017800
#> 42: G00003_drug_003_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.536315316
#> 43: G00004_drug_004_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.097480450
#> 44: G00005_drug_005_moa_A_72 CL00015_cellline_FA_tissue_x_42 -0.038391125
#> 45: G00006_drug_006_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.801673120
#> 46: G00007_drug_007_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.459163515
#> 47: G00008_drug_008_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.261931402
#> 48: G00009_drug_009_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.694250375
#> 49: G00010_drug_010_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.800908530
#> 50: G00011_drug_011_moa_B_72 CL00015_cellline_FA_tissue_x_42 -0.288561464
#> 51: G00002_drug_002_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.645509596
#> 52: G00003_drug_003_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.151209620
#> 53: G00004_drug_004_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.362400138
#> 54: G00005_drug_005_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.328454740
#> 55: G00006_drug_006_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.224809588
#> 56: G00007_drug_007_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.260281000
#> 57: G00008_drug_008_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.314141961
#> 58: G00009_drug_009_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.188230693
#> 59: G00010_drug_010_moa_A_72 CL00016_cellline_GB_tissue_y_46 0.177463519
#> 60: G00011_drug_011_moa_B_72 CL00016_cellline_GB_tissue_y_46 0.499202800
#> 61: G00002_drug_002_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.059329643
#> 62: G00003_drug_003_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.156760855
#> 63: G00004_drug_004_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.218107316
#> 64: G00005_drug_005_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.017982323
#> 65: G00006_drug_006_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.264938349
#> 66: G00007_drug_007_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.305037682
#> 67: G00008_drug_008_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.212954966
#> 68: G00009_drug_009_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.091984103
#> 69: G00010_drug_010_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.089668620
#> 70: G00011_drug_011_moa_B_72 CL00017_cellline_HB_tissue_y_50 0.334329487
#> 71: G00002_drug_002_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.501402843
#> 72: G00003_drug_003_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.077780973
#> 73: G00004_drug_004_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.131760019
#> 74: G00005_drug_005_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.093988826
#> 75: G00006_drug_006_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.125734009
#> 76: G00007_drug_007_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.003190178
#> 77: G00008_drug_008_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.286159124
#> 78: G00009_drug_009_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.112201368
#> 79: G00010_drug_010_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.005980476
#> 80: G00011_drug_011_moa_B_72 CL00018_cellline_IB_tissue_y_54 0.267043249
#> 81: G00002_drug_002_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.606827931
#> 82: G00003_drug_003_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.630511020
#> 83: G00004_drug_004_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.483973989
#> 84: G00005_drug_005_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.581204001
#> 85: G00006_drug_006_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.731518966
#> 86: G00007_drug_007_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.639612759
#> 87: G00008_drug_008_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.774175841
#> 88: G00009_drug_009_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.595786753
#> 89: G00010_drug_010_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.744384655
#> 90: G00011_drug_011_moa_B_72 CL00019_cellline_JB_tissue_z_58 0.449758703
#> 91: G00002_drug_002_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.418086223
#> 92: G00003_drug_003_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.203645096
#> 93: G00004_drug_004_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.132168662
#> 94: G00005_drug_005_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.024941265
#> 95: G00006_drug_006_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.249504542
#> 96: G00007_drug_007_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.176988967
#> 97: G00008_drug_008_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.264481101
#> 98: G00009_drug_009_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.077484203
#> 99: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.199150357
#> 100: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 -0.114813416
#> r Id c Id GR Mean
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> <num> <num> <num> <num> <num>
#> 1: 0.52707024 0.60484720 0.008956223 0.33660000 0.004512560
#> 2: 0.60678014 0.70277140 0.006591468 0.25136667 0.004714084
#> 3: 0.16067286 0.19050089 30.000000000 0.76383333 0.017152797
#> 4: 0.21829189 0.25018175 30.000000000 0.73936667 0.003425139
#> 5: 0.35324082 0.41393595 30.000000000 0.56643333 0.004372707
#> 6: 0.06256320 0.06575521 30.000000000 0.89593333 6.055622159
#> 7: 0.27945710 0.30997686 30.000000000 0.65743333 0.002559558
#> 8: 0.29515042 0.34870740 30.000000000 0.63046667 0.008778928
#> 9: 0.13918583 0.16273320 30.000000000 0.77656667 0.032779888
#> 10: 0.79284054 0.93195933 0.021403060 -0.24116667 0.025129204
#> 11: 0.28981048 0.33967455 30.000000000 0.65893333 0.005025942
#> 12: 0.66725210 0.76169198 0.003994252 0.17163333 0.003302060
#> 13: 0.07790062 0.09343051 30.000000000 0.88726667 0.008287858
#> 14: 0.19169076 0.22105147 30.000000000 0.79443333 0.003408721
#> 15: 0.13309653 0.15708142 30.000000000 0.82726667 0.008098714
#> 16: 0.16301495 0.18647466 30.000000000 0.79136667 0.003969114
#> 17: 0.20856404 0.24449577 30.000000000 0.67090000 0.027533368
#> 18: 0.50868638 0.60551778 0.014718394 0.30453333 0.010370991
#> 19: 0.23625048 0.28073456 30.000000000 0.67690000 0.011214419
#> 20: 0.21934999 0.26078562 30.000000000 0.70800000 0.008628168
#> 21: 0.20575103 0.24291610 30.000000000 0.68636667 0.018792763
#> 22: 0.62517214 0.72107940 0.004733541 0.24863333 0.003733333
#> 23: 0.29083246 0.34315973 30.000000000 0.57196667 0.019154852
#> 24: 0.30289542 0.35827349 30.000000000 0.56803333 0.015397125
#> 25: 0.32312438 0.38472189 30.000000000 0.57023333 0.007742051
#> 26: 0.34758529 0.41267609 30.000000000 0.50863333 0.011835446
#> 27: 0.01561481 0.01561481 30.000000000 0.97146667 0.000000000
#> 28: 0.48556711 0.56936523 0.034901667 0.22980000 0.022820133
#> 29: 0.12151749 0.14271246 30.000000000 0.82306667 0.024473312
#> 30: 0.36528445 0.43067820 30.000000000 0.51870000 0.007550572
#> 31: 0.14198512 0.16878024 30.000000000 0.80660000 0.007501824
#> 32: 0.09040851 0.10536618 30.000000000 0.82636667 0.038864061
#> 33: 0.13576272 0.15824641 30.000000000 0.76243333 0.038650933
#> 34: 0.06070529 0.07176469 30.000000000 0.91113333 0.020890672
#> 35: 0.33089278 0.39183474 30.000000000 0.59120000 0.005647023
#> 36: 0.12389583 0.14638273 30.000000000 0.78433333 0.021030163
#> 37: 0.01256667 0.01256667 30.000000000 0.97186667 0.000000000
#> 38: 0.24726009 0.29120537 30.000000000 0.61536667 0.024975182
#> 39: 0.14267367 0.16980694 30.000000000 0.81726667 0.008782943
#> 40: 0.56412736 0.63987995 0.083979077 -0.09190000 0.092656739
#> 41: 0.71998220 0.84636750 0.007532111 0.06133333 0.006931018
#> 42: 0.46368468 0.54490372 0.011313171 0.42486667 0.005539077
#> 43: 0.90251955 1.05310942 0.004804846 -0.15033333 0.005196465
#> 44: 1.03839112 1.14486626 0.002096183 -0.21590000 0.002402173
#> 45: 0.19832688 0.23289841 30.000000000 0.72833333 0.007472182
#> 46: 0.54083649 0.63547037 0.019685244 0.20183333 0.013344832
#> 47: 0.73806860 0.84884751 0.004278853 0.10913333 0.003823207
#> 48: 0.30574963 0.35592969 30.000000000 0.62720000 0.004699445
#> 49: 0.19909147 0.23175051 30.000000000 0.71623333 0.013054619
#> 50: 1.28856146 1.52231622 0.006501568 -0.76076667 0.009877882
#> 51: 1.64550960 1.81869399 0.001554925 -0.88523333 0.002461726
#> 52: 1.15120962 1.36693104 0.011295294 -0.63760000 0.014964922
#> 53: 1.36240014 1.58088594 0.003102882 -0.64316667 0.003627803
#> 54: 1.32845474 1.52484992 0.002821583 -0.59106667 0.003261246
#> 55: 1.22480959 1.44589294 0.011797654 -0.85010000 0.018211003
#> 56: 1.26028100 1.40891804 0.002124075 -0.44813333 0.002908819
#> 57: 1.31414196 1.53378544 0.004126866 -0.66630000 0.006208157
#> 58: 1.18823069 1.39705508 0.011541663 -0.74830000 0.019093562
#> 59: 0.82253648 0.96378586 0.025291861 -0.34083333 0.030462173
#> 60: 0.50079720 0.59001656 0.009069128 0.39763333 0.005532738
#> 61: 0.94067036 1.10926395 0.017069264 -0.40870000 0.021770780
#> 62: 1.15676086 1.35220803 0.003518715 -0.43993333 0.003926883
#> 63: 1.21810732 1.44505824 0.007845694 -0.68250000 0.011080523
#> 64: 1.01798232 1.19375008 0.020839662 -0.55216667 0.028935636
#> 65: 0.73506165 0.87121078 0.012275930 -0.04430000 0.012435379
#> 66: 1.30503768 1.53138485 0.006343314 -0.74286667 0.010860272
#> 67: 1.21295497 1.41975706 0.005422182 -0.63310000 0.008331080
#> 68: 0.90801590 1.04589054 0.039209092 -0.66776667 0.057979675
#> 69: 0.91033138 1.05593041 0.005013879 -0.13980000 0.005644554
#> 70: 0.66567051 0.78831518 0.017651636 0.01416667 0.017187956
#> 71: 1.50140284 1.69282924 0.002079722 -0.75150000 0.003379462
#> 72: 0.92221903 1.08549021 0.008896978 -0.26123333 0.011083282
#> 73: 1.13176002 1.31651313 0.004407585 -0.40610000 0.006019440
#> 74: 1.09398883 1.29535998 0.006947625 -0.41440000 0.009103145
#> 75: 1.12573401 1.32679092 0.016745695 -0.69520000 0.023147806
#> 76: 0.99680982 1.14178852 0.003824450 -0.20206667 0.004653230
#> 77: 1.28615912 1.51385999 0.009229506 -0.88796667 0.015867486
#> 78: 0.88779863 1.02895436 0.028449345 -0.53723333 0.043025854
#> 79: 1.00598048 1.16593241 0.034588147 -0.76266667 0.047602705
#> 80: 0.73295675 0.85892056 0.023671502 -0.19190000 0.026969054
#> 81: 0.39317207 0.46194732 0.053626857 0.41883333 0.019690231
#> 82: 0.36948898 0.42607970 0.087295888 0.31943333 0.056703027
#> 83: 0.51602601 0.57087256 0.143455577 -0.22873333 0.167033674
#> 84: 0.41879600 0.45743157 0.212648132 -0.02213333 0.212600715
#> 85: 0.26848103 0.30032538 0.344685074 0.42540000 0.131446499
#> 86: 0.36038724 0.40984406 0.117452572 0.26290000 0.086914958
#> 87: 0.22582416 0.25108633 30.000000000 0.48070000 0.150506549
#> 88: 0.40421325 0.45641866 0.126923290 0.18620000 0.104938005
#> 89: 0.25561534 0.27576952 0.482004214 0.34280000 0.262050505
#> 90: 0.55024130 0.61304737 0.120388567 -0.23676667 0.143651843
#> 91: 0.58191378 0.68366685 0.017638803 0.15233333 0.013459091
#> 92: 0.79635490 0.91959952 0.039776880 -0.45710000 0.052972634
#> 93: 1.13216866 1.33323831 0.006256750 -0.47600000 0.008730800
#> 94: 1.02494127 1.20800058 0.016682174 -0.54256667 0.022466542
#> 95: 0.75049546 0.85590610 0.058794620 -0.48653333 0.079484138
#> 96: 0.82301103 0.96481060 0.025824025 -0.31900000 0.030306953
#> 97: 1.26448110 1.49594653 0.008219032 -0.77343333 0.012547541
#> 98: 0.92251580 1.07425601 0.026077313 -0.49686667 0.037516853
#> 99: 0.80084964 0.89159948 0.096729600 -0.78626667 0.146270629
#> 100: 1.11481342 1.30596053 0.016239553 -0.76026667 0.026434030
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> <num> <num> <num> <num> <num> <num>
#> 1: 0.3651678148 1.0000000 1.9119007 0.9884406 1.660656e-07 0.0045303452
#> 2: 0.2663967900 1.0000000 2.2700932 0.9905292 8.267143e-08 0.0056700663
#> 3: 0.7669777183 1.0000000 3.1437068 0.9914280 5.831599e-08 0.0007996589
#> 4: 0.7468373651 1.0000000 3.3444924 0.9757902 2.207855e-06 0.0014589160
#> 5: 0.5776422640 1.0000000 3.7583023 0.9968734 1.709038e-09 0.0006971243
#> 6: 0.7767392076 1.0000000 0.2541701 0.7382169 9.179004e-03 0.0039751137
#> 7: 0.6856295469 1.0000000 2.2283677 0.9732050 3.149112e-06 0.0020708650
#> 8: 0.6122474630 1.0000000 2.2285708 0.9880579 1.861139e-07 0.0024924890
#> 9: 0.7754650425 1.0000000 2.2889985 0.9888129 1.480842e-07 0.0009916378
#> 10: -0.2226798163 1.0000000 2.2951127 0.9990488 2.654224e-11 0.0024404603
#> 11: 0.6470730550 1.0000000 2.8677996 0.9704197 4.451549e-06 0.0049211098
#> 12: 0.2295353843 1.0000000 3.2287691 0.9908815 7.239884e-08 0.0055504640
#> 13: 0.8985288362 1.0000000 5.0000000 0.8578698 1.082436e-03 0.0017311323
#> 14: 0.7779257424 1.0000000 5.0000000 0.9811907 9.126541e-07 0.0009519863
#> 15: 0.8271028214 1.0000000 2.2446169 0.9693003 5.069529e-06 0.0012425224
#> 16: 0.8069689420 1.0000000 2.1324423 0.9532749 2.205084e-05 0.0019540733
#> 17: 0.6734026973 1.0000000 2.0561031 0.9962473 3.237437e-09 0.0006692208
#> 18: 0.3158838755 1.0000000 2.8537073 0.9979296 4.037965e-10 0.0014073691
#> 19: 0.6786316274 1.0000000 2.6189994 0.9900052 9.981764e-08 0.0015756760
#> 20: 0.7126300563 1.0000000 2.7803450 0.9884951 1.633382e-07 0.0014199653
#> 21: 0.6972688823 1.0000000 2.2630422 0.9939342 1.738238e-08 0.0009119932
#> 22: 0.2671164396 1.0000000 3.2188686 0.9942855 1.410692e-08 0.0033809061
#> 23: 0.5707831317 1.0000000 2.2058511 0.9885236 1.619263e-07 0.0035039079
#> 24: 0.5679295931 1.0000000 2.2341289 0.9974080 8.865540e-10 0.0007253857
#> 25: 0.5830557926 1.0000000 3.0941181 0.9915566 5.531131e-08 0.0020546400
#> 26: 0.5234219383 1.0000000 2.5223390 0.9945689 1.180644e-08 0.0018728900
#> 27: 0.9843851852 0.9843852 0.0001000 0.0000000 5.051366e-01 0.0026667731
#> 28: 0.2627284849 1.0000000 1.7543375 0.9929829 2.894338e-08 0.0058346518
#> 29: 0.8134059397 1.0000000 2.0261477 0.9701477 4.596431e-06 0.0017203009
#> 30: 0.5300584965 1.0000000 2.2706141 0.9915850 5.466156e-08 0.0025042007
#> 31: 0.8175800194 1.0000000 2.9545779 0.9263136 1.086067e-04 0.0047546911
#> 32: 0.8497191486 1.0000000 5.0000000 0.9414806 4.847844e-05 0.0028277725
#> 33: 0.7745509842 1.0000000 5.0000000 0.9905919 8.077212e-08 0.0009703665
#> 34: 0.9091685072 1.0000000 5.0000000 0.8703307 7.851092e-04 0.0036147863
#> 35: 0.5909223718 1.0000000 3.3653065 0.9965291 2.463576e-09 0.0007708945
#> 36: 0.8144193534 1.0000000 3.2484642 0.9602404 1.253272e-05 0.0023079249
#> 37: 0.9874333333 0.9874333 0.0001000 0.0000000 5.226792e-01 0.0045005377
#> 38: 0.6190909106 1.0000000 5.0000000 0.9916347 5.354032e-08 0.0021490509
#> 39: 0.8126203033 1.0000000 2.8923837 0.9340415 7.369655e-05 0.0030096935
#> 40: -0.1100555561 1.0000000 2.0231247 0.9954539 6.335023e-09 0.0101608866
#> 41: 0.0843948493 1.0000000 2.2228625 0.9989540 3.700785e-11 0.0011299281
#> 42: 0.4280422001 1.0000000 2.7144943 0.9939185 1.754023e-08 0.0025486690
#> 43: -0.1044494537 1.0000000 2.4212065 0.9902549 9.135969e-08 0.0134618257
#> 44: -0.1620560072 1.0000000 2.0604060 0.9892455 1.289925e-07 0.0102617483
#> 45: 0.7451155399 1.0000000 2.0612207 0.9805388 1.028230e-06 0.0016676158
#> 46: 0.2444903289 1.0000000 1.7269837 0.9955545 5.857477e-09 0.0035994749
#> 47: 0.1316629628 1.0000000 2.7142277 0.9946978 1.085451e-08 0.0041780160
#> 48: 0.6307693263 1.0000000 2.6162346 0.9927082 3.310784e-08 0.0012196886
#> 49: 0.7222776333 1.0000000 1.3911231 0.9644174 8.498288e-06 0.0035483729
#> 50: -0.7215144153 1.0000000 2.1356334 0.9986787 8.385582e-11 0.0054197260
#> 51: -0.8445230124 1.0000000 2.1530486 0.9970059 1.468626e-09 0.0074471434
#> 52: -0.6348290617 1.0000000 2.9134838 0.9975549 7.227836e-10 0.0105548724
#> 53: -0.5906663271 1.0000000 4.9901264 0.9835173 5.749117e-07 0.0479741017
#> 54: -0.5306044465 1.0000000 4.9947313 0.9909207 7.131558e-08 0.0204750192
#> 55: -0.7932565672 1.0000000 2.1890242 0.9987491 6.923104e-11 0.0064150301
#> 56: -0.4405596014 1.0000000 2.0096850 0.9868501 2.607523e-07 0.0214141959
#> 57: -0.6475910270 1.0000000 2.0345801 0.9915706 5.499090e-08 0.0270484156
#> 58: -0.7531963509 1.0000000 1.8253213 0.9987855 6.243166e-11 0.0057202466
#> 59: -0.3102371436 1.0000000 2.5952204 0.9989539 3.702390e-11 0.0032347548
#> 60: 0.3824493623 1.0000000 2.9294992 0.9857446 3.458839e-07 0.0066776424
#> 61: -0.4169392990 1.0000000 2.4926426 0.9974568 8.294838e-10 0.0090820977
#> 62: -0.3641218697 1.0000000 4.9850173 0.9908614 7.295866e-08 0.0208479700
#> 63: -0.6541862131 1.0000000 2.4231874 0.9914850 5.697009e-08 0.0358041319
#> 64: -0.6074320061 1.0000000 2.4227680 0.9960819 3.765019e-09 0.0174257673
#> 65: -0.0153061841 1.0000000 2.3365273 0.9964806 2.586138e-09 0.0056269403
#> 66: -0.7689648974 1.0000000 1.7320650 0.9970436 1.404914e-09 0.0123458770
#> 67: -0.5835770177 1.0000000 1.8007551 0.9976480 6.309898e-10 0.0073846724
#> 68: -0.6255619766 1.0000000 2.0742923 0.9975373 7.412210e-10 0.0119795999
#> 69: -0.1277776181 1.0000000 1.9207939 0.9938926 1.780359e-08 0.0087658850
#> 70: 0.0342563614 1.0000000 2.6661846 0.9973400 9.707612e-10 0.0042664707
#> 71: -0.7476426517 1.0000000 1.8834936 0.9984594 1.435180e-10 0.0039640590
#> 72: -0.2532259879 1.0000000 1.8648542 0.9995596 1.792360e-12 0.0009511982
#> 73: -0.4137519625 1.0000000 1.9345991 0.9993732 6.163698e-12 0.0014555916
#> 74: -0.4443998175 1.0000000 2.3534208 0.9951423 7.989316e-09 0.0137384037
#> 75: -0.7126817181 1.0000000 2.7365478 0.9986032 1.018578e-10 0.0071007044
#> 76: -0.2065860191 1.0000000 1.7631520 0.9967875 1.879027e-09 0.0045316079
#> 77: -0.8438328827 1.0000000 1.8245692 0.9973253 9.896588e-10 0.0137058624
#> 78: -0.5033105133 1.0000000 1.6835691 0.9980112 3.507995e-10 0.0074336916
#> 79: -0.7350666349 1.0000000 2.8313491 0.9990251 2.892854e-11 0.0055864178
#> 80: -0.1438326892 1.0000000 1.9386164 0.9958942 4.434905e-09 0.0087060442
#> 81: 0.4170287342 1.0000000 1.7926586 0.9981406 2.772138e-10 0.0009814830
#> 82: 0.3413600699 1.0000000 2.6605690 0.9970120 1.458224e-09 0.0025565632
#> 83: -0.1599302533 1.0000000 1.8237894 0.9955606 5.829534e-09 0.0104168368
#> 84: 0.0002979208 1.0000000 2.6726325 0.9985093 1.279117e-10 0.0027912514
#> 85: 0.4295060402 1.0000000 2.0321759 0.9950986 8.243686e-09 0.0029000027
#> 86: 0.3003216477 1.0000000 3.0484446 0.9946346 1.131362e-08 0.0051502481
#> 87: 0.5048265847 1.0000000 3.5683198 0.9917107 5.185758e-08 0.0042469987
#> 88: 0.1831084883 1.0000000 2.3975662 0.9924392 3.758273e-08 0.0100206531
#> 89: 0.3552684841 1.0000000 2.0342894 0.9950033 8.818716e-09 0.0038048777
#> 90: -0.1933830016 1.0000000 1.8507842 0.9967431 1.971582e-09 0.0085515416
#> 91: 0.1860626932 1.0000000 1.7209131 0.9966220 2.240260e-09 0.0032422970
#> 92: -0.4013139858 1.0000000 2.0567782 0.9965388 2.439530e-09 0.0120338036
#> 93: -0.4866785556 1.0000000 2.0400478 0.9952028 7.646630e-09 0.0143425595
#> 94: -0.5517780648 1.0000000 2.4980285 0.9985723 1.099614e-10 0.0059898596
#> 95: -0.4303883285 1.0000000 2.0596328 0.9969133 1.633858e-09 0.0120169616
#> 96: -0.3098387168 1.0000000 3.0125648 0.9977677 5.256069e-10 0.0074113065
#> 97: -0.7490788673 1.0000000 2.1640592 0.9987682 6.560411e-11 0.0055870262
#> 98: -0.5239352601 1.0000000 1.9707233 0.9955609 5.828304e-09 0.0174009206
#> 99: -0.7443040083 1.0000000 2.2046853 0.9985705 1.104466e-10 0.0081610637
#> 100: -0.7340189608 1.0000000 1.8543083 0.9987249 7.403286e-11 0.0064842414
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> GR Sd Avg Fit Type GR maxlog10Concentration N Conc Fit Source
#> <num> <char> <num> <int> <char>
#> 1: 0.03203268 DRC3pHillFitModelFixS0 1 9 gDR
#> 2: 0.03075240 DRC3pHillFitModelFixS0 1 9 gDR
#> 3: 0.02000573 DRC3pHillFitModelFixS0 1 9 gDR
#> 4: 0.02214360 DRC3pHillFitModelFixS0 1 9 gDR
#> 5: 0.03066180 DRC3pHillFitModelFixS0 1 9 gDR
#> 6: 0.02346065 DRC3pHillFitModelFixS0 1 9 gDR
#> 7: 0.02679197 DRC3pHillFitModelFixS0 1 9 gDR
#> 8: 0.01983125 DRC3pHillFitModelFixS0 1 9 gDR
#> 9: 0.01910174 DRC3pHillFitModelFixS0 1 9 gDR
#> 10: 0.07130873 DRC3pHillFitModelFixS0 1 9 gDR
#> 11: 0.02101516 DRC3pHillFitModelFixS0 1 9 gDR
#> 12: 0.03850179 DRC3pHillFitModelFixS0 1 9 gDR
#> 13: 0.03205436 DRC3pHillFitModelFixS0 1 9 gDR
#> 14: 0.02326291 DRC3pHillFitModelFixS0 1 9 gDR
#> 15: 0.02352653 DRC3pHillFitModelFixS0 1 9 gDR
#> 16: 0.02344649 DRC3pHillFitModelFixS0 1 9 gDR
#> 17: 0.03340578 DRC3pHillFitModelFixS0 1 9 gDR
#> 18: 0.03448935 DRC3pHillFitModelFixS0 1 9 gDR
#> 19: 0.02377445 DRC3pHillFitModelFixS0 1 9 gDR
#> 20: 0.02630609 DRC3pHillFitModelFixS0 1 9 gDR
#> 21: 0.02570997 DRC3pHillFitModelFixS0 1 9 gDR
#> 22: 0.03926750 DRC3pHillFitModelFixS0 1 9 gDR
#> 23: 0.02824974 DRC3pHillFitModelFixS0 1 9 gDR
#> 24: 0.02856021 DRC3pHillFitModelFixS0 1 9 gDR
#> 25: 0.02557931 DRC3pHillFitModelFixS0 1 9 gDR
#> 26: 0.02875531 DRC3pHillFitModelFixS0 1 9 gDR
#> 27: 0.02503984 DRCConstantFitResult 1 9 gDR
#> 28: 0.03690901 DRC3pHillFitModelFixS0 1 9 gDR
#> 29: 0.02418509 DRC3pHillFitModelFixS0 1 9 gDR
#> 30: 0.02944348 DRC3pHillFitModelFixS0 1 9 gDR
#> 31: 0.02872952 DRC3pHillFitModelFixS0 1 9 gDR
#> 32: 0.03452733 DRC3pHillFitModelFixS0 1 9 gDR
#> 33: 0.03283285 DRC3pHillFitModelFixS0 1 9 gDR
#> 34: 0.02600261 DRC3pHillFitModelFixS0 1 9 gDR
#> 35: 0.02690396 DRC3pHillFitModelFixS0 1 9 gDR
#> 36: 0.03016809 DRC3pHillFitModelFixS0 1 9 gDR
#> 37: 0.02836629 DRCConstantFitResult 1 9 gDR
#> 38: 0.02649059 DRC3pHillFitModelFixS0 1 9 gDR
#> 39: 0.02525543 DRC3pHillFitModelFixS0 1 9 gDR
#> 40: 0.05432540 DRC3pHillFitModelFixS0 1 9 gDR
#> 41: 0.04268871 DRC3pHillFitModelFixS0 1 9 gDR
#> 42: 0.03167032 DRC3pHillFitModelFixS0 1 9 gDR
#> 43: 0.04581144 DRC3pHillFitModelFixS0 1 9 gDR
#> 44: 0.04712220 DRC3pHillFitModelFixS0 1 9 gDR
#> 45: 0.03663539 DRC3pHillFitModelFixS0 1 9 gDR
#> 46: 0.04114510 DRC3pHillFitModelFixS0 1 9 gDR
#> 47: 0.02957059 DRC3pHillFitModelFixS0 1 9 gDR
#> 48: 0.04836989 DRC3pHillFitModelFixS0 1 9 gDR
#> 49: 0.01995472 DRC3pHillFitModelFixS0 1 9 gDR
#> 50: 0.09569389 DRC3pHillFitModelFixS0 1 9 gDR
#> 51: 0.05883646 DRC3pHillFitModelFixS0 1 9 gDR
#> 52: 0.05621152 DRC3pHillFitModelFixS0 1 9 gDR
#> 53: 0.06787391 DRC3pHillFitModelFixS0 1 9 gDR
#> 54: 0.06158907 DRC3pHillFitModelFixS0 1 9 gDR
#> 55: 0.07877147 DRC3pHillFitModelFixS0 1 9 gDR
#> 56: 0.06417974 DRC3pHillFitModelFixS0 1 9 gDR
#> 57: 0.06360624 DRC3pHillFitModelFixS0 1 9 gDR
#> 58: 0.08699730 DRC3pHillFitModelFixS0 1 9 gDR
#> 59: 0.03924611 DRC3pHillFitModelFixS0 1 9 gDR
#> 60: 0.02995868 DRC3pHillFitModelFixS0 1 9 gDR
#> 61: 0.04815310 DRC3pHillFitModelFixS0 1 9 gDR
#> 62: 0.05756475 DRC3pHillFitModelFixS0 1 9 gDR
#> 63: 0.05772902 DRC3pHillFitModelFixS0 1 9 gDR
#> 64: 0.05544735 DRC3pHillFitModelFixS0 1 9 gDR
#> 65: 0.04812444 DRC3pHillFitModelFixS0 1 9 gDR
#> 66: 0.10139524 DRC3pHillFitModelFixS0 1 9 gDR
#> 67: 0.06146191 DRC3pHillFitModelFixS0 1 9 gDR
#> 68: 0.05594040 DRC3pHillFitModelFixS0 1 9 gDR
#> 69: 0.04122973 DRC3pHillFitModelFixS0 1 9 gDR
#> 70: 0.03674990 DRC3pHillFitModelFixS0 1 9 gDR
#> 71: 0.07586112 DRC3pHillFitModelFixS0 1 9 gDR
#> 72: 0.04007412 DRC3pHillFitModelFixS0 1 9 gDR
#> 73: 0.06975153 DRC3pHillFitModelFixS0 1 9 gDR
#> 74: 0.03442655 DRC3pHillFitModelFixS0 1 9 gDR
#> 75: 0.06771926 DRC3pHillFitModelFixS0 1 9 gDR
#> 76: 0.04856655 DRC3pHillFitModelFixS0 1 9 gDR
#> 77: 0.06455336 DRC3pHillFitModelFixS0 1 9 gDR
#> 78: 0.06514096 DRC3pHillFitModelFixS0 1 9 gDR
#> 79: 0.04920195 DRC3pHillFitModelFixS0 1 9 gDR
#> 80: 0.05402095 DRC3pHillFitModelFixS0 1 9 gDR
#> 81: 0.04906576 DRC3pHillFitModelFixS0 1 9 gDR
#> 82: 0.04751873 DRC3pHillFitModelFixS0 1 9 gDR
#> 83: 0.04074026 DRC3pHillFitModelFixS0 1 9 gDR
#> 84: 0.05740278 DRC3pHillFitModelFixS0 1 9 gDR
#> 85: 0.04942568 DRC3pHillFitModelFixS0 1 9 gDR
#> 86: 0.04407493 DRC3pHillFitModelFixS0 1 9 gDR
#> 87: 0.05235831 DRC3pHillFitModelFixS0 1 9 gDR
#> 88: 0.04841497 DRC3pHillFitModelFixS0 1 9 gDR
#> 89: 0.05300916 DRC3pHillFitModelFixS0 1 9 gDR
#> 90: 0.03421832 DRC3pHillFitModelFixS0 1 9 gDR
#> 91: 0.04289095 DRC3pHillFitModelFixS0 1 9 gDR
#> 92: 0.05008110 DRC3pHillFitModelFixS0 1 9 gDR
#> 93: 0.04267612 DRC3pHillFitModelFixS0 1 9 gDR
#> 94: 0.06048658 DRC3pHillFitModelFixS0 1 9 gDR
#> 95: 0.05057676 DRC3pHillFitModelFixS0 1 9 gDR
#> 96: 0.03418831 DRC3pHillFitModelFixS0 1 9 gDR
#> 97: 0.04674118 DRC3pHillFitModelFixS0 1 9 gDR
#> 98: 0.04602459 DRC3pHillFitModelFixS0 1 9 gDR
#> 99: 0.06333498 DRC3pHillFitModelFixS0 1 9 gDR
#> 100: 0.07007818 DRC3pHillFitModelFixS0 1 9 gDR
#> GR Sd Avg Fit Type GR maxlog10Concentration N Conc Fit Source
#> Gnumber Drug Name Drug MOA Duration Clid Cell Line Name Tissue
#> <char> <char> <char> <num> <char> <char> <char>
#> 1: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 2: G00003 drug_003 moa_A 72 CL00011 cellline_BA tissue_x
#> 3: G00004 drug_004 moa_A 72 CL00011 cellline_BA tissue_x
#> 4: G00005 drug_005 moa_A 72 CL00011 cellline_BA tissue_x
#> 5: G00006 drug_006 moa_A 72 CL00011 cellline_BA tissue_x
#> 6: G00007 drug_007 moa_A 72 CL00011 cellline_BA tissue_x
#> 7: G00008 drug_008 moa_A 72 CL00011 cellline_BA tissue_x
#> 8: G00009 drug_009 moa_A 72 CL00011 cellline_BA tissue_x
#> 9: G00010 drug_010 moa_A 72 CL00011 cellline_BA tissue_x
#> 10: G00011 drug_011 moa_B 72 CL00011 cellline_BA tissue_x
#> 11: G00002 drug_002 moa_A 72 CL00012 cellline_CA tissue_x
#> 12: G00003 drug_003 moa_A 72 CL00012 cellline_CA tissue_x
#> 13: G00004 drug_004 moa_A 72 CL00012 cellline_CA tissue_x
#> 14: G00005 drug_005 moa_A 72 CL00012 cellline_CA tissue_x
#> 15: G00006 drug_006 moa_A 72 CL00012 cellline_CA tissue_x
#> 16: G00007 drug_007 moa_A 72 CL00012 cellline_CA tissue_x
#> 17: G00008 drug_008 moa_A 72 CL00012 cellline_CA tissue_x
#> 18: G00009 drug_009 moa_A 72 CL00012 cellline_CA tissue_x
#> 19: G00010 drug_010 moa_A 72 CL00012 cellline_CA tissue_x
#> 20: G00011 drug_011 moa_B 72 CL00012 cellline_CA tissue_x
#> 21: G00002 drug_002 moa_A 72 CL00013 cellline_DA tissue_x
#> 22: G00003 drug_003 moa_A 72 CL00013 cellline_DA tissue_x
#> 23: G00004 drug_004 moa_A 72 CL00013 cellline_DA tissue_x
#> 24: G00005 drug_005 moa_A 72 CL00013 cellline_DA tissue_x
#> 25: G00006 drug_006 moa_A 72 CL00013 cellline_DA tissue_x
#> 26: G00007 drug_007 moa_A 72 CL00013 cellline_DA tissue_x
#> 27: G00008 drug_008 moa_A 72 CL00013 cellline_DA tissue_x
#> 28: G00009 drug_009 moa_A 72 CL00013 cellline_DA tissue_x
#> 29: G00010 drug_010 moa_A 72 CL00013 cellline_DA tissue_x
#> 30: G00011 drug_011 moa_B 72 CL00013 cellline_DA tissue_x
#> 31: G00002 drug_002 moa_A 72 CL00014 cellline_EA tissue_x
#> 32: G00003 drug_003 moa_A 72 CL00014 cellline_EA tissue_x
#> 33: G00004 drug_004 moa_A 72 CL00014 cellline_EA tissue_x
#> 34: G00005 drug_005 moa_A 72 CL00014 cellline_EA tissue_x
#> 35: G00006 drug_006 moa_A 72 CL00014 cellline_EA tissue_x
#> 36: G00007 drug_007 moa_A 72 CL00014 cellline_EA tissue_x
#> 37: G00008 drug_008 moa_A 72 CL00014 cellline_EA tissue_x
#> 38: G00009 drug_009 moa_A 72 CL00014 cellline_EA tissue_x
#> 39: G00010 drug_010 moa_A 72 CL00014 cellline_EA tissue_x
#> 40: G00011 drug_011 moa_B 72 CL00014 cellline_EA tissue_x
#> 41: G00002 drug_002 moa_A 72 CL00015 cellline_FA tissue_x
#> 42: G00003 drug_003 moa_A 72 CL00015 cellline_FA tissue_x
#> 43: G00004 drug_004 moa_A 72 CL00015 cellline_FA tissue_x
#> 44: G00005 drug_005 moa_A 72 CL00015 cellline_FA tissue_x
#> 45: G00006 drug_006 moa_A 72 CL00015 cellline_FA tissue_x
#> 46: G00007 drug_007 moa_A 72 CL00015 cellline_FA tissue_x
#> 47: G00008 drug_008 moa_A 72 CL00015 cellline_FA tissue_x
#> 48: G00009 drug_009 moa_A 72 CL00015 cellline_FA tissue_x
#> 49: G00010 drug_010 moa_A 72 CL00015 cellline_FA tissue_x
#> 50: G00011 drug_011 moa_B 72 CL00015 cellline_FA tissue_x
#> 51: G00002 drug_002 moa_A 72 CL00016 cellline_GB tissue_y
#> 52: G00003 drug_003 moa_A 72 CL00016 cellline_GB tissue_y
#> 53: G00004 drug_004 moa_A 72 CL00016 cellline_GB tissue_y
#> 54: G00005 drug_005 moa_A 72 CL00016 cellline_GB tissue_y
#> 55: G00006 drug_006 moa_A 72 CL00016 cellline_GB tissue_y
#> 56: G00007 drug_007 moa_A 72 CL00016 cellline_GB tissue_y
#> 57: G00008 drug_008 moa_A 72 CL00016 cellline_GB tissue_y
#> 58: G00009 drug_009 moa_A 72 CL00016 cellline_GB tissue_y
#> 59: G00010 drug_010 moa_A 72 CL00016 cellline_GB tissue_y
#> 60: G00011 drug_011 moa_B 72 CL00016 cellline_GB tissue_y
#> 61: G00002 drug_002 moa_A 72 CL00017 cellline_HB tissue_y
#> 62: G00003 drug_003 moa_A 72 CL00017 cellline_HB tissue_y
#> 63: G00004 drug_004 moa_A 72 CL00017 cellline_HB tissue_y
#> 64: G00005 drug_005 moa_A 72 CL00017 cellline_HB tissue_y
#> 65: G00006 drug_006 moa_A 72 CL00017 cellline_HB tissue_y
#> 66: G00007 drug_007 moa_A 72 CL00017 cellline_HB tissue_y
#> 67: G00008 drug_008 moa_A 72 CL00017 cellline_HB tissue_y
#> 68: G00009 drug_009 moa_A 72 CL00017 cellline_HB tissue_y
#> 69: G00010 drug_010 moa_A 72 CL00017 cellline_HB tissue_y
#> 70: G00011 drug_011 moa_B 72 CL00017 cellline_HB tissue_y
#> 71: G00002 drug_002 moa_A 72 CL00018 cellline_IB tissue_y
#> 72: G00003 drug_003 moa_A 72 CL00018 cellline_IB tissue_y
#> 73: G00004 drug_004 moa_A 72 CL00018 cellline_IB tissue_y
#> 74: G00005 drug_005 moa_A 72 CL00018 cellline_IB tissue_y
#> 75: G00006 drug_006 moa_A 72 CL00018 cellline_IB tissue_y
#> 76: G00007 drug_007 moa_A 72 CL00018 cellline_IB tissue_y
#> 77: G00008 drug_008 moa_A 72 CL00018 cellline_IB tissue_y
#> 78: G00009 drug_009 moa_A 72 CL00018 cellline_IB tissue_y
#> 79: G00010 drug_010 moa_A 72 CL00018 cellline_IB tissue_y
#> 80: G00011 drug_011 moa_B 72 CL00018 cellline_IB tissue_y
#> 81: G00002 drug_002 moa_A 72 CL00019 cellline_JB tissue_z
#> 82: G00003 drug_003 moa_A 72 CL00019 cellline_JB tissue_z
#> 83: G00004 drug_004 moa_A 72 CL00019 cellline_JB tissue_z
#> 84: G00005 drug_005 moa_A 72 CL00019 cellline_JB tissue_z
#> 85: G00006 drug_006 moa_A 72 CL00019 cellline_JB tissue_z
#> 86: G00007 drug_007 moa_A 72 CL00019 cellline_JB tissue_z
#> 87: G00008 drug_008 moa_A 72 CL00019 cellline_JB tissue_z
#> 88: G00009 drug_009 moa_A 72 CL00019 cellline_JB tissue_z
#> 89: G00010 drug_010 moa_A 72 CL00019 cellline_JB tissue_z
#> 90: G00011 drug_011 moa_B 72 CL00019 cellline_JB tissue_z
#> 91: G00002 drug_002 moa_A 72 CL00020 cellline_KB tissue_z
#> 92: G00003 drug_003 moa_A 72 CL00020 cellline_KB tissue_z
#> 93: G00004 drug_004 moa_A 72 CL00020 cellline_KB tissue_z
#> 94: G00005 drug_005 moa_A 72 CL00020 cellline_KB tissue_z
#> 95: G00006 drug_006 moa_A 72 CL00020 cellline_KB tissue_z
#> 96: G00007 drug_007 moa_A 72 CL00020 cellline_KB tissue_z
#> 97: G00008 drug_008 moa_A 72 CL00020 cellline_KB tissue_z
#> 98: G00009 drug_009 moa_A 72 CL00020 cellline_KB tissue_z
#> 99: G00010 drug_010 moa_A 72 CL00020 cellline_KB tissue_z
#> 100: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> Gnumber Drug Name Drug MOA Duration Clid Cell Line Name Tissue
#> Reference Division Time RV Mean RV AOC RV AOC within set range
#> <num> <num> <num> <num>
#> 1: 26 0.4466890 0.55331098 0.62771204
#> 2: 26 0.3939872 0.60601279 0.69549935
#> 3: 26 0.7989283 0.20107172 0.23854321
#> 4: 26 0.7292519 0.27074809 0.30829556
#> 5: 26 0.5948205 0.40517951 0.47306641
#> 6: 26 0.9153135 0.08468651 0.09862965
#> 7: 26 0.6627378 0.33726218 0.37222482
#> 8: 26 0.6541186 0.34588137 0.40814181
#> 9: 26 0.8247285 0.17527151 0.20515620
#> 10: 26 0.3682302 0.63176984 0.74702096
#> 11: 30 0.6926178 0.30738217 0.35949454
#> 12: 30 0.3979780 0.60202205 0.68371983
#> 13: 30 0.9100259 0.08997415 0.10791352
#> 14: 30 0.7873037 0.21269633 0.24486763
#> 15: 30 0.8494189 0.15058108 0.17760851
#> 16: 30 0.8169558 0.18304416 0.20901519
#> 17: 30 0.7755540 0.22444601 0.26336442
#> 18: 30 0.5212853 0.47871472 0.56881144
#> 19: 30 0.7463491 0.25365094 0.30161904
#> 20: 30 0.7616189 0.23838111 0.28326524
#> 21: 34 0.7992747 0.20072525 0.23709408
#> 22: 34 0.4668574 0.53314262 0.61173591
#> 23: 34 0.7261649 0.27383514 0.32331797
#> 24: 34 0.7151504 0.28484957 0.33700199
#> 25: 34 0.6956589 0.30434108 0.36205275
#> 26: 34 0.6779461 0.32205391 0.38244556
#> 27: 34 0.9838111 0.01618889 0.01618889
#> 28: 34 0.5806643 0.41933574 0.49233133
#> 29: 34 0.8776200 0.12238003 0.14379727
#> 30: 34 0.6609849 0.33901514 0.39942016
#> 31: 38 0.8710149 0.12898507 0.15337431
#> 32: 38 0.9173053 0.08269470 0.09639032
#> 33: 38 0.8778150 0.12218503 0.14245939
#> 34: 38 0.9437698 0.05623016 0.06647635
#> 35: 38 0.7144618 0.28553821 0.33774750
#> 36: 38 0.8874428 0.11255721 0.13302031
#> 37: 38 0.9883815 0.01161852 0.01161852
#> 38: 38 0.7852841 0.21471593 0.25298214
#> 39: 38 0.8700763 0.12992370 0.15434173
#> 40: 38 0.5865688 0.41343121 0.47176921
#> 41: 42 0.4828015 0.51719847 0.60667873
#> 42: 42 0.6425053 0.35749468 0.41943708
#> 43: 42 0.3805017 0.61949830 0.71885082
#> 44: 42 0.2977827 0.70221726 0.76597220
#> 45: 42 0.8375294 0.16247062 0.19070324
#> 46: 42 0.5962853 0.40371474 0.47449665
#> 47: 42 0.4657079 0.53429209 0.61134861
#> 48: 42 0.7549529 0.24504707 0.28487547
#> 49: 42 0.8372120 0.16278796 0.18968302
#> 50: 42 0.2524798 0.74752018 0.88177300
#> 51: 46 0.1021560 0.89784398 0.97368081
#> 52: 46 0.3319590 0.66804098 0.79488065
#> 53: 46 0.2102313 0.78976874 0.90450614
#> 54: 46 0.2100452 0.78995479 0.88824111
#> 55: 46 0.3146779 0.68532206 0.81208812
#> 56: 46 0.2311182 0.76888180 0.84899908
#> 57: 46 0.2364875 0.76351250 0.88498708
#> 58: 46 0.3235937 0.67640628 0.79810483
#> 59: 46 0.4821997 0.51780026 0.60821155
#> 60: 46 0.6425491 0.35745090 0.42057145
#> 61: 50 0.4403251 0.55967489 0.66129430
#> 62: 50 0.3158261 0.68417394 0.79476913
#> 63: 50 0.3117162 0.68828381 0.81859408
#> 64: 50 0.4144975 0.58550254 0.68838500
#> 65: 50 0.5330401 0.46695992 0.55422115
#> 66: 50 0.2753604 0.72463961 0.84954049
#> 67: 50 0.2988946 0.70110537 0.81877562
#> 68: 50 0.4775211 0.52247889 0.60461228
#> 69: 50 0.4307934 0.56920661 0.65813446
#> 70: 50 0.5740133 0.42598675 0.50486302
#> 71: 54 0.1817987 0.81820132 0.91385902
#> 72: 54 0.4557736 0.54422640 0.64062126
#> 73: 54 0.3473656 0.65263436 0.75662897
#> 74: 54 0.3722520 0.62774797 0.74215883
#> 75: 54 0.3820939 0.61790607 0.72975315
#> 76: 54 0.4088002 0.59119981 0.67444555
#> 77: 54 0.3086007 0.69139927 0.81546273
#> 78: 54 0.4906996 0.50930040 0.59207687
#> 79: 54 0.4496388 0.55036124 0.63963532
#> 80: 54 0.5613320 0.43866803 0.51481053
#> 81: 58 0.7645125 0.23548748 0.27674936
#> 82: 58 0.7799746 0.22002537 0.25385986
#> 83: 58 0.7029485 0.29705152 0.32948401
#> 84: 58 0.7566058 0.24339421 0.26629466
#> 85: 58 0.8388170 0.16118297 0.18043264
#> 86: 58 0.7862239 0.21377605 0.24324624
#> 87: 58 0.8640795 0.13592048 0.15119347
#> 88: 58 0.7614460 0.23855403 0.26963522
#> 89: 58 0.8471580 0.15284198 0.16513000
#> 90: 58 0.6842658 0.31573420 0.35272441
#> 91: 62 0.6737095 0.32629051 0.38341599
#> 92: 62 0.5683750 0.43162499 0.49907540
#> 93: 62 0.3916886 0.60831136 0.71651338
#> 94: 62 0.4519141 0.54808592 0.64651950
#> 95: 62 0.5938560 0.40614404 0.46394440
#> 96: 62 0.5525910 0.44740898 0.52483930
#> 97: 62 0.3356482 0.66435184 0.78615325
#> 98: 62 0.5045079 0.49549211 0.57777110
#> 99: 62 0.5769999 0.42300010 0.47231044
#> 100: 62 0.4117805 0.58821946 0.69005808
#> Reference Division Time RV Mean RV AOC RV AOC within set range
#> IC50 E Max EC50 E Inf E0 h RV
#> <num> <num> <num> <num> <num> <num>
#> 1: 0.007253171 0.32793333 0.003795893 0.34682665 1.0000000 1.827031
#> 2: 0.005655581 0.27413333 0.003962986 0.28319787 1.0000000 2.349599
#> 3: 30.000000000 0.70636667 0.016546380 0.71001484 1.0000000 3.159939
#> 4: 30.000000000 0.67963333 0.003304929 0.68717703 1.0000000 2.869796
#> 5: 30.000000000 0.50873333 0.004129702 0.51907021 1.0000000 3.829228
#> 6: 30.000000000 0.86246667 0.023423073 0.87074092 1.0000000 1.396984
#> 7: 30.000000000 0.59466667 0.002397623 0.62344087 1.0000000 2.285910
#> 8: 30.000000000 0.56796667 0.008060179 0.55098117 1.0000000 2.239456
#> 9: 30.000000000 0.72036667 0.031276165 0.71953596 1.0000000 2.336379
#> 10: 0.019384886 0.07090000 0.018136158 0.07568110 1.0000000 2.464822
#> 11: 30.000000000 0.63853333 0.004774753 0.62816339 1.0000000 2.919115
#> 12: 0.003821711 0.27726667 0.003008201 0.31309370 1.0000000 4.111036
#> 13: 30.000000000 0.87040000 0.008254080 0.88286917 1.0000000 5.000000
#> 14: 30.000000000 0.77096667 0.003354506 0.75408088 1.0000000 5.000000
#> 15: 30.000000000 0.80546667 0.007866347 0.80517426 1.0000000 2.241526
#> 16: 30.000000000 0.76806667 0.003815689 0.78433529 1.0000000 2.178830
#> 17: 30.000000000 0.64960000 0.025909149 0.65208728 1.0000000 2.036162
#> 18: 0.015334114 0.35873333 0.009338353 0.36576263 1.0000000 2.651473
#> 19: 30.000000000 0.65570000 0.010664967 0.65748115 1.0000000 2.703715
#> 20: 30.000000000 0.68473333 0.008285395 0.68946503 1.0000000 2.768447
#> 21: 30.000000000 0.69726667 0.018014759 0.70662235 1.0000000 2.255304
#> 22: 0.005175017 0.36916667 0.003431788 0.38161495 1.0000000 3.507307
#> 23: 30.000000000 0.60056667 0.017991972 0.59983667 1.0000000 2.193421
#> 24: 30.000000000 0.59763333 0.014539308 0.59720052 1.0000000 2.214172
#> 25: 30.000000000 0.59926667 0.007397397 0.60975201 1.0000000 3.069376
#> 26: 30.000000000 0.55096667 0.011148175 0.56228258 1.0000000 2.535963
#> 27: 30.000000000 0.97033333 NA 0.98381111 0.9838111 0.000100
#> 28: 0.044349772 0.35713333 0.019771994 0.37777983 1.0000000 1.743888
#> 29: 30.000000000 0.82200000 0.023835769 0.81289660 1.0000000 2.039182
#> 30: 30.000000000 0.55890000 0.007078033 0.56771316 1.0000000 2.322658
#> 31: 30.000000000 0.82480000 0.007404640 0.83458186 1.0000000 3.013686
#> 32: 30.000000000 0.84193333 0.038642612 0.86268158 1.0000000 5.000000
#> 33: 30.000000000 0.78713333 0.038237333 0.79748718 1.0000000 5.000000
#> 34: 30.000000000 0.91773333 0.020858876 0.91588511 1.0000000 5.000000
#> 35: 30.000000000 0.64843333 0.005482997 0.64836791 1.0000000 3.372144
#> 36: 30.000000000 0.80563333 0.020762148 0.83175068 1.0000000 3.262119
#> 37: 30.000000000 0.97366667 NA 0.98838148 0.9883815 0.000100
#> 38: 30.000000000 0.66726667 0.024503188 0.67026768 1.0000000 5.000000
#> 39: 30.000000000 0.83416667 0.008516796 0.83009341 1.0000000 2.706836
#> 40: 0.103693590 0.22530000 0.077874576 0.21531639 1.0000000 1.966991
#> 41: 0.010722078 0.33776667 0.006294304 0.35077573 1.0000000 2.270037
#> 42: 30.000000000 0.55923333 0.005301487 0.56156486 1.0000000 2.740291
#> 43: 0.006229871 0.23093333 0.004661971 0.25237654 1.0000000 2.423790
#> 44: 0.002756447 0.20110000 0.002085738 0.22629021 1.0000000 2.161036
#> 45: 30.000000000 0.77860000 0.007310403 0.79181981 1.0000000 2.065713
#> 46: 0.041965155 0.41790000 0.012099942 0.44418366 1.0000000 1.763005
#> 47: 0.005912214 0.36410000 0.003552790 0.37709397 1.0000000 2.755200
#> 48: 30.000000000 0.70263333 0.004561251 0.70521133 1.0000000 2.642410
#> 49: 30.000000000 0.76936667 0.012481407 0.77448135 1.0000000 1.432588
#> 50: 0.007884476 0.02790000 0.007623490 0.03706278 1.0000000 2.287981
#> 51: 0.001975139 0.01156667 0.001941693 0.02047816 1.0000000 2.448673
#> 52: 0.013697468 0.06936667 0.013030558 0.07094849 1.0000000 3.065907
#> 53: 0.003811979 0.06773333 0.003585337 0.07825779 1.0000000 2.776919
#> 54: 0.003197359 0.08630000 0.002932087 0.09935284 1.0000000 2.557727
#> 55: 0.014902515 0.01756667 0.014508564 0.03128655 1.0000000 2.411884
#> 56: 0.002887489 0.13533333 0.002461805 0.13678567 1.0000000 2.003949
#> 57: 0.005396956 0.06396667 0.005034691 0.06871316 1.0000000 2.127642
#> 58: 0.015444308 0.04450000 0.014793650 0.04081369 1.0000000 1.978326
#> 59: 0.032638339 0.17626667 0.027413659 0.18981432 1.0000000 2.736872
#> 60: 30.000000000 0.57070000 0.005350482 0.56115445 1.0000000 2.940905
#> 61: 0.023097263 0.17430000 0.019657332 0.17067228 1.0000000 2.589266
#> 62: 0.004922621 0.16046667 0.004218802 0.18540041 1.0000000 3.002839
#> 63: 0.010326282 0.07083333 0.009658844 0.08373933 1.0000000 2.743208
#> 64: 0.027637201 0.11686667 0.025274379 0.09621464 1.0000000 2.391418
#> 65: 0.019427772 0.34556667 0.011549019 0.36203554 1.0000000 2.475686
#> 66: 0.009224850 0.05420000 0.008730319 0.04790721 1.0000000 1.827993
#> 67: 0.007990484 0.08710000 0.007043304 0.10560283 1.0000000 1.880336
#> 68: 0.054323446 0.07786667 0.049549089 0.09209706 1.0000000 2.213005
#> 69: 0.008297512 0.29680000 0.005151240 0.30315714 1.0000000 1.955457
#> 70: 0.028380166 0.37660000 0.016287291 0.38712847 1.0000000 2.680251
#> 71: 0.003121891 0.06380000 0.002908151 0.06403699 1.0000000 1.932432
#> 72: 0.015278400 0.26503333 0.010185821 0.26943207 1.0000000 1.909176
#> 73: 0.007000949 0.19893333 0.005440592 0.19547452 1.0000000 1.966440
#> 74: 0.010133991 0.19443333 0.008351180 0.18112340 1.0000000 2.324659
#> 75: 0.022055538 0.08350000 0.020776435 0.07624990 1.0000000 2.769539
#> 76: 0.007029613 0.29376667 0.004287339 0.29150899 1.0000000 1.769006
#> 77: 0.013769074 0.02206667 0.013254560 0.03556904 1.0000000 1.937726
#> 78: 0.047179141 0.14253333 0.037914493 0.15699796 1.0000000 1.723879
#> 79: 0.045215408 0.05843333 0.043031281 0.06820615 1.0000000 2.962191
#> 80: 0.042486343 0.29903333 0.025152816 0.32334398 1.0000000 1.984697
#> 81: 30.000000000 0.65316667 0.019245011 0.65209837 1.0000000 1.796886
#> 82: 30.000000000 0.59670000 0.055689068 0.60914083 1.0000000 2.665200
#> 83: 0.295080096 0.30650000 0.158198620 0.34093110 1.0000000 1.837149
#> 84: 0.413743153 0.41173333 0.206332658 0.42342449 1.0000000 2.696824
#> 85: 30.000000000 0.65686667 0.129212028 0.65883941 1.0000000 2.006733
#> 86: 30.000000000 0.56523333 0.085602158 0.58627595 1.0000000 3.117706
#> 87: 30.000000000 0.68853333 0.149067206 0.70263542 1.0000000 3.578535
#> 88: 30.000000000 0.52300000 0.102208367 0.52064083 1.0000000 2.321359
#> 89: 30.000000000 0.61000000 0.256158972 0.61685311 1.0000000 2.023378
#> 90: 0.236075692 0.30246667 0.135223132 0.32473738 1.0000000 1.881323
#> 91: 30.000000000 0.52713333 0.013128583 0.54530841 1.0000000 1.733740
#> 92: 0.070162438 0.22003333 0.050619652 0.24695917 1.0000000 2.086104
#> 93: 0.010695136 0.21133333 0.008294007 0.20699055 1.0000000 2.101833
#> 94: 0.025509994 0.18053333 0.021456873 0.17635164 1.0000000 2.513797
#> 95: 0.102279380 0.20620000 0.075806992 0.23335970 1.0000000 2.099067
#> 96: 0.039032319 0.28623333 0.029513143 0.29115866 1.0000000 3.122947
#> 97: 0.012891906 0.08013333 0.011778656 0.08958619 1.0000000 2.186258
#> 98: 0.045034344 0.20156667 0.035484367 0.18949638 1.0000000 1.998935
#> 99: 0.150209032 0.07513333 0.137152296 0.09235428 1.0000000 2.245643
#> 100: 0.027440547 0.08603333 0.024485958 0.09662172 1.0000000 1.884916
#> IC50 E Max EC50 E Inf E0 h RV
#> RV R2 RV p Value RV Rss RV Sd Avg Fit Type RV
#> <num> <num> <num> <num> <char>
#> 1: 0.9924695 3.705769e-08 0.0027788222 0.02424423 DRC3pHillFitModelFixS0
#> 2: 0.9958511 4.600131e-09 0.0021823404 0.02195104 DRC3pHillFitModelFixS0
#> 3: 0.9918874 4.809026e-08 0.0011623407 0.02315049 DRC3pHillFitModelFixS0
#> 4: 0.9788260 1.381366e-06 0.0018580999 0.02433754 DRC3pHillFitModelFixS0
#> 5: 0.9978624 4.515583e-10 0.0006002563 0.02914251 DRC3pHillFitModelFixS0
#> 6: 0.9622053 1.049565e-05 0.0010089336 0.03095134 DRC3pHillFitModelFixS0
#> 7: 0.9796018 1.212200e-06 0.0021497125 0.02851709 DRC3pHillFitModelFixS0
#> 8: 0.9917851 5.024614e-08 0.0022433269 0.02120201 DRC3pHillFitModelFixS0
#> 9: 0.9894868 1.191422e-07 0.0014484927 0.02368805 DRC3pHillFitModelFixS0
#> 10: 0.9985658 1.117095e-10 0.0020514821 0.02467602 DRC3pHillFitModelFixS0
#> 11: 0.9767620 1.912923e-06 0.0042266456 0.02026923 DRC3pHillFitModelFixS0
#> 12: 0.9952426 7.426431e-09 0.0021879035 0.02564250 DRC3pHillFitModelFixS0
#> 13: 0.8541039 1.186186e-03 0.0023608040 0.03624754 DRC3pHillFitModelFixS0
#> 14: 0.9832682 6.059013e-07 0.0010166387 0.02462014 DRC3pHillFitModelFixS0
#> 15: 0.9725466 3.428366e-06 0.0013962272 0.02581034 DRC3pHillFitModelFixS0
#> 16: 0.9569420 1.656493e-05 0.0022229434 0.02491576 DRC3pHillFitModelFixS0
#> 17: 0.9968137 1.825950e-09 0.0006398224 0.03482572 DRC3pHillFitModelFixS0
#> 18: 0.9984890 1.340914e-10 0.0008475955 0.02606777 DRC3pHillFitModelFixS0
#> 19: 0.9917990 4.995008e-08 0.0014512290 0.02352835 DRC3pHillFitModelFixS0
#> 20: 0.9901512 9.480595e-08 0.0014125688 0.02706624 DRC3pHillFitModelFixS0
#> 21: 0.9949255 9.308666e-09 0.0007114611 0.02403599 DRC3pHillFitModelFixS0
#> 22: 0.9962628 3.190785e-09 0.0015119310 0.02698012 DRC3pHillFitModelFixS0
#> 23: 0.9909905 6.941415e-08 0.0023665643 0.02577172 DRC3pHillFitModelFixS0
#> 24: 0.9973294 9.843622e-10 0.0006363358 0.02525688 DRC3pHillFitModelFixS0
#> 25: 0.9934571 2.265652e-08 0.0013783062 0.02269828 DRC3pHillFitModelFixS0
#> 26: 0.9960204 3.976072e-09 0.0011374563 0.02402262 DRC3pHillFitModelFixS0
#> 27: 0.0000000 4.979239e-01 0.0029436207 0.02620160 DRCConstantFitResult
#> 28: 0.9951205 8.115446e-09 0.0027937482 0.02903764 DRC3pHillFitModelFixS0
#> 29: 0.9729143 3.270314e-06 0.0015619403 0.02427360 DRC3pHillFitModelFixS0
#> 30: 0.9935786 2.121800e-08 0.0015913349 0.02469797 DRC3pHillFitModelFixS0
#> 31: 0.9253169 1.138357e-04 0.0040117584 0.02546309 DRC3pHillFitModelFixS0
#> 32: 0.9442965 4.079327e-05 0.0022454435 0.03159417 DRC3pHillFitModelFixS0
#> 33: 0.9908466 7.337283e-08 0.0007607914 0.02897195 DRC3pHillFitModelFixS0
#> 34: 0.8671881 8.537470e-04 0.0032197577 0.02385616 DRC3pHillFitModelFixS0
#> 35: 0.9971479 1.238942e-09 0.0004630470 0.02145847 DRC3pHillFitModelFixS0
#> 36: 0.9613882 1.131147e-05 0.0018341727 0.02696312 DRC3pHillFitModelFixS0
#> 37: 0.0000000 3.003192e-01 0.0034434491 0.02670075 DRCConstantFitResult
#> 38: 0.9917875 5.019502e-08 0.0015741830 0.02216258 DRC3pHillFitModelFixS0
#> 39: 0.9367858 6.351119e-05 0.0023356139 0.02237141 DRC3pHillFitModelFixS0
#> 40: 0.9976196 6.580954e-10 0.0026451685 0.03512306 DRC3pHillFitModelFixS0
#> 41: 0.9991870 1.532058e-11 0.0004309408 0.02583750 DRC3pHillFitModelFixS0
#> 42: 0.9951004 8.232852e-09 0.0011916253 0.02329129 DRC3pHillFitModelFixS0
#> 43: 0.9933838 2.355796e-08 0.0039254874 0.02481987 DRC3pHillFitModelFixS0
#> 44: 0.9941359 1.544166e-08 0.0022236840 0.02302050 DRC3pHillFitModelFixS0
#> 45: 0.9820954 7.680224e-07 0.0010163372 0.02911082 DRC3pHillFitModelFixS0
#> 46: 0.9967096 2.043397e-09 0.0014121632 0.02750852 DRC3pHillFitModelFixS0
#> 47: 0.9964623 2.633342e-09 0.0013740389 0.01788683 DRC3pHillFitModelFixS0
#> 48: 0.9930514 2.796599e-08 0.0007360079 0.03663836 DRC3pHillFitModelFixS0
#> 49: 0.9629959 9.747072e-06 0.0024229473 0.01589380 DRC3pHillFitModelFixS0
#> 50: 0.9995991 1.290124e-12 0.0004814205 0.02605429 DRC3pHillFitModelFixS0
#> 51: 0.9992976 9.185549e-12 0.0004198723 0.01347179 DRC3pHillFitModelFixS0
#> 52: 0.9982225 2.367642e-10 0.0023752601 0.02166174 DRC3pHillFitModelFixS0
#> 53: 0.9969366 1.591078e-09 0.0027166839 0.02379256 DRC3pHillFitModelFixS0
#> 54: 0.9990998 2.188336e-11 0.0006322521 0.02440520 DRC3pHillFitModelFixS0
#> 55: 0.9989330 3.968447e-11 0.0015443091 0.02854761 DRC3pHillFitModelFixS0
#> 56: 0.9940489 1.625854e-08 0.0030714525 0.02768624 DRC3pHillFitModelFixS0
#> 57: 0.9977338 5.540498e-10 0.0021463145 0.02021322 DRC3pHillFitModelFixS0
#> 58: 0.9993449 7.196834e-12 0.0008883295 0.02920943 DRC3pHillFitModelFixS0
#> 59: 0.9994655 3.530406e-12 0.0006289186 0.02246907 DRC3pHillFitModelFixS0
#> 60: 0.9878645 1.968793e-07 0.0028158117 0.02061972 DRC3pHillFitModelFixS0
#> 61: 0.9980176 3.468423e-10 0.0024284335 0.02328919 DRC3pHillFitModelFixS0
#> 62: 0.9978019 4.979588e-10 0.0016845191 0.02727108 DRC3pHillFitModelFixS0
#> 63: 0.9966324 2.216266e-09 0.0042541545 0.02529924 DRC3pHillFitModelFixS0
#> 64: 0.9979799 3.705174e-10 0.0027829406 0.02494556 DRC3pHillFitModelFixS0
#> 65: 0.9965915 2.311928e-09 0.0021365407 0.02789728 DRC3pHillFitModelFixS0
#> 66: 0.9990550 2.594026e-11 0.0010823145 0.03555896 DRC3pHillFitModelFixS0
#> 67: 0.9988034 5.926379e-11 0.0011411900 0.02594352 DRC3pHillFitModelFixS0
#> 68: 0.9983842 1.695655e-10 0.0024649969 0.02468871 DRC3pHillFitModelFixS0
#> 69: 0.9958787 4.494010e-09 0.0021801892 0.02364677 DRC3pHillFitModelFixS0
#> 70: 0.9975327 7.461140e-10 0.0015856291 0.02115656 DRC3pHillFitModelFixS0
#> 71: 0.9991981 1.460497e-11 0.0005404075 0.02845357 DRC3pHillFitModelFixS0
#> 72: 0.9995183 2.452621e-12 0.0003467009 0.02094491 DRC3pHillFitModelFixS0
#> 73: 0.9994474 3.967682e-12 0.0004025462 0.03261254 DRC3pHillFitModelFixS0
#> 74: 0.9966253 2.232695e-09 0.0029765716 0.01687243 DRC3pHillFitModelFixS0
#> 75: 0.9992905 9.514306e-12 0.0010395275 0.02890447 DRC3pHillFitModelFixS0
#> 76: 0.9973898 9.085852e-10 0.0012150473 0.02575115 DRC3pHillFitModelFixS0
#> 77: 0.9990756 2.401496e-11 0.0012638360 0.02401299 DRC3pHillFitModelFixS0
#> 78: 0.9986513 9.008741e-11 0.0015699934 0.03358047 DRC3pHillFitModelFixS0
#> 79: 0.9993880 5.670183e-12 0.0010056258 0.02405125 DRC3pHillFitModelFixS0
#> 80: 0.9960406 3.905880e-09 0.0029102882 0.03048010 DRC3pHillFitModelFixS0
#> 81: 0.9981400 2.775246e-10 0.0003485312 0.02875185 DRC3pHillFitModelFixS0
#> 82: 0.9969579 1.552798e-09 0.0009178606 0.02807435 DRC3pHillFitModelFixS0
#> 83: 0.9963409 2.963407e-09 0.0027780381 0.02321208 DRC3pHillFitModelFixS0
#> 84: 0.9985293 1.219970e-10 0.0009193400 0.03321846 DRC3pHillFitModelFixS0
#> 85: 0.9949262 9.303663e-09 0.0010726159 0.02970061 DRC3pHillFitModelFixS0
#> 86: 0.9948828 9.585348e-09 0.0017207801 0.02613007 DRC3pHillFitModelFixS0
#> 87: 0.9913418 6.039404e-08 0.0016026034 0.03144202 DRC3pHillFitModelFixS0
#> 88: 0.9918926 4.798189e-08 0.0037064480 0.02837621 DRC3pHillFitModelFixS0
#> 89: 0.9948254 9.967103e-09 0.0013976276 0.03160124 DRC3pHillFitModelFixS0
#> 90: 0.9969943 1.488693e-09 0.0025492991 0.01994518 DRC3pHillFitModelFixS0
#> 91: 0.9968381 1.777626e-09 0.0009436559 0.02358830 DRC3pHillFitModelFixS0
#> 92: 0.9970699 1.361674e-09 0.0029342522 0.02633392 DRC3pHillFitModelFixS0
#> 93: 0.9960998 3.705262e-09 0.0032832350 0.02144606 DRC3pHillFitModelFixS0
#> 94: 0.9988743 4.786781e-11 0.0013274649 0.03026998 DRC3pHillFitModelFixS0
#> 95: 0.9968471 1.759891e-09 0.0035472702 0.02618347 DRC3pHillFitModelFixS0
#> 96: 0.9976141 6.634336e-10 0.0023287486 0.01817215 DRC3pHillFitModelFixS0
#> 97: 0.9990599 2.547129e-11 0.0011386370 0.02235921 DRC3pHillFitModelFixS0
#> 98: 0.9961207 3.636093e-09 0.0042739653 0.02298094 DRC3pHillFitModelFixS0
#> 99: 0.9988156 5.718652e-11 0.0018424204 0.03151223 DRC3pHillFitModelFixS0
#> 100: 0.9986615 8.773134e-11 0.0018446214 0.03335063 DRC3pHillFitModelFixS0
#> RV R2 RV p Value RV Rss RV Sd Avg Fit Type RV
convert_se_assay_to_custom_dt(se, "Metrics", output_table = "Metrics_raw")
#> r Id c Id GR Mean
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.472929759
#> 2: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.393219859
#> 3: G00004_drug_004_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.839327136
#> 4: G00005_drug_005_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.781708106
#> 5: G00006_drug_006_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.646759184
#> 6: G00007_drug_007_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.937436799
#> 7: G00008_drug_008_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.720542898
#> 8: G00009_drug_009_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.704849585
#> 9: G00010_drug_010_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.860814168
#> 10: G00011_drug_011_moa_B_72 CL00011_cellline_BA_tissue_x_26 0.207159460
#> 11: G00002_drug_002_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.710189522
#> 12: G00003_drug_003_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.332747901
#> 13: G00004_drug_004_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.922099383
#> 14: G00005_drug_005_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.808309237
#> 15: G00006_drug_006_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.866903473
#> 16: G00007_drug_007_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.836985050
#> 17: G00008_drug_008_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.791435957
#> 18: G00009_drug_009_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.491313620
#> 19: G00010_drug_010_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.763749516
#> 20: G00011_drug_011_moa_B_72 CL00012_cellline_CA_tissue_x_30 0.780650008
#> 21: G00002_drug_002_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.794248968
#> 22: G00003_drug_003_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.374827861
#> 23: G00004_drug_004_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.709167535
#> 24: G00005_drug_005_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.697104582
#> 25: G00006_drug_006_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.676875616
#> 26: G00007_drug_007_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.652414714
#> 27: G00008_drug_008_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.984385185
#> 28: G00009_drug_009_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.514432888
#> 29: G00010_drug_010_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.878482510
#> 30: G00011_drug_011_moa_B_72 CL00013_cellline_DA_tissue_x_34 0.634715550
#> 31: G00002_drug_002_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.858014876
#> 32: G00003_drug_003_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.909591493
#> 33: G00004_drug_004_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.864237280
#> 34: G00005_drug_005_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.939294715
#> 35: G00006_drug_006_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.669107225
#> 36: G00007_drug_007_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.876104175
#> 37: G00008_drug_008_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.987433333
#> 38: G00009_drug_009_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.752739905
#> 39: G00010_drug_010_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.857326327
#> 40: G00011_drug_011_moa_B_72 CL00014_cellline_EA_tissue_x_38 0.435872637
#> 41: G00002_drug_002_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.280017800
#> 42: G00003_drug_003_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.536315316
#> 43: G00004_drug_004_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.097480450
#> 44: G00005_drug_005_moa_A_72 CL00015_cellline_FA_tissue_x_42 -0.038391125
#> 45: G00006_drug_006_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.801673120
#> 46: G00007_drug_007_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.459163515
#> 47: G00008_drug_008_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.261931402
#> 48: G00009_drug_009_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.694250375
#> 49: G00010_drug_010_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.800908530
#> 50: G00011_drug_011_moa_B_72 CL00015_cellline_FA_tissue_x_42 -0.288561464
#> 51: G00002_drug_002_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.645509596
#> 52: G00003_drug_003_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.151209620
#> 53: G00004_drug_004_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.362400138
#> 54: G00005_drug_005_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.328454740
#> 55: G00006_drug_006_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.224809588
#> 56: G00007_drug_007_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.260281000
#> 57: G00008_drug_008_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.314141961
#> 58: G00009_drug_009_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.188230693
#> 59: G00010_drug_010_moa_A_72 CL00016_cellline_GB_tissue_y_46 0.177463519
#> 60: G00011_drug_011_moa_B_72 CL00016_cellline_GB_tissue_y_46 0.499202800
#> 61: G00002_drug_002_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.059329643
#> 62: G00003_drug_003_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.156760855
#> 63: G00004_drug_004_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.218107316
#> 64: G00005_drug_005_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.017982323
#> 65: G00006_drug_006_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.264938349
#> 66: G00007_drug_007_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.305037682
#> 67: G00008_drug_008_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.212954966
#> 68: G00009_drug_009_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.091984103
#> 69: G00010_drug_010_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.089668620
#> 70: G00011_drug_011_moa_B_72 CL00017_cellline_HB_tissue_y_50 0.334329487
#> 71: G00002_drug_002_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.501402843
#> 72: G00003_drug_003_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.077780973
#> 73: G00004_drug_004_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.131760019
#> 74: G00005_drug_005_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.093988826
#> 75: G00006_drug_006_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.125734009
#> 76: G00007_drug_007_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.003190178
#> 77: G00008_drug_008_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.286159124
#> 78: G00009_drug_009_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.112201368
#> 79: G00010_drug_010_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.005980476
#> 80: G00011_drug_011_moa_B_72 CL00018_cellline_IB_tissue_y_54 0.267043249
#> 81: G00002_drug_002_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.606827931
#> 82: G00003_drug_003_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.630511020
#> 83: G00004_drug_004_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.483973989
#> 84: G00005_drug_005_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.581204001
#> 85: G00006_drug_006_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.731518966
#> 86: G00007_drug_007_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.639612759
#> 87: G00008_drug_008_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.774175841
#> 88: G00009_drug_009_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.595786753
#> 89: G00010_drug_010_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.744384655
#> 90: G00011_drug_011_moa_B_72 CL00019_cellline_JB_tissue_z_58 0.449758703
#> 91: G00002_drug_002_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.418086223
#> 92: G00003_drug_003_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.203645096
#> 93: G00004_drug_004_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.132168662
#> 94: G00005_drug_005_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.024941265
#> 95: G00006_drug_006_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.249504542
#> 96: G00007_drug_007_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.176988967
#> 97: G00008_drug_008_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.264481101
#> 98: G00009_drug_009_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.077484203
#> 99: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.199150357
#> 100: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 -0.114813416
#> r Id c Id GR Mean
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> <num> <num> <num> <num> <num>
#> 1: 0.52707024 0.60484720 0.008956223 0.33660000 0.004512560
#> 2: 0.60678014 0.70277140 0.006591468 0.25136667 0.004714084
#> 3: 0.16067286 0.19050089 Inf 0.76383333 0.017152797
#> 4: 0.21829189 0.25018175 Inf 0.73936667 0.003425139
#> 5: 0.35324082 0.41393595 Inf 0.56643333 0.004372707
#> 6: 0.06256320 0.06575521 Inf 0.89593333 6.055622159
#> 7: 0.27945710 0.30997686 Inf 0.65743333 0.002559558
#> 8: 0.29515042 0.34870740 Inf 0.63046667 0.008778928
#> 9: 0.13918583 0.16273320 Inf 0.77656667 0.032779888
#> 10: 0.79284054 0.93195933 0.021403060 -0.24116667 0.025129204
#> 11: 0.28981048 0.33967455 Inf 0.65893333 0.005025942
#> 12: 0.66725210 0.76169198 0.003994252 0.17163333 0.003302060
#> 13: 0.07790062 0.09343051 Inf 0.88726667 0.008287858
#> 14: 0.19169076 0.22105147 Inf 0.79443333 0.003408721
#> 15: 0.13309653 0.15708142 Inf 0.82726667 0.008098714
#> 16: 0.16301495 0.18647466 Inf 0.79136667 0.003969114
#> 17: 0.20856404 0.24449577 Inf 0.67090000 0.027533368
#> 18: 0.50868638 0.60551778 0.014718394 0.30453333 0.010370991
#> 19: 0.23625048 0.28073456 Inf 0.67690000 0.011214419
#> 20: 0.21934999 0.26078562 Inf 0.70800000 0.008628168
#> 21: 0.20575103 0.24291610 Inf 0.68636667 0.018792763
#> 22: 0.62517214 0.72107940 0.004733541 0.24863333 0.003733333
#> 23: 0.29083246 0.34315973 Inf 0.57196667 0.019154852
#> 24: 0.30289542 0.35827349 Inf 0.56803333 0.015397125
#> 25: 0.32312438 0.38472189 Inf 0.57023333 0.007742051
#> 26: 0.34758529 0.41267609 Inf 0.50863333 0.011835446
#> 27: 0.01561481 0.01561481 Inf 0.97146667 0.000000000
#> 28: 0.48556711 0.56936523 0.034901667 0.22980000 0.022820133
#> 29: 0.12151749 0.14271246 Inf 0.82306667 0.024473312
#> 30: 0.36528445 0.43067820 Inf 0.51870000 0.007550572
#> 31: 0.14198512 0.16878024 Inf 0.80660000 0.007501824
#> 32: 0.09040851 0.10536618 Inf 0.82636667 0.038864061
#> 33: 0.13576272 0.15824641 Inf 0.76243333 0.038650933
#> 34: 0.06070529 0.07176469 Inf 0.91113333 0.020890672
#> 35: 0.33089278 0.39183474 Inf 0.59120000 0.005647023
#> 36: 0.12389583 0.14638273 Inf 0.78433333 0.021030163
#> 37: 0.01256667 0.01256667 Inf 0.97186667 0.000000000
#> 38: 0.24726009 0.29120537 Inf 0.61536667 0.024975182
#> 39: 0.14267367 0.16980694 Inf 0.81726667 0.008782943
#> 40: 0.56412736 0.63987995 0.083979077 -0.09190000 0.092656739
#> 41: 0.71998220 0.84636750 0.007532111 0.06133333 0.006931018
#> 42: 0.46368468 0.54490372 0.011313171 0.42486667 0.005539077
#> 43: 0.90251955 1.05310942 0.004804846 -0.15033333 0.005196465
#> 44: 1.03839112 1.14486626 0.002096183 -0.21590000 0.002402173
#> 45: 0.19832688 0.23289841 Inf 0.72833333 0.007472182
#> 46: 0.54083649 0.63547037 0.019685244 0.20183333 0.013344832
#> 47: 0.73806860 0.84884751 0.004278853 0.10913333 0.003823207
#> 48: 0.30574963 0.35592969 Inf 0.62720000 0.004699445
#> 49: 0.19909147 0.23175051 Inf 0.71623333 0.013054619
#> 50: 1.28856146 1.52231622 0.006501568 -0.76076667 0.009877882
#> 51: 1.64550960 1.81869399 0.001554925 -0.88523333 0.002461726
#> 52: 1.15120962 1.36693104 0.011295294 -0.63760000 0.014964922
#> 53: 1.36240014 1.58088594 0.003102882 -0.64316667 0.003627803
#> 54: 1.32845474 1.52484992 0.002821583 -0.59106667 0.003261246
#> 55: 1.22480959 1.44589294 0.011797654 -0.85010000 0.018211003
#> 56: 1.26028100 1.40891804 0.002124075 -0.44813333 0.002908819
#> 57: 1.31414196 1.53378544 0.004126866 -0.66630000 0.006208157
#> 58: 1.18823069 1.39705508 0.011541663 -0.74830000 0.019093562
#> 59: 0.82253648 0.96378586 0.025291861 -0.34083333 0.030462173
#> 60: 0.50079720 0.59001656 0.009069128 0.39763333 0.005532738
#> 61: 0.94067036 1.10926395 0.017069264 -0.40870000 0.021770780
#> 62: 1.15676086 1.35220803 0.003518715 -0.43993333 0.003926883
#> 63: 1.21810732 1.44505824 0.007845694 -0.68250000 0.011080523
#> 64: 1.01798232 1.19375008 0.020839662 -0.55216667 0.028935636
#> 65: 0.73506165 0.87121078 0.012275930 -0.04430000 0.012435379
#> 66: 1.30503768 1.53138485 0.006343314 -0.74286667 0.010860272
#> 67: 1.21295497 1.41975706 0.005422182 -0.63310000 0.008331080
#> 68: 0.90801590 1.04589054 0.039209092 -0.66776667 0.057979675
#> 69: 0.91033138 1.05593041 0.005013879 -0.13980000 0.005644554
#> 70: 0.66567051 0.78831518 0.017651636 0.01416667 0.017187956
#> 71: 1.50140284 1.69282924 0.002079722 -0.75150000 0.003379462
#> 72: 0.92221903 1.08549021 0.008896978 -0.26123333 0.011083282
#> 73: 1.13176002 1.31651313 0.004407585 -0.40610000 0.006019440
#> 74: 1.09398883 1.29535998 0.006947625 -0.41440000 0.009103145
#> 75: 1.12573401 1.32679092 0.016745695 -0.69520000 0.023147806
#> 76: 0.99680982 1.14178852 0.003824450 -0.20206667 0.004653230
#> 77: 1.28615912 1.51385999 0.009229506 -0.88796667 0.015867486
#> 78: 0.88779863 1.02895436 0.028449345 -0.53723333 0.043025854
#> 79: 1.00598048 1.16593241 0.034588147 -0.76266667 0.047602705
#> 80: 0.73295675 0.85892056 0.023671502 -0.19190000 0.026969054
#> 81: 0.39317207 0.46194732 0.053626857 0.41883333 0.019690231
#> 82: 0.36948898 0.42607970 0.087295888 0.31943333 0.056703027
#> 83: 0.51602601 0.57087256 0.143455577 -0.22873333 0.167033674
#> 84: 0.41879600 0.45743157 0.212648132 -0.02213333 0.212600715
#> 85: 0.26848103 0.30032538 0.344685074 0.42540000 0.131446499
#> 86: 0.36038724 0.40984406 0.117452572 0.26290000 0.086914958
#> 87: 0.22582416 0.25108633 Inf 0.48070000 0.150506549
#> 88: 0.40421325 0.45641866 0.126923290 0.18620000 0.104938005
#> 89: 0.25561534 0.27576952 0.482004214 0.34280000 0.262050505
#> 90: 0.55024130 0.61304737 0.120388567 -0.23676667 0.143651843
#> 91: 0.58191378 0.68366685 0.017638803 0.15233333 0.013459091
#> 92: 0.79635490 0.91959952 0.039776880 -0.45710000 0.052972634
#> 93: 1.13216866 1.33323831 0.006256750 -0.47600000 0.008730800
#> 94: 1.02494127 1.20800058 0.016682174 -0.54256667 0.022466542
#> 95: 0.75049546 0.85590610 0.058794620 -0.48653333 0.079484138
#> 96: 0.82301103 0.96481060 0.025824025 -0.31900000 0.030306953
#> 97: 1.26448110 1.49594653 0.008219032 -0.77343333 0.012547541
#> 98: 0.92251580 1.07425601 0.026077313 -0.49686667 0.037516853
#> 99: 0.80084964 0.89159948 0.096729600 -0.78626667 0.146270629
#> 100: 1.11481342 1.30596053 0.016239553 -0.76026667 0.026434030
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> <num> <num> <num> <num> <num> <num>
#> 1: 0.3651678148 1.0000000 1.9119007 0.9884406 1.660656e-07 0.0045303452
#> 2: 0.2663967900 1.0000000 2.2700932 0.9905292 8.267143e-08 0.0056700663
#> 3: 0.7669777183 1.0000000 3.1437068 0.9914280 5.831599e-08 0.0007996589
#> 4: 0.7468373651 1.0000000 3.3444924 0.9757902 2.207855e-06 0.0014589160
#> 5: 0.5776422640 1.0000000 3.7583023 0.9968734 1.709038e-09 0.0006971243
#> 6: 0.7767392076 1.0000000 0.2541701 0.7382169 9.179004e-03 0.0039751137
#> 7: 0.6856295469 1.0000000 2.2283677 0.9732050 3.149112e-06 0.0020708650
#> 8: 0.6122474630 1.0000000 2.2285708 0.9880579 1.861139e-07 0.0024924890
#> 9: 0.7754650425 1.0000000 2.2889985 0.9888129 1.480842e-07 0.0009916378
#> 10: -0.2226798163 1.0000000 2.2951127 0.9990488 2.654224e-11 0.0024404603
#> 11: 0.6470730550 1.0000000 2.8677996 0.9704197 4.451549e-06 0.0049211098
#> 12: 0.2295353843 1.0000000 3.2287691 0.9908815 7.239884e-08 0.0055504640
#> 13: 0.8985288362 1.0000000 5.0000000 0.8578698 1.082436e-03 0.0017311323
#> 14: 0.7779257424 1.0000000 5.0000000 0.9811907 9.126541e-07 0.0009519863
#> 15: 0.8271028214 1.0000000 2.2446169 0.9693003 5.069529e-06 0.0012425224
#> 16: 0.8069689420 1.0000000 2.1324423 0.9532749 2.205084e-05 0.0019540733
#> 17: 0.6734026973 1.0000000 2.0561031 0.9962473 3.237437e-09 0.0006692208
#> 18: 0.3158838755 1.0000000 2.8537073 0.9979296 4.037965e-10 0.0014073691
#> 19: 0.6786316274 1.0000000 2.6189994 0.9900052 9.981764e-08 0.0015756760
#> 20: 0.7126300563 1.0000000 2.7803450 0.9884951 1.633382e-07 0.0014199653
#> 21: 0.6972688823 1.0000000 2.2630422 0.9939342 1.738238e-08 0.0009119932
#> 22: 0.2671164396 1.0000000 3.2188686 0.9942855 1.410692e-08 0.0033809061
#> 23: 0.5707831317 1.0000000 2.2058511 0.9885236 1.619263e-07 0.0035039079
#> 24: 0.5679295931 1.0000000 2.2341289 0.9974080 8.865540e-10 0.0007253857
#> 25: 0.5830557926 1.0000000 3.0941181 0.9915566 5.531131e-08 0.0020546400
#> 26: 0.5234219383 1.0000000 2.5223390 0.9945689 1.180644e-08 0.0018728900
#> 27: 0.9843851852 0.9843852 0.0001000 0.0000000 5.051366e-01 0.0026667731
#> 28: 0.2627284849 1.0000000 1.7543375 0.9929829 2.894338e-08 0.0058346518
#> 29: 0.8134059397 1.0000000 2.0261477 0.9701477 4.596431e-06 0.0017203009
#> 30: 0.5300584965 1.0000000 2.2706141 0.9915850 5.466156e-08 0.0025042007
#> 31: 0.8175800194 1.0000000 2.9545779 0.9263136 1.086067e-04 0.0047546911
#> 32: 0.8497191486 1.0000000 5.0000000 0.9414806 4.847844e-05 0.0028277725
#> 33: 0.7745509842 1.0000000 5.0000000 0.9905919 8.077212e-08 0.0009703665
#> 34: 0.9091685072 1.0000000 5.0000000 0.8703307 7.851092e-04 0.0036147863
#> 35: 0.5909223718 1.0000000 3.3653065 0.9965291 2.463576e-09 0.0007708945
#> 36: 0.8144193534 1.0000000 3.2484642 0.9602404 1.253272e-05 0.0023079249
#> 37: 0.9874333333 0.9874333 0.0001000 0.0000000 5.226792e-01 0.0045005377
#> 38: 0.6190909106 1.0000000 5.0000000 0.9916347 5.354032e-08 0.0021490509
#> 39: 0.8126203033 1.0000000 2.8923837 0.9340415 7.369655e-05 0.0030096935
#> 40: -0.1100555561 1.0000000 2.0231247 0.9954539 6.335023e-09 0.0101608866
#> 41: 0.0843948493 1.0000000 2.2228625 0.9989540 3.700785e-11 0.0011299281
#> 42: 0.4280422001 1.0000000 2.7144943 0.9939185 1.754023e-08 0.0025486690
#> 43: -0.1044494537 1.0000000 2.4212065 0.9902549 9.135969e-08 0.0134618257
#> 44: -0.1620560072 1.0000000 2.0604060 0.9892455 1.289925e-07 0.0102617483
#> 45: 0.7451155399 1.0000000 2.0612207 0.9805388 1.028230e-06 0.0016676158
#> 46: 0.2444903289 1.0000000 1.7269837 0.9955545 5.857477e-09 0.0035994749
#> 47: 0.1316629628 1.0000000 2.7142277 0.9946978 1.085451e-08 0.0041780160
#> 48: 0.6307693263 1.0000000 2.6162346 0.9927082 3.310784e-08 0.0012196886
#> 49: 0.7222776333 1.0000000 1.3911231 0.9644174 8.498288e-06 0.0035483729
#> 50: -0.7215144153 1.0000000 2.1356334 0.9986787 8.385582e-11 0.0054197260
#> 51: -0.8445230124 1.0000000 2.1530486 0.9970059 1.468626e-09 0.0074471434
#> 52: -0.6348290617 1.0000000 2.9134838 0.9975549 7.227836e-10 0.0105548724
#> 53: -0.5906663271 1.0000000 4.9901264 0.9835173 5.749117e-07 0.0479741017
#> 54: -0.5306044465 1.0000000 4.9947313 0.9909207 7.131558e-08 0.0204750192
#> 55: -0.7932565672 1.0000000 2.1890242 0.9987491 6.923104e-11 0.0064150301
#> 56: -0.4405596014 1.0000000 2.0096850 0.9868501 2.607523e-07 0.0214141959
#> 57: -0.6475910270 1.0000000 2.0345801 0.9915706 5.499090e-08 0.0270484156
#> 58: -0.7531963509 1.0000000 1.8253213 0.9987855 6.243166e-11 0.0057202466
#> 59: -0.3102371436 1.0000000 2.5952204 0.9989539 3.702390e-11 0.0032347548
#> 60: 0.3824493623 1.0000000 2.9294992 0.9857446 3.458839e-07 0.0066776424
#> 61: -0.4169392990 1.0000000 2.4926426 0.9974568 8.294838e-10 0.0090820977
#> 62: -0.3641218697 1.0000000 4.9850173 0.9908614 7.295866e-08 0.0208479700
#> 63: -0.6541862131 1.0000000 2.4231874 0.9914850 5.697009e-08 0.0358041319
#> 64: -0.6074320061 1.0000000 2.4227680 0.9960819 3.765019e-09 0.0174257673
#> 65: -0.0153061841 1.0000000 2.3365273 0.9964806 2.586138e-09 0.0056269403
#> 66: -0.7689648974 1.0000000 1.7320650 0.9970436 1.404914e-09 0.0123458770
#> 67: -0.5835770177 1.0000000 1.8007551 0.9976480 6.309898e-10 0.0073846724
#> 68: -0.6255619766 1.0000000 2.0742923 0.9975373 7.412210e-10 0.0119795999
#> 69: -0.1277776181 1.0000000 1.9207939 0.9938926 1.780359e-08 0.0087658850
#> 70: 0.0342563614 1.0000000 2.6661846 0.9973400 9.707612e-10 0.0042664707
#> 71: -0.7476426517 1.0000000 1.8834936 0.9984594 1.435180e-10 0.0039640590
#> 72: -0.2532259879 1.0000000 1.8648542 0.9995596 1.792360e-12 0.0009511982
#> 73: -0.4137519625 1.0000000 1.9345991 0.9993732 6.163698e-12 0.0014555916
#> 74: -0.4443998175 1.0000000 2.3534208 0.9951423 7.989316e-09 0.0137384037
#> 75: -0.7126817181 1.0000000 2.7365478 0.9986032 1.018578e-10 0.0071007044
#> 76: -0.2065860191 1.0000000 1.7631520 0.9967875 1.879027e-09 0.0045316079
#> 77: -0.8438328827 1.0000000 1.8245692 0.9973253 9.896588e-10 0.0137058624
#> 78: -0.5033105133 1.0000000 1.6835691 0.9980112 3.507995e-10 0.0074336916
#> 79: -0.7350666349 1.0000000 2.8313491 0.9990251 2.892854e-11 0.0055864178
#> 80: -0.1438326892 1.0000000 1.9386164 0.9958942 4.434905e-09 0.0087060442
#> 81: 0.4170287342 1.0000000 1.7926586 0.9981406 2.772138e-10 0.0009814830
#> 82: 0.3413600699 1.0000000 2.6605690 0.9970120 1.458224e-09 0.0025565632
#> 83: -0.1599302533 1.0000000 1.8237894 0.9955606 5.829534e-09 0.0104168368
#> 84: 0.0002979208 1.0000000 2.6726325 0.9985093 1.279117e-10 0.0027912514
#> 85: 0.4295060402 1.0000000 2.0321759 0.9950986 8.243686e-09 0.0029000027
#> 86: 0.3003216477 1.0000000 3.0484446 0.9946346 1.131362e-08 0.0051502481
#> 87: 0.5048265847 1.0000000 3.5683198 0.9917107 5.185758e-08 0.0042469987
#> 88: 0.1831084883 1.0000000 2.3975662 0.9924392 3.758273e-08 0.0100206531
#> 89: 0.3552684841 1.0000000 2.0342894 0.9950033 8.818716e-09 0.0038048777
#> 90: -0.1933830016 1.0000000 1.8507842 0.9967431 1.971582e-09 0.0085515416
#> 91: 0.1860626932 1.0000000 1.7209131 0.9966220 2.240260e-09 0.0032422970
#> 92: -0.4013139858 1.0000000 2.0567782 0.9965388 2.439530e-09 0.0120338036
#> 93: -0.4866785556 1.0000000 2.0400478 0.9952028 7.646630e-09 0.0143425595
#> 94: -0.5517780648 1.0000000 2.4980285 0.9985723 1.099614e-10 0.0059898596
#> 95: -0.4303883285 1.0000000 2.0596328 0.9969133 1.633858e-09 0.0120169616
#> 96: -0.3098387168 1.0000000 3.0125648 0.9977677 5.256069e-10 0.0074113065
#> 97: -0.7490788673 1.0000000 2.1640592 0.9987682 6.560411e-11 0.0055870262
#> 98: -0.5239352601 1.0000000 1.9707233 0.9955609 5.828304e-09 0.0174009206
#> 99: -0.7443040083 1.0000000 2.2046853 0.9985705 1.104466e-10 0.0081610637
#> 100: -0.7340189608 1.0000000 1.8543083 0.9987249 7.403286e-11 0.0064842414
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> GR Sd Avg Fit Type GR maxlog10Concentration N Conc Fit Source
#> <num> <char> <num> <int> <char>
#> 1: 0.03203268 DRC3pHillFitModelFixS0 1 9 gDR
#> 2: 0.03075240 DRC3pHillFitModelFixS0 1 9 gDR
#> 3: 0.02000573 DRC3pHillFitModelFixS0 1 9 gDR
#> 4: 0.02214360 DRC3pHillFitModelFixS0 1 9 gDR
#> 5: 0.03066180 DRC3pHillFitModelFixS0 1 9 gDR
#> 6: 0.02346065 DRC3pHillFitModelFixS0 1 9 gDR
#> 7: 0.02679197 DRC3pHillFitModelFixS0 1 9 gDR
#> 8: 0.01983125 DRC3pHillFitModelFixS0 1 9 gDR
#> 9: 0.01910174 DRC3pHillFitModelFixS0 1 9 gDR
#> 10: 0.07130873 DRC3pHillFitModelFixS0 1 9 gDR
#> 11: 0.02101516 DRC3pHillFitModelFixS0 1 9 gDR
#> 12: 0.03850179 DRC3pHillFitModelFixS0 1 9 gDR
#> 13: 0.03205436 DRC3pHillFitModelFixS0 1 9 gDR
#> 14: 0.02326291 DRC3pHillFitModelFixS0 1 9 gDR
#> 15: 0.02352653 DRC3pHillFitModelFixS0 1 9 gDR
#> 16: 0.02344649 DRC3pHillFitModelFixS0 1 9 gDR
#> 17: 0.03340578 DRC3pHillFitModelFixS0 1 9 gDR
#> 18: 0.03448935 DRC3pHillFitModelFixS0 1 9 gDR
#> 19: 0.02377445 DRC3pHillFitModelFixS0 1 9 gDR
#> 20: 0.02630609 DRC3pHillFitModelFixS0 1 9 gDR
#> 21: 0.02570997 DRC3pHillFitModelFixS0 1 9 gDR
#> 22: 0.03926750 DRC3pHillFitModelFixS0 1 9 gDR
#> 23: 0.02824974 DRC3pHillFitModelFixS0 1 9 gDR
#> 24: 0.02856021 DRC3pHillFitModelFixS0 1 9 gDR
#> 25: 0.02557931 DRC3pHillFitModelFixS0 1 9 gDR
#> 26: 0.02875531 DRC3pHillFitModelFixS0 1 9 gDR
#> 27: 0.02503984 DRCConstantFitResult 1 9 gDR
#> 28: 0.03690901 DRC3pHillFitModelFixS0 1 9 gDR
#> 29: 0.02418509 DRC3pHillFitModelFixS0 1 9 gDR
#> 30: 0.02944348 DRC3pHillFitModelFixS0 1 9 gDR
#> 31: 0.02872952 DRC3pHillFitModelFixS0 1 9 gDR
#> 32: 0.03452733 DRC3pHillFitModelFixS0 1 9 gDR
#> 33: 0.03283285 DRC3pHillFitModelFixS0 1 9 gDR
#> 34: 0.02600261 DRC3pHillFitModelFixS0 1 9 gDR
#> 35: 0.02690396 DRC3pHillFitModelFixS0 1 9 gDR
#> 36: 0.03016809 DRC3pHillFitModelFixS0 1 9 gDR
#> 37: 0.02836629 DRCConstantFitResult 1 9 gDR
#> 38: 0.02649059 DRC3pHillFitModelFixS0 1 9 gDR
#> 39: 0.02525543 DRC3pHillFitModelFixS0 1 9 gDR
#> 40: 0.05432540 DRC3pHillFitModelFixS0 1 9 gDR
#> 41: 0.04268871 DRC3pHillFitModelFixS0 1 9 gDR
#> 42: 0.03167032 DRC3pHillFitModelFixS0 1 9 gDR
#> 43: 0.04581144 DRC3pHillFitModelFixS0 1 9 gDR
#> 44: 0.04712220 DRC3pHillFitModelFixS0 1 9 gDR
#> 45: 0.03663539 DRC3pHillFitModelFixS0 1 9 gDR
#> 46: 0.04114510 DRC3pHillFitModelFixS0 1 9 gDR
#> 47: 0.02957059 DRC3pHillFitModelFixS0 1 9 gDR
#> 48: 0.04836989 DRC3pHillFitModelFixS0 1 9 gDR
#> 49: 0.01995472 DRC3pHillFitModelFixS0 1 9 gDR
#> 50: 0.09569389 DRC3pHillFitModelFixS0 1 9 gDR
#> 51: 0.05883646 DRC3pHillFitModelFixS0 1 9 gDR
#> 52: 0.05621152 DRC3pHillFitModelFixS0 1 9 gDR
#> 53: 0.06787391 DRC3pHillFitModelFixS0 1 9 gDR
#> 54: 0.06158907 DRC3pHillFitModelFixS0 1 9 gDR
#> 55: 0.07877147 DRC3pHillFitModelFixS0 1 9 gDR
#> 56: 0.06417974 DRC3pHillFitModelFixS0 1 9 gDR
#> 57: 0.06360624 DRC3pHillFitModelFixS0 1 9 gDR
#> 58: 0.08699730 DRC3pHillFitModelFixS0 1 9 gDR
#> 59: 0.03924611 DRC3pHillFitModelFixS0 1 9 gDR
#> 60: 0.02995868 DRC3pHillFitModelFixS0 1 9 gDR
#> 61: 0.04815310 DRC3pHillFitModelFixS0 1 9 gDR
#> 62: 0.05756475 DRC3pHillFitModelFixS0 1 9 gDR
#> 63: 0.05772902 DRC3pHillFitModelFixS0 1 9 gDR
#> 64: 0.05544735 DRC3pHillFitModelFixS0 1 9 gDR
#> 65: 0.04812444 DRC3pHillFitModelFixS0 1 9 gDR
#> 66: 0.10139524 DRC3pHillFitModelFixS0 1 9 gDR
#> 67: 0.06146191 DRC3pHillFitModelFixS0 1 9 gDR
#> 68: 0.05594040 DRC3pHillFitModelFixS0 1 9 gDR
#> 69: 0.04122973 DRC3pHillFitModelFixS0 1 9 gDR
#> 70: 0.03674990 DRC3pHillFitModelFixS0 1 9 gDR
#> 71: 0.07586112 DRC3pHillFitModelFixS0 1 9 gDR
#> 72: 0.04007412 DRC3pHillFitModelFixS0 1 9 gDR
#> 73: 0.06975153 DRC3pHillFitModelFixS0 1 9 gDR
#> 74: 0.03442655 DRC3pHillFitModelFixS0 1 9 gDR
#> 75: 0.06771926 DRC3pHillFitModelFixS0 1 9 gDR
#> 76: 0.04856655 DRC3pHillFitModelFixS0 1 9 gDR
#> 77: 0.06455336 DRC3pHillFitModelFixS0 1 9 gDR
#> 78: 0.06514096 DRC3pHillFitModelFixS0 1 9 gDR
#> 79: 0.04920195 DRC3pHillFitModelFixS0 1 9 gDR
#> 80: 0.05402095 DRC3pHillFitModelFixS0 1 9 gDR
#> 81: 0.04906576 DRC3pHillFitModelFixS0 1 9 gDR
#> 82: 0.04751873 DRC3pHillFitModelFixS0 1 9 gDR
#> 83: 0.04074026 DRC3pHillFitModelFixS0 1 9 gDR
#> 84: 0.05740278 DRC3pHillFitModelFixS0 1 9 gDR
#> 85: 0.04942568 DRC3pHillFitModelFixS0 1 9 gDR
#> 86: 0.04407493 DRC3pHillFitModelFixS0 1 9 gDR
#> 87: 0.05235831 DRC3pHillFitModelFixS0 1 9 gDR
#> 88: 0.04841497 DRC3pHillFitModelFixS0 1 9 gDR
#> 89: 0.05300916 DRC3pHillFitModelFixS0 1 9 gDR
#> 90: 0.03421832 DRC3pHillFitModelFixS0 1 9 gDR
#> 91: 0.04289095 DRC3pHillFitModelFixS0 1 9 gDR
#> 92: 0.05008110 DRC3pHillFitModelFixS0 1 9 gDR
#> 93: 0.04267612 DRC3pHillFitModelFixS0 1 9 gDR
#> 94: 0.06048658 DRC3pHillFitModelFixS0 1 9 gDR
#> 95: 0.05057676 DRC3pHillFitModelFixS0 1 9 gDR
#> 96: 0.03418831 DRC3pHillFitModelFixS0 1 9 gDR
#> 97: 0.04674118 DRC3pHillFitModelFixS0 1 9 gDR
#> 98: 0.04602459 DRC3pHillFitModelFixS0 1 9 gDR
#> 99: 0.06333498 DRC3pHillFitModelFixS0 1 9 gDR
#> 100: 0.07007818 DRC3pHillFitModelFixS0 1 9 gDR
#> GR Sd Avg Fit Type GR maxlog10Concentration N Conc Fit Source
#> Gnumber Drug Name Drug MOA Duration Clid Cell Line Name Tissue
#> <char> <char> <char> <num> <char> <char> <char>
#> 1: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 2: G00003 drug_003 moa_A 72 CL00011 cellline_BA tissue_x
#> 3: G00004 drug_004 moa_A 72 CL00011 cellline_BA tissue_x
#> 4: G00005 drug_005 moa_A 72 CL00011 cellline_BA tissue_x
#> 5: G00006 drug_006 moa_A 72 CL00011 cellline_BA tissue_x
#> 6: G00007 drug_007 moa_A 72 CL00011 cellline_BA tissue_x
#> 7: G00008 drug_008 moa_A 72 CL00011 cellline_BA tissue_x
#> 8: G00009 drug_009 moa_A 72 CL00011 cellline_BA tissue_x
#> 9: G00010 drug_010 moa_A 72 CL00011 cellline_BA tissue_x
#> 10: G00011 drug_011 moa_B 72 CL00011 cellline_BA tissue_x
#> 11: G00002 drug_002 moa_A 72 CL00012 cellline_CA tissue_x
#> 12: G00003 drug_003 moa_A 72 CL00012 cellline_CA tissue_x
#> 13: G00004 drug_004 moa_A 72 CL00012 cellline_CA tissue_x
#> 14: G00005 drug_005 moa_A 72 CL00012 cellline_CA tissue_x
#> 15: G00006 drug_006 moa_A 72 CL00012 cellline_CA tissue_x
#> 16: G00007 drug_007 moa_A 72 CL00012 cellline_CA tissue_x
#> 17: G00008 drug_008 moa_A 72 CL00012 cellline_CA tissue_x
#> 18: G00009 drug_009 moa_A 72 CL00012 cellline_CA tissue_x
#> 19: G00010 drug_010 moa_A 72 CL00012 cellline_CA tissue_x
#> 20: G00011 drug_011 moa_B 72 CL00012 cellline_CA tissue_x
#> 21: G00002 drug_002 moa_A 72 CL00013 cellline_DA tissue_x
#> 22: G00003 drug_003 moa_A 72 CL00013 cellline_DA tissue_x
#> 23: G00004 drug_004 moa_A 72 CL00013 cellline_DA tissue_x
#> 24: G00005 drug_005 moa_A 72 CL00013 cellline_DA tissue_x
#> 25: G00006 drug_006 moa_A 72 CL00013 cellline_DA tissue_x
#> 26: G00007 drug_007 moa_A 72 CL00013 cellline_DA tissue_x
#> 27: G00008 drug_008 moa_A 72 CL00013 cellline_DA tissue_x
#> 28: G00009 drug_009 moa_A 72 CL00013 cellline_DA tissue_x
#> 29: G00010 drug_010 moa_A 72 CL00013 cellline_DA tissue_x
#> 30: G00011 drug_011 moa_B 72 CL00013 cellline_DA tissue_x
#> 31: G00002 drug_002 moa_A 72 CL00014 cellline_EA tissue_x
#> 32: G00003 drug_003 moa_A 72 CL00014 cellline_EA tissue_x
#> 33: G00004 drug_004 moa_A 72 CL00014 cellline_EA tissue_x
#> 34: G00005 drug_005 moa_A 72 CL00014 cellline_EA tissue_x
#> 35: G00006 drug_006 moa_A 72 CL00014 cellline_EA tissue_x
#> 36: G00007 drug_007 moa_A 72 CL00014 cellline_EA tissue_x
#> 37: G00008 drug_008 moa_A 72 CL00014 cellline_EA tissue_x
#> 38: G00009 drug_009 moa_A 72 CL00014 cellline_EA tissue_x
#> 39: G00010 drug_010 moa_A 72 CL00014 cellline_EA tissue_x
#> 40: G00011 drug_011 moa_B 72 CL00014 cellline_EA tissue_x
#> 41: G00002 drug_002 moa_A 72 CL00015 cellline_FA tissue_x
#> 42: G00003 drug_003 moa_A 72 CL00015 cellline_FA tissue_x
#> 43: G00004 drug_004 moa_A 72 CL00015 cellline_FA tissue_x
#> 44: G00005 drug_005 moa_A 72 CL00015 cellline_FA tissue_x
#> 45: G00006 drug_006 moa_A 72 CL00015 cellline_FA tissue_x
#> 46: G00007 drug_007 moa_A 72 CL00015 cellline_FA tissue_x
#> 47: G00008 drug_008 moa_A 72 CL00015 cellline_FA tissue_x
#> 48: G00009 drug_009 moa_A 72 CL00015 cellline_FA tissue_x
#> 49: G00010 drug_010 moa_A 72 CL00015 cellline_FA tissue_x
#> 50: G00011 drug_011 moa_B 72 CL00015 cellline_FA tissue_x
#> 51: G00002 drug_002 moa_A 72 CL00016 cellline_GB tissue_y
#> 52: G00003 drug_003 moa_A 72 CL00016 cellline_GB tissue_y
#> 53: G00004 drug_004 moa_A 72 CL00016 cellline_GB tissue_y
#> 54: G00005 drug_005 moa_A 72 CL00016 cellline_GB tissue_y
#> 55: G00006 drug_006 moa_A 72 CL00016 cellline_GB tissue_y
#> 56: G00007 drug_007 moa_A 72 CL00016 cellline_GB tissue_y
#> 57: G00008 drug_008 moa_A 72 CL00016 cellline_GB tissue_y
#> 58: G00009 drug_009 moa_A 72 CL00016 cellline_GB tissue_y
#> 59: G00010 drug_010 moa_A 72 CL00016 cellline_GB tissue_y
#> 60: G00011 drug_011 moa_B 72 CL00016 cellline_GB tissue_y
#> 61: G00002 drug_002 moa_A 72 CL00017 cellline_HB tissue_y
#> 62: G00003 drug_003 moa_A 72 CL00017 cellline_HB tissue_y
#> 63: G00004 drug_004 moa_A 72 CL00017 cellline_HB tissue_y
#> 64: G00005 drug_005 moa_A 72 CL00017 cellline_HB tissue_y
#> 65: G00006 drug_006 moa_A 72 CL00017 cellline_HB tissue_y
#> 66: G00007 drug_007 moa_A 72 CL00017 cellline_HB tissue_y
#> 67: G00008 drug_008 moa_A 72 CL00017 cellline_HB tissue_y
#> 68: G00009 drug_009 moa_A 72 CL00017 cellline_HB tissue_y
#> 69: G00010 drug_010 moa_A 72 CL00017 cellline_HB tissue_y
#> 70: G00011 drug_011 moa_B 72 CL00017 cellline_HB tissue_y
#> 71: G00002 drug_002 moa_A 72 CL00018 cellline_IB tissue_y
#> 72: G00003 drug_003 moa_A 72 CL00018 cellline_IB tissue_y
#> 73: G00004 drug_004 moa_A 72 CL00018 cellline_IB tissue_y
#> 74: G00005 drug_005 moa_A 72 CL00018 cellline_IB tissue_y
#> 75: G00006 drug_006 moa_A 72 CL00018 cellline_IB tissue_y
#> 76: G00007 drug_007 moa_A 72 CL00018 cellline_IB tissue_y
#> 77: G00008 drug_008 moa_A 72 CL00018 cellline_IB tissue_y
#> 78: G00009 drug_009 moa_A 72 CL00018 cellline_IB tissue_y
#> 79: G00010 drug_010 moa_A 72 CL00018 cellline_IB tissue_y
#> 80: G00011 drug_011 moa_B 72 CL00018 cellline_IB tissue_y
#> 81: G00002 drug_002 moa_A 72 CL00019 cellline_JB tissue_z
#> 82: G00003 drug_003 moa_A 72 CL00019 cellline_JB tissue_z
#> 83: G00004 drug_004 moa_A 72 CL00019 cellline_JB tissue_z
#> 84: G00005 drug_005 moa_A 72 CL00019 cellline_JB tissue_z
#> 85: G00006 drug_006 moa_A 72 CL00019 cellline_JB tissue_z
#> 86: G00007 drug_007 moa_A 72 CL00019 cellline_JB tissue_z
#> 87: G00008 drug_008 moa_A 72 CL00019 cellline_JB tissue_z
#> 88: G00009 drug_009 moa_A 72 CL00019 cellline_JB tissue_z
#> 89: G00010 drug_010 moa_A 72 CL00019 cellline_JB tissue_z
#> 90: G00011 drug_011 moa_B 72 CL00019 cellline_JB tissue_z
#> 91: G00002 drug_002 moa_A 72 CL00020 cellline_KB tissue_z
#> 92: G00003 drug_003 moa_A 72 CL00020 cellline_KB tissue_z
#> 93: G00004 drug_004 moa_A 72 CL00020 cellline_KB tissue_z
#> 94: G00005 drug_005 moa_A 72 CL00020 cellline_KB tissue_z
#> 95: G00006 drug_006 moa_A 72 CL00020 cellline_KB tissue_z
#> 96: G00007 drug_007 moa_A 72 CL00020 cellline_KB tissue_z
#> 97: G00008 drug_008 moa_A 72 CL00020 cellline_KB tissue_z
#> 98: G00009 drug_009 moa_A 72 CL00020 cellline_KB tissue_z
#> 99: G00010 drug_010 moa_A 72 CL00020 cellline_KB tissue_z
#> 100: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> Gnumber Drug Name Drug MOA Duration Clid Cell Line Name Tissue
#> Reference Division Time RV Mean RV AOC RV AOC within set range
#> <num> <num> <num> <num>
#> 1: 26 0.4466890 0.55331098 0.62771204
#> 2: 26 0.3939872 0.60601279 0.69549935
#> 3: 26 0.7989283 0.20107172 0.23854321
#> 4: 26 0.7292519 0.27074809 0.30829556
#> 5: 26 0.5948205 0.40517951 0.47306641
#> 6: 26 0.9153135 0.08468651 0.09862965
#> 7: 26 0.6627378 0.33726218 0.37222482
#> 8: 26 0.6541186 0.34588137 0.40814181
#> 9: 26 0.8247285 0.17527151 0.20515620
#> 10: 26 0.3682302 0.63176984 0.74702096
#> 11: 30 0.6926178 0.30738217 0.35949454
#> 12: 30 0.3979780 0.60202205 0.68371983
#> 13: 30 0.9100259 0.08997415 0.10791352
#> 14: 30 0.7873037 0.21269633 0.24486763
#> 15: 30 0.8494189 0.15058108 0.17760851
#> 16: 30 0.8169558 0.18304416 0.20901519
#> 17: 30 0.7755540 0.22444601 0.26336442
#> 18: 30 0.5212853 0.47871472 0.56881144
#> 19: 30 0.7463491 0.25365094 0.30161904
#> 20: 30 0.7616189 0.23838111 0.28326524
#> 21: 34 0.7992747 0.20072525 0.23709408
#> 22: 34 0.4668574 0.53314262 0.61173591
#> 23: 34 0.7261649 0.27383514 0.32331797
#> 24: 34 0.7151504 0.28484957 0.33700199
#> 25: 34 0.6956589 0.30434108 0.36205275
#> 26: 34 0.6779461 0.32205391 0.38244556
#> 27: 34 0.9838111 0.01618889 0.01618889
#> 28: 34 0.5806643 0.41933574 0.49233133
#> 29: 34 0.8776200 0.12238003 0.14379727
#> 30: 34 0.6609849 0.33901514 0.39942016
#> 31: 38 0.8710149 0.12898507 0.15337431
#> 32: 38 0.9173053 0.08269470 0.09639032
#> 33: 38 0.8778150 0.12218503 0.14245939
#> 34: 38 0.9437698 0.05623016 0.06647635
#> 35: 38 0.7144618 0.28553821 0.33774750
#> 36: 38 0.8874428 0.11255721 0.13302031
#> 37: 38 0.9883815 0.01161852 0.01161852
#> 38: 38 0.7852841 0.21471593 0.25298214
#> 39: 38 0.8700763 0.12992370 0.15434173
#> 40: 38 0.5865688 0.41343121 0.47176921
#> 41: 42 0.4828015 0.51719847 0.60667873
#> 42: 42 0.6425053 0.35749468 0.41943708
#> 43: 42 0.3805017 0.61949830 0.71885082
#> 44: 42 0.2977827 0.70221726 0.76597220
#> 45: 42 0.8375294 0.16247062 0.19070324
#> 46: 42 0.5962853 0.40371474 0.47449665
#> 47: 42 0.4657079 0.53429209 0.61134861
#> 48: 42 0.7549529 0.24504707 0.28487547
#> 49: 42 0.8372120 0.16278796 0.18968302
#> 50: 42 0.2524798 0.74752018 0.88177300
#> 51: 46 0.1021560 0.89784398 0.97368081
#> 52: 46 0.3319590 0.66804098 0.79488065
#> 53: 46 0.2102313 0.78976874 0.90450614
#> 54: 46 0.2100452 0.78995479 0.88824111
#> 55: 46 0.3146779 0.68532206 0.81208812
#> 56: 46 0.2311182 0.76888180 0.84899908
#> 57: 46 0.2364875 0.76351250 0.88498708
#> 58: 46 0.3235937 0.67640628 0.79810483
#> 59: 46 0.4821997 0.51780026 0.60821155
#> 60: 46 0.6425491 0.35745090 0.42057145
#> 61: 50 0.4403251 0.55967489 0.66129430
#> 62: 50 0.3158261 0.68417394 0.79476913
#> 63: 50 0.3117162 0.68828381 0.81859408
#> 64: 50 0.4144975 0.58550254 0.68838500
#> 65: 50 0.5330401 0.46695992 0.55422115
#> 66: 50 0.2753604 0.72463961 0.84954049
#> 67: 50 0.2988946 0.70110537 0.81877562
#> 68: 50 0.4775211 0.52247889 0.60461228
#> 69: 50 0.4307934 0.56920661 0.65813446
#> 70: 50 0.5740133 0.42598675 0.50486302
#> 71: 54 0.1817987 0.81820132 0.91385902
#> 72: 54 0.4557736 0.54422640 0.64062126
#> 73: 54 0.3473656 0.65263436 0.75662897
#> 74: 54 0.3722520 0.62774797 0.74215883
#> 75: 54 0.3820939 0.61790607 0.72975315
#> 76: 54 0.4088002 0.59119981 0.67444555
#> 77: 54 0.3086007 0.69139927 0.81546273
#> 78: 54 0.4906996 0.50930040 0.59207687
#> 79: 54 0.4496388 0.55036124 0.63963532
#> 80: 54 0.5613320 0.43866803 0.51481053
#> 81: 58 0.7645125 0.23548748 0.27674936
#> 82: 58 0.7799746 0.22002537 0.25385986
#> 83: 58 0.7029485 0.29705152 0.32948401
#> 84: 58 0.7566058 0.24339421 0.26629466
#> 85: 58 0.8388170 0.16118297 0.18043264
#> 86: 58 0.7862239 0.21377605 0.24324624
#> 87: 58 0.8640795 0.13592048 0.15119347
#> 88: 58 0.7614460 0.23855403 0.26963522
#> 89: 58 0.8471580 0.15284198 0.16513000
#> 90: 58 0.6842658 0.31573420 0.35272441
#> 91: 62 0.6737095 0.32629051 0.38341599
#> 92: 62 0.5683750 0.43162499 0.49907540
#> 93: 62 0.3916886 0.60831136 0.71651338
#> 94: 62 0.4519141 0.54808592 0.64651950
#> 95: 62 0.5938560 0.40614404 0.46394440
#> 96: 62 0.5525910 0.44740898 0.52483930
#> 97: 62 0.3356482 0.66435184 0.78615325
#> 98: 62 0.5045079 0.49549211 0.57777110
#> 99: 62 0.5769999 0.42300010 0.47231044
#> 100: 62 0.4117805 0.58821946 0.69005808
#> Reference Division Time RV Mean RV AOC RV AOC within set range
#> IC50 E Max EC50 E Inf E0 h RV RV R2
#> <num> <num> <num> <num> <num> <num> <num>
#> 1: 0.007253171 0.32793333 0.003795893 0.34682665 1.0000000 1.827031 0.9924695
#> 2: 0.005655581 0.27413333 0.003962986 0.28319787 1.0000000 2.349599 0.9958511
#> 3: Inf 0.70636667 0.016546380 0.71001484 1.0000000 3.159939 0.9918874
#> 4: Inf 0.67963333 0.003304929 0.68717703 1.0000000 2.869796 0.9788260
#> 5: Inf 0.50873333 0.004129702 0.51907021 1.0000000 3.829228 0.9978624
#> 6: Inf 0.86246667 0.023423073 0.87074092 1.0000000 1.396984 0.9622053
#> 7: Inf 0.59466667 0.002397623 0.62344087 1.0000000 2.285910 0.9796018
#> 8: Inf 0.56796667 0.008060179 0.55098117 1.0000000 2.239456 0.9917851
#> 9: Inf 0.72036667 0.031276165 0.71953596 1.0000000 2.336379 0.9894868
#> 10: 0.019384886 0.07090000 0.018136158 0.07568110 1.0000000 2.464822 0.9985658
#> 11: Inf 0.63853333 0.004774753 0.62816339 1.0000000 2.919115 0.9767620
#> 12: 0.003821711 0.27726667 0.003008201 0.31309370 1.0000000 4.111036 0.9952426
#> 13: Inf 0.87040000 0.008254080 0.88286917 1.0000000 5.000000 0.8541039
#> 14: Inf 0.77096667 0.003354506 0.75408088 1.0000000 5.000000 0.9832682
#> 15: Inf 0.80546667 0.007866347 0.80517426 1.0000000 2.241526 0.9725466
#> 16: Inf 0.76806667 0.003815689 0.78433529 1.0000000 2.178830 0.9569420
#> 17: Inf 0.64960000 0.025909149 0.65208728 1.0000000 2.036162 0.9968137
#> 18: 0.015334114 0.35873333 0.009338353 0.36576263 1.0000000 2.651473 0.9984890
#> 19: Inf 0.65570000 0.010664967 0.65748115 1.0000000 2.703715 0.9917990
#> 20: Inf 0.68473333 0.008285395 0.68946503 1.0000000 2.768447 0.9901512
#> 21: Inf 0.69726667 0.018014759 0.70662235 1.0000000 2.255304 0.9949255
#> 22: 0.005175017 0.36916667 0.003431788 0.38161495 1.0000000 3.507307 0.9962628
#> 23: Inf 0.60056667 0.017991972 0.59983667 1.0000000 2.193421 0.9909905
#> 24: Inf 0.59763333 0.014539308 0.59720052 1.0000000 2.214172 0.9973294
#> 25: Inf 0.59926667 0.007397397 0.60975201 1.0000000 3.069376 0.9934571
#> 26: Inf 0.55096667 0.011148175 0.56228258 1.0000000 2.535963 0.9960204
#> 27: Inf 0.97033333 0.000000000 0.98381111 0.9838111 0.000100 0.0000000
#> 28: 0.044349772 0.35713333 0.019771994 0.37777983 1.0000000 1.743888 0.9951205
#> 29: Inf 0.82200000 0.023835769 0.81289660 1.0000000 2.039182 0.9729143
#> 30: Inf 0.55890000 0.007078033 0.56771316 1.0000000 2.322658 0.9935786
#> 31: Inf 0.82480000 0.007404640 0.83458186 1.0000000 3.013686 0.9253169
#> 32: Inf 0.84193333 0.038642612 0.86268158 1.0000000 5.000000 0.9442965
#> 33: Inf 0.78713333 0.038237333 0.79748718 1.0000000 5.000000 0.9908466
#> 34: Inf 0.91773333 0.020858876 0.91588511 1.0000000 5.000000 0.8671881
#> 35: Inf 0.64843333 0.005482997 0.64836791 1.0000000 3.372144 0.9971479
#> 36: Inf 0.80563333 0.020762148 0.83175068 1.0000000 3.262119 0.9613882
#> 37: Inf 0.97366667 0.000000000 0.98838148 0.9883815 0.000100 0.0000000
#> 38: Inf 0.66726667 0.024503188 0.67026768 1.0000000 5.000000 0.9917875
#> 39: Inf 0.83416667 0.008516796 0.83009341 1.0000000 2.706836 0.9367858
#> 40: 0.103693590 0.22530000 0.077874576 0.21531639 1.0000000 1.966991 0.9976196
#> 41: 0.010722078 0.33776667 0.006294304 0.35077573 1.0000000 2.270037 0.9991870
#> 42: Inf 0.55923333 0.005301487 0.56156486 1.0000000 2.740291 0.9951004
#> 43: 0.006229871 0.23093333 0.004661971 0.25237654 1.0000000 2.423790 0.9933838
#> 44: 0.002756447 0.20110000 0.002085738 0.22629021 1.0000000 2.161036 0.9941359
#> 45: Inf 0.77860000 0.007310403 0.79181981 1.0000000 2.065713 0.9820954
#> 46: 0.041965155 0.41790000 0.012099942 0.44418366 1.0000000 1.763005 0.9967096
#> 47: 0.005912214 0.36410000 0.003552790 0.37709397 1.0000000 2.755200 0.9964623
#> 48: Inf 0.70263333 0.004561251 0.70521133 1.0000000 2.642410 0.9930514
#> 49: Inf 0.76936667 0.012481407 0.77448135 1.0000000 1.432588 0.9629959
#> 50: 0.007884476 0.02790000 0.007623490 0.03706278 1.0000000 2.287981 0.9995991
#> 51: 0.001975139 0.01156667 0.001941693 0.02047816 1.0000000 2.448673 0.9992976
#> 52: 0.013697468 0.06936667 0.013030558 0.07094849 1.0000000 3.065907 0.9982225
#> 53: 0.003811979 0.06773333 0.003585337 0.07825779 1.0000000 2.776919 0.9969366
#> 54: 0.003197359 0.08630000 0.002932087 0.09935284 1.0000000 2.557727 0.9990998
#> 55: 0.014902515 0.01756667 0.014508564 0.03128655 1.0000000 2.411884 0.9989330
#> 56: 0.002887489 0.13533333 0.002461805 0.13678567 1.0000000 2.003949 0.9940489
#> 57: 0.005396956 0.06396667 0.005034691 0.06871316 1.0000000 2.127642 0.9977338
#> 58: 0.015444308 0.04450000 0.014793650 0.04081369 1.0000000 1.978326 0.9993449
#> 59: 0.032638339 0.17626667 0.027413659 0.18981432 1.0000000 2.736872 0.9994655
#> 60: Inf 0.57070000 0.005350482 0.56115445 1.0000000 2.940905 0.9878645
#> 61: 0.023097263 0.17430000 0.019657332 0.17067228 1.0000000 2.589266 0.9980176
#> 62: 0.004922621 0.16046667 0.004218802 0.18540041 1.0000000 3.002839 0.9978019
#> 63: 0.010326282 0.07083333 0.009658844 0.08373933 1.0000000 2.743208 0.9966324
#> 64: 0.027637201 0.11686667 0.025274379 0.09621464 1.0000000 2.391418 0.9979799
#> 65: 0.019427772 0.34556667 0.011549019 0.36203554 1.0000000 2.475686 0.9965915
#> 66: 0.009224850 0.05420000 0.008730319 0.04790721 1.0000000 1.827993 0.9990550
#> 67: 0.007990484 0.08710000 0.007043304 0.10560283 1.0000000 1.880336 0.9988034
#> 68: 0.054323446 0.07786667 0.049549089 0.09209706 1.0000000 2.213005 0.9983842
#> 69: 0.008297512 0.29680000 0.005151240 0.30315714 1.0000000 1.955457 0.9958787
#> 70: 0.028380166 0.37660000 0.016287291 0.38712847 1.0000000 2.680251 0.9975327
#> 71: 0.003121891 0.06380000 0.002908151 0.06403699 1.0000000 1.932432 0.9991981
#> 72: 0.015278400 0.26503333 0.010185821 0.26943207 1.0000000 1.909176 0.9995183
#> 73: 0.007000949 0.19893333 0.005440592 0.19547452 1.0000000 1.966440 0.9994474
#> 74: 0.010133991 0.19443333 0.008351180 0.18112340 1.0000000 2.324659 0.9966253
#> 75: 0.022055538 0.08350000 0.020776435 0.07624990 1.0000000 2.769539 0.9992905
#> 76: 0.007029613 0.29376667 0.004287339 0.29150899 1.0000000 1.769006 0.9973898
#> 77: 0.013769074 0.02206667 0.013254560 0.03556904 1.0000000 1.937726 0.9990756
#> 78: 0.047179141 0.14253333 0.037914493 0.15699796 1.0000000 1.723879 0.9986513
#> 79: 0.045215408 0.05843333 0.043031281 0.06820615 1.0000000 2.962191 0.9993880
#> 80: 0.042486343 0.29903333 0.025152816 0.32334398 1.0000000 1.984697 0.9960406
#> 81: Inf 0.65316667 0.019245011 0.65209837 1.0000000 1.796886 0.9981400
#> 82: Inf 0.59670000 0.055689068 0.60914083 1.0000000 2.665200 0.9969579
#> 83: 0.295080096 0.30650000 0.158198620 0.34093110 1.0000000 1.837149 0.9963409
#> 84: 0.413743153 0.41173333 0.206332658 0.42342449 1.0000000 2.696824 0.9985293
#> 85: Inf 0.65686667 0.129212028 0.65883941 1.0000000 2.006733 0.9949262
#> 86: Inf 0.56523333 0.085602158 0.58627595 1.0000000 3.117706 0.9948828
#> 87: Inf 0.68853333 0.149067206 0.70263542 1.0000000 3.578535 0.9913418
#> 88: Inf 0.52300000 0.102208367 0.52064083 1.0000000 2.321359 0.9918926
#> 89: Inf 0.61000000 0.256158972 0.61685311 1.0000000 2.023378 0.9948254
#> 90: 0.236075692 0.30246667 0.135223132 0.32473738 1.0000000 1.881323 0.9969943
#> 91: Inf 0.52713333 0.013128583 0.54530841 1.0000000 1.733740 0.9968381
#> 92: 0.070162438 0.22003333 0.050619652 0.24695917 1.0000000 2.086104 0.9970699
#> 93: 0.010695136 0.21133333 0.008294007 0.20699055 1.0000000 2.101833 0.9960998
#> 94: 0.025509994 0.18053333 0.021456873 0.17635164 1.0000000 2.513797 0.9988743
#> 95: 0.102279380 0.20620000 0.075806992 0.23335970 1.0000000 2.099067 0.9968471
#> 96: 0.039032319 0.28623333 0.029513143 0.29115866 1.0000000 3.122947 0.9976141
#> 97: 0.012891906 0.08013333 0.011778656 0.08958619 1.0000000 2.186258 0.9990599
#> 98: 0.045034344 0.20156667 0.035484367 0.18949638 1.0000000 1.998935 0.9961207
#> 99: 0.150209032 0.07513333 0.137152296 0.09235428 1.0000000 2.245643 0.9988156
#> 100: 0.027440547 0.08603333 0.024485958 0.09662172 1.0000000 1.884916 0.9986615
#> IC50 E Max EC50 E Inf E0 h RV RV R2
#> RV p Value RV Rss RV Sd Avg Fit Type RV
#> <num> <num> <num> <char>
#> 1: 3.705769e-08 0.0027788222 0.02424423 DRC3pHillFitModelFixS0
#> 2: 4.600131e-09 0.0021823404 0.02195104 DRC3pHillFitModelFixS0
#> 3: 4.809026e-08 0.0011623407 0.02315049 DRC3pHillFitModelFixS0
#> 4: 1.381366e-06 0.0018580999 0.02433754 DRC3pHillFitModelFixS0
#> 5: 4.515583e-10 0.0006002563 0.02914251 DRC3pHillFitModelFixS0
#> 6: 1.049565e-05 0.0010089336 0.03095134 DRC3pHillFitModelFixS0
#> 7: 1.212200e-06 0.0021497125 0.02851709 DRC3pHillFitModelFixS0
#> 8: 5.024614e-08 0.0022433269 0.02120201 DRC3pHillFitModelFixS0
#> 9: 1.191422e-07 0.0014484927 0.02368805 DRC3pHillFitModelFixS0
#> 10: 1.117095e-10 0.0020514821 0.02467602 DRC3pHillFitModelFixS0
#> 11: 1.912923e-06 0.0042266456 0.02026923 DRC3pHillFitModelFixS0
#> 12: 7.426431e-09 0.0021879035 0.02564250 DRC3pHillFitModelFixS0
#> 13: 1.186186e-03 0.0023608040 0.03624754 DRC3pHillFitModelFixS0
#> 14: 6.059013e-07 0.0010166387 0.02462014 DRC3pHillFitModelFixS0
#> 15: 3.428366e-06 0.0013962272 0.02581034 DRC3pHillFitModelFixS0
#> 16: 1.656493e-05 0.0022229434 0.02491576 DRC3pHillFitModelFixS0
#> 17: 1.825950e-09 0.0006398224 0.03482572 DRC3pHillFitModelFixS0
#> 18: 1.340914e-10 0.0008475955 0.02606777 DRC3pHillFitModelFixS0
#> 19: 4.995008e-08 0.0014512290 0.02352835 DRC3pHillFitModelFixS0
#> 20: 9.480595e-08 0.0014125688 0.02706624 DRC3pHillFitModelFixS0
#> 21: 9.308666e-09 0.0007114611 0.02403599 DRC3pHillFitModelFixS0
#> 22: 3.190785e-09 0.0015119310 0.02698012 DRC3pHillFitModelFixS0
#> 23: 6.941415e-08 0.0023665643 0.02577172 DRC3pHillFitModelFixS0
#> 24: 9.843622e-10 0.0006363358 0.02525688 DRC3pHillFitModelFixS0
#> 25: 2.265652e-08 0.0013783062 0.02269828 DRC3pHillFitModelFixS0
#> 26: 3.976072e-09 0.0011374563 0.02402262 DRC3pHillFitModelFixS0
#> 27: 4.979239e-01 0.0029436207 0.02620160 DRCConstantFitResult
#> 28: 8.115446e-09 0.0027937482 0.02903764 DRC3pHillFitModelFixS0
#> 29: 3.270314e-06 0.0015619403 0.02427360 DRC3pHillFitModelFixS0
#> 30: 2.121800e-08 0.0015913349 0.02469797 DRC3pHillFitModelFixS0
#> 31: 1.138357e-04 0.0040117584 0.02546309 DRC3pHillFitModelFixS0
#> 32: 4.079327e-05 0.0022454435 0.03159417 DRC3pHillFitModelFixS0
#> 33: 7.337283e-08 0.0007607914 0.02897195 DRC3pHillFitModelFixS0
#> 34: 8.537470e-04 0.0032197577 0.02385616 DRC3pHillFitModelFixS0
#> 35: 1.238942e-09 0.0004630470 0.02145847 DRC3pHillFitModelFixS0
#> 36: 1.131147e-05 0.0018341727 0.02696312 DRC3pHillFitModelFixS0
#> 37: 3.003192e-01 0.0034434491 0.02670075 DRCConstantFitResult
#> 38: 5.019502e-08 0.0015741830 0.02216258 DRC3pHillFitModelFixS0
#> 39: 6.351119e-05 0.0023356139 0.02237141 DRC3pHillFitModelFixS0
#> 40: 6.580954e-10 0.0026451685 0.03512306 DRC3pHillFitModelFixS0
#> 41: 1.532058e-11 0.0004309408 0.02583750 DRC3pHillFitModelFixS0
#> 42: 8.232852e-09 0.0011916253 0.02329129 DRC3pHillFitModelFixS0
#> 43: 2.355796e-08 0.0039254874 0.02481987 DRC3pHillFitModelFixS0
#> 44: 1.544166e-08 0.0022236840 0.02302050 DRC3pHillFitModelFixS0
#> 45: 7.680224e-07 0.0010163372 0.02911082 DRC3pHillFitModelFixS0
#> 46: 2.043397e-09 0.0014121632 0.02750852 DRC3pHillFitModelFixS0
#> 47: 2.633342e-09 0.0013740389 0.01788683 DRC3pHillFitModelFixS0
#> 48: 2.796599e-08 0.0007360079 0.03663836 DRC3pHillFitModelFixS0
#> 49: 9.747072e-06 0.0024229473 0.01589380 DRC3pHillFitModelFixS0
#> 50: 1.290124e-12 0.0004814205 0.02605429 DRC3pHillFitModelFixS0
#> 51: 9.185549e-12 0.0004198723 0.01347179 DRC3pHillFitModelFixS0
#> 52: 2.367642e-10 0.0023752601 0.02166174 DRC3pHillFitModelFixS0
#> 53: 1.591078e-09 0.0027166839 0.02379256 DRC3pHillFitModelFixS0
#> 54: 2.188336e-11 0.0006322521 0.02440520 DRC3pHillFitModelFixS0
#> 55: 3.968447e-11 0.0015443091 0.02854761 DRC3pHillFitModelFixS0
#> 56: 1.625854e-08 0.0030714525 0.02768624 DRC3pHillFitModelFixS0
#> 57: 5.540498e-10 0.0021463145 0.02021322 DRC3pHillFitModelFixS0
#> 58: 7.196834e-12 0.0008883295 0.02920943 DRC3pHillFitModelFixS0
#> 59: 3.530406e-12 0.0006289186 0.02246907 DRC3pHillFitModelFixS0
#> 60: 1.968793e-07 0.0028158117 0.02061972 DRC3pHillFitModelFixS0
#> 61: 3.468423e-10 0.0024284335 0.02328919 DRC3pHillFitModelFixS0
#> 62: 4.979588e-10 0.0016845191 0.02727108 DRC3pHillFitModelFixS0
#> 63: 2.216266e-09 0.0042541545 0.02529924 DRC3pHillFitModelFixS0
#> 64: 3.705174e-10 0.0027829406 0.02494556 DRC3pHillFitModelFixS0
#> 65: 2.311928e-09 0.0021365407 0.02789728 DRC3pHillFitModelFixS0
#> 66: 2.594026e-11 0.0010823145 0.03555896 DRC3pHillFitModelFixS0
#> 67: 5.926379e-11 0.0011411900 0.02594352 DRC3pHillFitModelFixS0
#> 68: 1.695655e-10 0.0024649969 0.02468871 DRC3pHillFitModelFixS0
#> 69: 4.494010e-09 0.0021801892 0.02364677 DRC3pHillFitModelFixS0
#> 70: 7.461140e-10 0.0015856291 0.02115656 DRC3pHillFitModelFixS0
#> 71: 1.460497e-11 0.0005404075 0.02845357 DRC3pHillFitModelFixS0
#> 72: 2.452621e-12 0.0003467009 0.02094491 DRC3pHillFitModelFixS0
#> 73: 3.967682e-12 0.0004025462 0.03261254 DRC3pHillFitModelFixS0
#> 74: 2.232695e-09 0.0029765716 0.01687243 DRC3pHillFitModelFixS0
#> 75: 9.514306e-12 0.0010395275 0.02890447 DRC3pHillFitModelFixS0
#> 76: 9.085852e-10 0.0012150473 0.02575115 DRC3pHillFitModelFixS0
#> 77: 2.401496e-11 0.0012638360 0.02401299 DRC3pHillFitModelFixS0
#> 78: 9.008741e-11 0.0015699934 0.03358047 DRC3pHillFitModelFixS0
#> 79: 5.670183e-12 0.0010056258 0.02405125 DRC3pHillFitModelFixS0
#> 80: 3.905880e-09 0.0029102882 0.03048010 DRC3pHillFitModelFixS0
#> 81: 2.775246e-10 0.0003485312 0.02875185 DRC3pHillFitModelFixS0
#> 82: 1.552798e-09 0.0009178606 0.02807435 DRC3pHillFitModelFixS0
#> 83: 2.963407e-09 0.0027780381 0.02321208 DRC3pHillFitModelFixS0
#> 84: 1.219970e-10 0.0009193400 0.03321846 DRC3pHillFitModelFixS0
#> 85: 9.303663e-09 0.0010726159 0.02970061 DRC3pHillFitModelFixS0
#> 86: 9.585348e-09 0.0017207801 0.02613007 DRC3pHillFitModelFixS0
#> 87: 6.039404e-08 0.0016026034 0.03144202 DRC3pHillFitModelFixS0
#> 88: 4.798189e-08 0.0037064480 0.02837621 DRC3pHillFitModelFixS0
#> 89: 9.967103e-09 0.0013976276 0.03160124 DRC3pHillFitModelFixS0
#> 90: 1.488693e-09 0.0025492991 0.01994518 DRC3pHillFitModelFixS0
#> 91: 1.777626e-09 0.0009436559 0.02358830 DRC3pHillFitModelFixS0
#> 92: 1.361674e-09 0.0029342522 0.02633392 DRC3pHillFitModelFixS0
#> 93: 3.705262e-09 0.0032832350 0.02144606 DRC3pHillFitModelFixS0
#> 94: 4.786781e-11 0.0013274649 0.03026998 DRC3pHillFitModelFixS0
#> 95: 1.759891e-09 0.0035472702 0.02618347 DRC3pHillFitModelFixS0
#> 96: 6.634336e-10 0.0023287486 0.01817215 DRC3pHillFitModelFixS0
#> 97: 2.547129e-11 0.0011386370 0.02235921 DRC3pHillFitModelFixS0
#> 98: 3.636093e-09 0.0042739653 0.02298094 DRC3pHillFitModelFixS0
#> 99: 5.718652e-11 0.0018424204 0.03151223 DRC3pHillFitModelFixS0
#> 100: 8.773134e-11 0.0018446214 0.03335063 DRC3pHillFitModelFixS0
#> RV p Value RV Rss RV Sd Avg Fit Type RV
convert_se_assay_to_custom_dt(se, "Metrics", output_table = "Metrics_initial")
#> rId cId x_mean
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.4466890
#> 2: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.4729298
#> 3: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.3939872
#> 4: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.3932199
#> 5: G00004_drug_004_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.7989283
#> ---
#> 196: G00009_drug_009_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.0774842
#> 197: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.5769999
#> 198: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.1991504
#> 199: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 0.4117805
#> 200: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 -0.1148134
#> x_AOC x_AOC_range xc50 x_max ec50 x_inf
#> <num> <num> <num> <num> <num> <num>
#> 1: 0.5533110 0.6277120 0.007253171 0.32793333 0.003795893 0.34682665
#> 2: 0.5270702 0.6048472 0.008956223 0.33660000 0.004512560 0.36516781
#> 3: 0.6060128 0.6954994 0.005655581 0.27413333 0.003962986 0.28319787
#> 4: 0.6067801 0.7027714 0.006591468 0.25136667 0.004714084 0.26639679
#> 5: 0.2010717 0.2385432 Inf 0.70636667 0.016546380 0.71001484
#> ---
#> 196: 0.9225158 1.0742560 0.026077313 -0.49686667 0.037516853 -0.52393526
#> 197: 0.4230001 0.4723104 0.150209032 0.07513333 0.137152296 0.09235428
#> 198: 0.8008496 0.8915995 0.096729600 -0.78626667 0.146270629 -0.74430401
#> 199: 0.5882195 0.6900581 0.027440547 0.08603333 0.024485958 0.09662172
#> 200: 1.1148134 1.3059605 0.016239553 -0.76026667 0.026434030 -0.73401896
#> x_0 h r2 p_value rss x_sd_avg
#> <num> <num> <num> <num> <num> <num>
#> 1: 1 1.827031 0.9924695 3.705769e-08 0.002778822 0.02424423
#> 2: 1 1.911901 0.9884406 1.660656e-07 0.004530345 0.03203268
#> 3: 1 2.349599 0.9958511 4.600131e-09 0.002182340 0.02195104
#> 4: 1 2.270093 0.9905292 8.267143e-08 0.005670066 0.03075240
#> 5: 1 3.159939 0.9918874 4.809026e-08 0.001162341 0.02315049
#> ---
#> 196: 1 1.970723 0.9955609 5.828304e-09 0.017400921 0.04602459
#> 197: 1 2.245643 0.9988156 5.718652e-11 0.001842420 0.03151223
#> 198: 1 2.204685 0.9985705 1.104466e-10 0.008161064 0.06333498
#> 199: 1 1.884916 0.9986615 8.773134e-11 0.001844621 0.03335063
#> 200: 1 1.854308 0.9987249 7.403286e-11 0.006484241 0.07007818
#> fit_type maxlog10Concentration N_conc normalization_type
#> <char> <num> <int> <char>
#> 1: DRC3pHillFitModelFixS0 1 9 RV
#> 2: DRC3pHillFitModelFixS0 1 9 GR
#> 3: DRC3pHillFitModelFixS0 1 9 RV
#> 4: DRC3pHillFitModelFixS0 1 9 GR
#> 5: DRC3pHillFitModelFixS0 1 9 RV
#> ---
#> 196: DRC3pHillFitModelFixS0 1 9 GR
#> 197: DRC3pHillFitModelFixS0 1 9 RV
#> 198: DRC3pHillFitModelFixS0 1 9 GR
#> 199: DRC3pHillFitModelFixS0 1 9 RV
#> 200: DRC3pHillFitModelFixS0 1 9 GR
#> fit_source Gnumber DrugName drug_moa Duration clid CellLineName
#> <char> <char> <char> <char> <num> <char> <char>
#> 1: gDR G00002 drug_002 moa_A 72 CL00011 cellline_BA
#> 2: gDR G00002 drug_002 moa_A 72 CL00011 cellline_BA
#> 3: gDR G00003 drug_003 moa_A 72 CL00011 cellline_BA
#> 4: gDR G00003 drug_003 moa_A 72 CL00011 cellline_BA
#> 5: gDR G00004 drug_004 moa_A 72 CL00011 cellline_BA
#> ---
#> 196: gDR G00009 drug_009 moa_A 72 CL00020 cellline_KB
#> 197: gDR G00010 drug_010 moa_A 72 CL00020 cellline_KB
#> 198: gDR G00010 drug_010 moa_A 72 CL00020 cellline_KB
#> 199: gDR G00011 drug_011 moa_B 72 CL00020 cellline_KB
#> 200: gDR G00011 drug_011 moa_B 72 CL00020 cellline_KB
#> Tissue ReferenceDivisionTime
#> <char> <num>
#> 1: tissue_x 26
#> 2: tissue_x 26
#> 3: tissue_x 26
#> 4: tissue_x 26
#> 5: tissue_x 26
#> ---
#> 196: tissue_z 62
#> 197: tissue_z 62
#> 198: tissue_z 62
#> 199: tissue_z 62
#> 200: tissue_z 62
convert_se_assay_to_custom_dt(se, "Averaged")
#> Key: <r Id, c Id, Concentration, Gnumber, Drug Name, Drug MOA, Duration, Clid, Cell Line Name, Tissue, Reference Division Time>
#> r Id c Id Concentration
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.001000000
#> 2: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.003162278
#> 3: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.010000000
#> 4: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.031622777
#> 5: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.100000000
#> ---
#> 896: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 0.100000000
#> 897: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 0.316227766
#> 898: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 1.000000000
#> 899: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 3.162277660
#> 900: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 10.000000000
#> Gnumber Drug Name Drug MOA Duration Clid Cell Line Name Tissue
#> <char> <char> <char> <num> <char> <char> <char>
#> 1: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 2: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 3: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 4: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 5: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> ---
#> 896: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 897: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 898: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 899: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 900: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> Reference Division Time Relative Viability GR value
#> <num> <num> <num>
#> 1: 26 0.92496667 0.9444333
#> 2: 26 0.73910000 0.7931000
#> 3: 26 0.43593333 0.4813333
#> 4: 26 0.33626667 0.3482000
#> 5: 26 0.34670000 0.3634000
#> ---
#> 896: 62 0.15343333 -0.6027000
#> 897: 62 0.10486667 -0.7146000
#> 898: 62 0.11136667 -0.6985000
#> 899: 62 0.08603333 -0.7602667
#> 900: 62 0.09353333 -0.7411000
#> Std Relative Viability Std GR value
#> <num> <num>
#> 1: 0.01066130 0.008058743
#> 2: 0.01484621 0.013021521
#> 3: 0.03071503 0.038118412
#> 4: 0.03491938 0.050414581
#> 5: 0.03191175 0.045352067
#> ---
#> 896: 0.03347721 0.075558785
#> 897: 0.03833593 0.089379024
#> 898: 0.02465651 0.058096385
#> 899: 0.04227556 0.100949212
#> 900: 0.02869866 0.069724529