Convert a SummarizedExperiment assay to a long data.table and conduct some post processing steps
Source:R/convert_mae_se_assay_to_dt.R
convert_se_assay_to_custom_dt.RdConvert an assay within a SummarizedExperiment object to a long data.table. Then condcut some post processing steps.
Arguments
- se
A SummarizedExperiment object holding raw and/or processed dose-response data in its assays.
- assay_name
String of name of the assay to transform within the
se.- output_table
String of type name of the output data.table
Details
Current strategy is per-assay specific.
combo assays: conversion to data.table only (with
wide_structure= FALSE)'Metrics' assay can be converted to three types of outputs:
Metrics_initial (conversion to data.table only, with
wide_structure= FALSE)Metrics_raw: same as Metrics_initial followed by:
fix for 'EC50' and 'Metrics_rownames'
flatten
prettifying and dropping excess variables
Metrics (same as Metrics_raw + capVals)
'Normalization' and 'Averaged' assay:
conversion to data.table (with
wide_structure= TRUE)prettifying and dropping excess variables
NOTE: to extract information about 'Control' data, simply call the
function with the name of the assay holding data on controls.
To extract the reference data in to same format as 'Averaged' use convert_se_ref_assay_to_dt.
Examples
mae <- get_synthetic_data("finalMAE_small")
se <- mae[[1]]
convert_se_assay_to_custom_dt(se, "Metrics")
#> r Id c Id GR Mean
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.472929759
#> 2: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.393219859
#> 3: G00004_drug_004_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.839327136
#> 4: G00005_drug_005_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.781708106
#> 5: G00006_drug_006_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.646759184
#> 6: G00007_drug_007_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.937436799
#> 7: G00008_drug_008_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.720542898
#> 8: G00009_drug_009_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.704849585
#> 9: G00010_drug_010_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.860814168
#> 10: G00011_drug_011_moa_B_72 CL00011_cellline_BA_tissue_x_26 0.207159460
#> 11: G00002_drug_002_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.710189522
#> 12: G00003_drug_003_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.332747901
#> 13: G00004_drug_004_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.922099383
#> 14: G00005_drug_005_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.808309237
#> 15: G00006_drug_006_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.866903473
#> 16: G00007_drug_007_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.836985050
#> 17: G00008_drug_008_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.791435957
#> 18: G00009_drug_009_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.491313620
#> 19: G00010_drug_010_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.763749516
#> 20: G00011_drug_011_moa_B_72 CL00012_cellline_CA_tissue_x_30 0.780650008
#> 21: G00002_drug_002_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.794248968
#> 22: G00003_drug_003_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.374827861
#> 23: G00004_drug_004_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.709167535
#> 24: G00005_drug_005_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.697104582
#> 25: G00006_drug_006_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.676875616
#> 26: G00007_drug_007_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.652414714
#> 27: G00008_drug_008_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.984385185
#> 28: G00009_drug_009_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.514432888
#> 29: G00010_drug_010_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.878482510
#> 30: G00011_drug_011_moa_B_72 CL00013_cellline_DA_tissue_x_34 0.634715550
#> 31: G00002_drug_002_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.858014876
#> 32: G00003_drug_003_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.909591493
#> 33: G00004_drug_004_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.864237280
#> 34: G00005_drug_005_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.939294715
#> 35: G00006_drug_006_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.669107225
#> 36: G00007_drug_007_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.876104175
#> 37: G00008_drug_008_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.987433333
#> 38: G00009_drug_009_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.752739905
#> 39: G00010_drug_010_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.857326327
#> 40: G00011_drug_011_moa_B_72 CL00014_cellline_EA_tissue_x_38 0.435872637
#> 41: G00002_drug_002_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.280017800
#> 42: G00003_drug_003_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.536315316
#> 43: G00004_drug_004_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.097480450
#> 44: G00005_drug_005_moa_A_72 CL00015_cellline_FA_tissue_x_42 -0.038391125
#> 45: G00006_drug_006_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.801673120
#> 46: G00007_drug_007_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.459163515
#> 47: G00008_drug_008_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.261931402
#> 48: G00009_drug_009_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.694250375
#> 49: G00010_drug_010_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.800908530
#> 50: G00011_drug_011_moa_B_72 CL00015_cellline_FA_tissue_x_42 -0.288561464
#> 51: G00002_drug_002_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.645509596
#> 52: G00003_drug_003_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.151209620
#> 53: G00004_drug_004_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.362400138
#> 54: G00005_drug_005_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.328454740
#> 55: G00006_drug_006_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.224809588
#> 56: G00007_drug_007_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.260281000
#> 57: G00008_drug_008_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.314141961
#> 58: G00009_drug_009_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.188230693
#> 59: G00010_drug_010_moa_A_72 CL00016_cellline_GB_tissue_y_46 0.177463519
#> 60: G00011_drug_011_moa_B_72 CL00016_cellline_GB_tissue_y_46 0.499202800
#> 61: G00002_drug_002_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.059329643
#> 62: G00003_drug_003_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.156760855
#> 63: G00004_drug_004_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.218107316
#> 64: G00005_drug_005_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.017982323
#> 65: G00006_drug_006_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.264938349
#> 66: G00007_drug_007_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.305037682
#> 67: G00008_drug_008_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.212954966
#> 68: G00009_drug_009_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.091984103
#> 69: G00010_drug_010_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.089668620
#> 70: G00011_drug_011_moa_B_72 CL00017_cellline_HB_tissue_y_50 0.334329487
#> 71: G00002_drug_002_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.501402843
#> 72: G00003_drug_003_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.077780973
#> 73: G00004_drug_004_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.131760019
#> 74: G00005_drug_005_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.093988826
#> 75: G00006_drug_006_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.125734009
#> 76: G00007_drug_007_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.003190178
#> 77: G00008_drug_008_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.286159124
#> 78: G00009_drug_009_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.112201368
#> 79: G00010_drug_010_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.005980476
#> 80: G00011_drug_011_moa_B_72 CL00018_cellline_IB_tissue_y_54 0.267043249
#> 81: G00002_drug_002_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.606827931
#> 82: G00003_drug_003_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.630511020
#> 83: G00004_drug_004_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.483973989
#> 84: G00005_drug_005_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.581204001
#> 85: G00006_drug_006_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.731518966
#> 86: G00007_drug_007_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.639612759
#> 87: G00008_drug_008_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.774175841
#> 88: G00009_drug_009_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.595786753
#> 89: G00010_drug_010_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.744384655
#> 90: G00011_drug_011_moa_B_72 CL00019_cellline_JB_tissue_z_58 0.449758703
#> 91: G00002_drug_002_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.418086223
#> 92: G00003_drug_003_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.203645096
#> 93: G00004_drug_004_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.132168662
#> 94: G00005_drug_005_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.024941265
#> 95: G00006_drug_006_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.249504542
#> 96: G00007_drug_007_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.176988967
#> 97: G00008_drug_008_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.264481101
#> 98: G00009_drug_009_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.077484203
#> 99: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.199150357
#> 100: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 -0.114813416
#> r Id c Id GR Mean
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> <num> <num> <num> <num> <num>
#> 1: 0.52707024 0.60484720 0.008956223 0.33660000 0.004512560
#> 2: 0.60678014 0.70277140 0.006591468 0.25136667 0.004714084
#> 3: 0.16067286 0.19050089 30.000000000 0.76383333 0.017152797
#> 4: 0.21829189 0.25018175 30.000000000 0.73936667 0.003425139
#> 5: 0.35324082 0.41393595 30.000000000 0.56643333 0.004372707
#> 6: 0.06256320 0.06575521 30.000000000 0.89593333 6.055622159
#> 7: 0.27945710 0.30997686 30.000000000 0.65743333 0.002559558
#> 8: 0.29515042 0.34870740 30.000000000 0.63046667 0.008778928
#> 9: 0.13918583 0.16273320 30.000000000 0.77656667 0.032779888
#> 10: 0.79284054 0.93195933 0.021403060 -0.24116667 0.025129204
#> 11: 0.28981048 0.33967455 30.000000000 0.65893333 0.005025942
#> 12: 0.66725210 0.76169198 0.003994252 0.17163333 0.003302060
#> 13: 0.07790062 0.09343051 30.000000000 0.88726667 0.008287858
#> 14: 0.19169076 0.22105147 30.000000000 0.79443333 0.003408721
#> 15: 0.13309653 0.15708142 30.000000000 0.82726667 0.008098714
#> 16: 0.16301495 0.18647466 30.000000000 0.79136667 0.003969114
#> 17: 0.20856404 0.24449577 30.000000000 0.67090000 0.027533368
#> 18: 0.50868638 0.60551778 0.014718394 0.30453333 0.010370991
#> 19: 0.23625048 0.28073456 30.000000000 0.67690000 0.011214419
#> 20: 0.21934999 0.26078562 30.000000000 0.70800000 0.008628168
#> 21: 0.20575103 0.24291610 30.000000000 0.68636667 0.018792763
#> 22: 0.62517214 0.72107940 0.004733541 0.24863333 0.003733333
#> 23: 0.29083246 0.34315973 30.000000000 0.57196667 0.019154852
#> 24: 0.30289542 0.35827349 30.000000000 0.56803333 0.015397125
#> 25: 0.32312438 0.38472189 30.000000000 0.57023333 0.007742051
#> 26: 0.34758529 0.41267609 30.000000000 0.50863333 0.011835446
#> 27: 0.01561481 0.01561481 30.000000000 0.97146667 0.000000000
#> 28: 0.48556711 0.56936523 0.034901667 0.22980000 0.022820133
#> 29: 0.12151749 0.14271246 30.000000000 0.82306667 0.024473312
#> 30: 0.36528445 0.43067820 30.000000000 0.51870000 0.007550572
#> 31: 0.14198512 0.16878024 30.000000000 0.80660000 0.007501824
#> 32: 0.09040851 0.10536618 30.000000000 0.82636667 0.038864061
#> 33: 0.13576272 0.15824641 30.000000000 0.76243333 0.038650933
#> 34: 0.06070529 0.07176469 30.000000000 0.91113333 0.020890672
#> 35: 0.33089278 0.39183474 30.000000000 0.59120000 0.005647023
#> 36: 0.12389583 0.14638273 30.000000000 0.78433333 0.021030163
#> 37: 0.01256667 0.01256667 30.000000000 0.97186667 0.000000000
#> 38: 0.24726009 0.29120537 30.000000000 0.61536667 0.024975182
#> 39: 0.14267367 0.16980694 30.000000000 0.81726667 0.008782943
#> 40: 0.56412736 0.63987995 0.083979077 -0.09190000 0.092656739
#> 41: 0.71998220 0.84636750 0.007532111 0.06133333 0.006931018
#> 42: 0.46368468 0.54490372 0.011313171 0.42486667 0.005539077
#> 43: 0.90251955 1.05310942 0.004804846 -0.15033333 0.005196465
#> 44: 1.03839112 1.14486626 0.002096183 -0.21590000 0.002402173
#> 45: 0.19832688 0.23289841 30.000000000 0.72833333 0.007472182
#> 46: 0.54083649 0.63547037 0.019685244 0.20183333 0.013344832
#> 47: 0.73806860 0.84884751 0.004278853 0.10913333 0.003823207
#> 48: 0.30574963 0.35592969 30.000000000 0.62720000 0.004699445
#> 49: 0.19909147 0.23175051 30.000000000 0.71623333 0.013054619
#> 50: 1.28856146 1.52231622 0.006501568 -0.76076667 0.009877882
#> 51: 1.64550960 1.81869399 0.001554925 -0.88523333 0.002461726
#> 52: 1.15120962 1.36693104 0.011295294 -0.63760000 0.014964922
#> 53: 1.36240014 1.58088594 0.003102882 -0.64316667 0.003627803
#> 54: 1.32845474 1.52484992 0.002821583 -0.59106667 0.003261246
#> 55: 1.22480959 1.44589294 0.011797654 -0.85010000 0.018211003
#> 56: 1.26028100 1.40891804 0.002124075 -0.44813333 0.002908819
#> 57: 1.31414196 1.53378544 0.004126866 -0.66630000 0.006208157
#> 58: 1.18823069 1.39705508 0.011541663 -0.74830000 0.019093562
#> 59: 0.82253648 0.96378586 0.025291861 -0.34083333 0.030462173
#> 60: 0.50079720 0.59001656 0.009069128 0.39763333 0.005532738
#> 61: 0.94067036 1.10926395 0.017069264 -0.40870000 0.021770780
#> 62: 1.15676086 1.35220803 0.003518715 -0.43993333 0.003926883
#> 63: 1.21810732 1.44505824 0.007845694 -0.68250000 0.011080523
#> 64: 1.01798232 1.19375008 0.020839662 -0.55216667 0.028935636
#> 65: 0.73506165 0.87121078 0.012275930 -0.04430000 0.012435379
#> 66: 1.30503768 1.53138485 0.006343314 -0.74286667 0.010860272
#> 67: 1.21295497 1.41975706 0.005422182 -0.63310000 0.008331080
#> 68: 0.90801590 1.04589054 0.039209092 -0.66776667 0.057979675
#> 69: 0.91033138 1.05593041 0.005013879 -0.13980000 0.005644554
#> 70: 0.66567051 0.78831518 0.017651636 0.01416667 0.017187956
#> 71: 1.50140284 1.69282924 0.002079722 -0.75150000 0.003379462
#> 72: 0.92221903 1.08549021 0.008896978 -0.26123333 0.011083282
#> 73: 1.13176002 1.31651313 0.004407585 -0.40610000 0.006019440
#> 74: 1.09398883 1.29535998 0.006947625 -0.41440000 0.009103145
#> 75: 1.12573401 1.32679092 0.016745695 -0.69520000 0.023147806
#> 76: 0.99680982 1.14178852 0.003824450 -0.20206667 0.004653230
#> 77: 1.28615912 1.51385999 0.009229506 -0.88796667 0.015867486
#> 78: 0.88779863 1.02895436 0.028449345 -0.53723333 0.043025854
#> 79: 1.00598048 1.16593241 0.034588147 -0.76266667 0.047602705
#> 80: 0.73295675 0.85892056 0.023671502 -0.19190000 0.026969054
#> 81: 0.39317207 0.46194732 0.053626857 0.41883333 0.019690231
#> 82: 0.36948898 0.42607970 0.087295888 0.31943333 0.056703027
#> 83: 0.51602601 0.57087256 0.143455577 -0.22873333 0.167033674
#> 84: 0.41879600 0.45743157 0.212648132 -0.02213333 0.212600715
#> 85: 0.26848103 0.30032538 0.344685074 0.42540000 0.131446499
#> 86: 0.36038724 0.40984406 0.117452572 0.26290000 0.086914958
#> 87: 0.22582416 0.25108633 30.000000000 0.48070000 0.150506549
#> 88: 0.40421325 0.45641866 0.126923290 0.18620000 0.104938005
#> 89: 0.25561534 0.27576952 0.482004214 0.34280000 0.262050505
#> 90: 0.55024130 0.61304737 0.120388567 -0.23676667 0.143651843
#> 91: 0.58191378 0.68366685 0.017638803 0.15233333 0.013459091
#> 92: 0.79635490 0.91959952 0.039776880 -0.45710000 0.052972634
#> 93: 1.13216866 1.33323831 0.006256750 -0.47600000 0.008730800
#> 94: 1.02494127 1.20800058 0.016682174 -0.54256667 0.022466542
#> 95: 0.75049546 0.85590610 0.058794620 -0.48653333 0.079484138
#> 96: 0.82301103 0.96481060 0.025824025 -0.31900000 0.030306953
#> 97: 1.26448110 1.49594653 0.008219032 -0.77343333 0.012547541
#> 98: 0.92251580 1.07425601 0.026077313 -0.49686667 0.037516853
#> 99: 0.80084964 0.89159948 0.096729600 -0.78626667 0.146270629
#> 100: 1.11481342 1.30596053 0.016239553 -0.76026667 0.026434030
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> <num> <num> <num> <num> <num> <num>
#> 1: 0.3651678148 1.0000000 1.9119007 0.9884406 1.660656e-07 0.0045303452
#> 2: 0.2663967900 1.0000000 2.2700932 0.9905292 8.267143e-08 0.0056700663
#> 3: 0.7669777183 1.0000000 3.1437068 0.9914280 5.831599e-08 0.0007996589
#> 4: 0.7468373651 1.0000000 3.3444924 0.9757902 2.207855e-06 0.0014589160
#> 5: 0.5776422640 1.0000000 3.7583023 0.9968734 1.709038e-09 0.0006971243
#> 6: 0.7767392076 1.0000000 0.2541701 0.7382169 9.179004e-03 0.0039751137
#> 7: 0.6856295469 1.0000000 2.2283677 0.9732050 3.149112e-06 0.0020708650
#> 8: 0.6122474630 1.0000000 2.2285708 0.9880579 1.861139e-07 0.0024924890
#> 9: 0.7754650425 1.0000000 2.2889985 0.9888129 1.480842e-07 0.0009916378
#> 10: -0.2226798163 1.0000000 2.2951127 0.9990488 2.654224e-11 0.0024404603
#> 11: 0.6470730550 1.0000000 2.8677996 0.9704197 4.451549e-06 0.0049211098
#> 12: 0.2295353843 1.0000000 3.2287691 0.9908815 7.239884e-08 0.0055504640
#> 13: 0.8985288362 1.0000000 5.0000000 0.8578698 1.082436e-03 0.0017311323
#> 14: 0.7779257424 1.0000000 5.0000000 0.9811907 9.126541e-07 0.0009519863
#> 15: 0.8271028214 1.0000000 2.2446169 0.9693003 5.069529e-06 0.0012425224
#> 16: 0.8069689420 1.0000000 2.1324423 0.9532749 2.205084e-05 0.0019540733
#> 17: 0.6734026973 1.0000000 2.0561031 0.9962473 3.237437e-09 0.0006692208
#> 18: 0.3158838755 1.0000000 2.8537073 0.9979296 4.037965e-10 0.0014073691
#> 19: 0.6786316274 1.0000000 2.6189994 0.9900052 9.981764e-08 0.0015756760
#> 20: 0.7126300563 1.0000000 2.7803450 0.9884951 1.633382e-07 0.0014199653
#> 21: 0.6972688823 1.0000000 2.2630422 0.9939342 1.738238e-08 0.0009119932
#> 22: 0.2671164396 1.0000000 3.2188686 0.9942855 1.410692e-08 0.0033809061
#> 23: 0.5707831317 1.0000000 2.2058511 0.9885236 1.619263e-07 0.0035039079
#> 24: 0.5679295931 1.0000000 2.2341289 0.9974080 8.865540e-10 0.0007253857
#> 25: 0.5830557926 1.0000000 3.0941181 0.9915566 5.531131e-08 0.0020546400
#> 26: 0.5234219383 1.0000000 2.5223390 0.9945689 1.180644e-08 0.0018728900
#> 27: 0.9843851852 0.9843852 0.0001000 0.0000000 5.051366e-01 0.0026667731
#> 28: 0.2627284849 1.0000000 1.7543375 0.9929829 2.894338e-08 0.0058346518
#> 29: 0.8134059397 1.0000000 2.0261477 0.9701477 4.596431e-06 0.0017203009
#> 30: 0.5300584965 1.0000000 2.2706141 0.9915850 5.466156e-08 0.0025042007
#> 31: 0.8175800194 1.0000000 2.9545779 0.9263136 1.086067e-04 0.0047546911
#> 32: 0.8497191486 1.0000000 5.0000000 0.9414806 4.847844e-05 0.0028277725
#> 33: 0.7745509842 1.0000000 5.0000000 0.9905919 8.077212e-08 0.0009703665
#> 34: 0.9091685072 1.0000000 5.0000000 0.8703307 7.851092e-04 0.0036147863
#> 35: 0.5909223718 1.0000000 3.3653065 0.9965291 2.463576e-09 0.0007708945
#> 36: 0.8144193534 1.0000000 3.2484642 0.9602404 1.253272e-05 0.0023079249
#> 37: 0.9874333333 0.9874333 0.0001000 0.0000000 5.226792e-01 0.0045005377
#> 38: 0.6190909106 1.0000000 5.0000000 0.9916347 5.354032e-08 0.0021490509
#> 39: 0.8126203033 1.0000000 2.8923837 0.9340415 7.369655e-05 0.0030096935
#> 40: -0.1100555561 1.0000000 2.0231247 0.9954539 6.335023e-09 0.0101608866
#> 41: 0.0843948493 1.0000000 2.2228625 0.9989540 3.700785e-11 0.0011299281
#> 42: 0.4280422001 1.0000000 2.7144943 0.9939185 1.754023e-08 0.0025486690
#> 43: -0.1044494537 1.0000000 2.4212065 0.9902549 9.135969e-08 0.0134618257
#> 44: -0.1620560072 1.0000000 2.0604060 0.9892455 1.289925e-07 0.0102617483
#> 45: 0.7451155399 1.0000000 2.0612207 0.9805388 1.028230e-06 0.0016676158
#> 46: 0.2444903289 1.0000000 1.7269837 0.9955545 5.857477e-09 0.0035994749
#> 47: 0.1316629628 1.0000000 2.7142277 0.9946978 1.085451e-08 0.0041780160
#> 48: 0.6307693263 1.0000000 2.6162346 0.9927082 3.310784e-08 0.0012196886
#> 49: 0.7222776333 1.0000000 1.3911231 0.9644174 8.498288e-06 0.0035483729
#> 50: -0.7215144153 1.0000000 2.1356334 0.9986787 8.385582e-11 0.0054197260
#> 51: -0.8445230124 1.0000000 2.1530486 0.9970059 1.468626e-09 0.0074471434
#> 52: -0.6348290617 1.0000000 2.9134838 0.9975549 7.227836e-10 0.0105548724
#> 53: -0.5906663271 1.0000000 4.9901264 0.9835173 5.749117e-07 0.0479741017
#> 54: -0.5306044465 1.0000000 4.9947313 0.9909207 7.131558e-08 0.0204750192
#> 55: -0.7932565672 1.0000000 2.1890242 0.9987491 6.923104e-11 0.0064150301
#> 56: -0.4405596014 1.0000000 2.0096850 0.9868501 2.607523e-07 0.0214141959
#> 57: -0.6475910270 1.0000000 2.0345801 0.9915706 5.499090e-08 0.0270484156
#> 58: -0.7531963509 1.0000000 1.8253213 0.9987855 6.243166e-11 0.0057202466
#> 59: -0.3102371436 1.0000000 2.5952204 0.9989539 3.702390e-11 0.0032347548
#> 60: 0.3824493623 1.0000000 2.9294992 0.9857446 3.458839e-07 0.0066776424
#> 61: -0.4169392990 1.0000000 2.4926426 0.9974568 8.294838e-10 0.0090820977
#> 62: -0.3641218697 1.0000000 4.9850173 0.9908614 7.295866e-08 0.0208479700
#> 63: -0.6541862131 1.0000000 2.4231874 0.9914850 5.697009e-08 0.0358041319
#> 64: -0.6074320061 1.0000000 2.4227680 0.9960819 3.765019e-09 0.0174257673
#> 65: -0.0153061841 1.0000000 2.3365273 0.9964806 2.586138e-09 0.0056269403
#> 66: -0.7689648974 1.0000000 1.7320650 0.9970436 1.404914e-09 0.0123458770
#> 67: -0.5835770177 1.0000000 1.8007551 0.9976480 6.309898e-10 0.0073846724
#> 68: -0.6255619766 1.0000000 2.0742923 0.9975373 7.412210e-10 0.0119795999
#> 69: -0.1277776181 1.0000000 1.9207939 0.9938926 1.780359e-08 0.0087658850
#> 70: 0.0342563614 1.0000000 2.6661846 0.9973400 9.707612e-10 0.0042664707
#> 71: -0.7476426517 1.0000000 1.8834936 0.9984594 1.435180e-10 0.0039640590
#> 72: -0.2532259879 1.0000000 1.8648542 0.9995596 1.792360e-12 0.0009511982
#> 73: -0.4137519625 1.0000000 1.9345991 0.9993732 6.163698e-12 0.0014555916
#> 74: -0.4443998175 1.0000000 2.3534208 0.9951423 7.989316e-09 0.0137384037
#> 75: -0.7126817181 1.0000000 2.7365478 0.9986032 1.018578e-10 0.0071007044
#> 76: -0.2065860191 1.0000000 1.7631520 0.9967875 1.879027e-09 0.0045316079
#> 77: -0.8438328827 1.0000000 1.8245692 0.9973253 9.896588e-10 0.0137058624
#> 78: -0.5033105133 1.0000000 1.6835691 0.9980112 3.507995e-10 0.0074336916
#> 79: -0.7350666349 1.0000000 2.8313491 0.9990251 2.892854e-11 0.0055864178
#> 80: -0.1438326892 1.0000000 1.9386164 0.9958942 4.434905e-09 0.0087060442
#> 81: 0.4170287342 1.0000000 1.7926586 0.9981406 2.772138e-10 0.0009814830
#> 82: 0.3413600699 1.0000000 2.6605690 0.9970120 1.458224e-09 0.0025565632
#> 83: -0.1599302533 1.0000000 1.8237894 0.9955606 5.829534e-09 0.0104168368
#> 84: 0.0002979208 1.0000000 2.6726325 0.9985093 1.279117e-10 0.0027912514
#> 85: 0.4295060402 1.0000000 2.0321759 0.9950986 8.243686e-09 0.0029000027
#> 86: 0.3003216477 1.0000000 3.0484446 0.9946346 1.131362e-08 0.0051502481
#> 87: 0.5048265847 1.0000000 3.5683198 0.9917107 5.185758e-08 0.0042469987
#> 88: 0.1831084883 1.0000000 2.3975662 0.9924392 3.758273e-08 0.0100206531
#> 89: 0.3552684841 1.0000000 2.0342894 0.9950033 8.818716e-09 0.0038048777
#> 90: -0.1933830016 1.0000000 1.8507842 0.9967431 1.971582e-09 0.0085515416
#> 91: 0.1860626932 1.0000000 1.7209131 0.9966220 2.240260e-09 0.0032422970
#> 92: -0.4013139858 1.0000000 2.0567782 0.9965388 2.439530e-09 0.0120338036
#> 93: -0.4866785556 1.0000000 2.0400478 0.9952028 7.646630e-09 0.0143425595
#> 94: -0.5517780648 1.0000000 2.4980285 0.9985723 1.099614e-10 0.0059898596
#> 95: -0.4303883285 1.0000000 2.0596328 0.9969133 1.633858e-09 0.0120169616
#> 96: -0.3098387168 1.0000000 3.0125648 0.9977677 5.256069e-10 0.0074113065
#> 97: -0.7490788673 1.0000000 2.1640592 0.9987682 6.560411e-11 0.0055870262
#> 98: -0.5239352601 1.0000000 1.9707233 0.9955609 5.828304e-09 0.0174009206
#> 99: -0.7443040083 1.0000000 2.2046853 0.9985705 1.104466e-10 0.0081610637
#> 100: -0.7340189608 1.0000000 1.8543083 0.9987249 7.403286e-11 0.0064842414
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> GR Sd Avg Fit Type GR GR maxlog10Concentration GR N Conc
#> <num> <char> <num> <int>
#> 1: 0.03203268 DRC3pHillFitModelFixS0 1 9
#> 2: 0.03075240 DRC3pHillFitModelFixS0 1 9
#> 3: 0.02000573 DRC3pHillFitModelFixS0 1 9
#> 4: 0.02214360 DRC3pHillFitModelFixS0 1 9
#> 5: 0.03066180 DRC3pHillFitModelFixS0 1 9
#> 6: 0.02346065 DRC3pHillFitModelFixS0 1 9
#> 7: 0.02679197 DRC3pHillFitModelFixS0 1 9
#> 8: 0.01983125 DRC3pHillFitModelFixS0 1 9
#> 9: 0.01910174 DRC3pHillFitModelFixS0 1 9
#> 10: 0.07130873 DRC3pHillFitModelFixS0 1 9
#> 11: 0.02101516 DRC3pHillFitModelFixS0 1 9
#> 12: 0.03850179 DRC3pHillFitModelFixS0 1 9
#> 13: 0.03205436 DRC3pHillFitModelFixS0 1 9
#> 14: 0.02326291 DRC3pHillFitModelFixS0 1 9
#> 15: 0.02352653 DRC3pHillFitModelFixS0 1 9
#> 16: 0.02344649 DRC3pHillFitModelFixS0 1 9
#> 17: 0.03340578 DRC3pHillFitModelFixS0 1 9
#> 18: 0.03448935 DRC3pHillFitModelFixS0 1 9
#> 19: 0.02377445 DRC3pHillFitModelFixS0 1 9
#> 20: 0.02630609 DRC3pHillFitModelFixS0 1 9
#> 21: 0.02570997 DRC3pHillFitModelFixS0 1 9
#> 22: 0.03926750 DRC3pHillFitModelFixS0 1 9
#> 23: 0.02824974 DRC3pHillFitModelFixS0 1 9
#> 24: 0.02856021 DRC3pHillFitModelFixS0 1 9
#> 25: 0.02557931 DRC3pHillFitModelFixS0 1 9
#> 26: 0.02875531 DRC3pHillFitModelFixS0 1 9
#> 27: 0.02503984 DRCConstantFitResult 1 9
#> 28: 0.03690901 DRC3pHillFitModelFixS0 1 9
#> 29: 0.02418509 DRC3pHillFitModelFixS0 1 9
#> 30: 0.02944348 DRC3pHillFitModelFixS0 1 9
#> 31: 0.02872952 DRC3pHillFitModelFixS0 1 9
#> 32: 0.03452733 DRC3pHillFitModelFixS0 1 9
#> 33: 0.03283285 DRC3pHillFitModelFixS0 1 9
#> 34: 0.02600261 DRC3pHillFitModelFixS0 1 9
#> 35: 0.02690396 DRC3pHillFitModelFixS0 1 9
#> 36: 0.03016809 DRC3pHillFitModelFixS0 1 9
#> 37: 0.02836629 DRCConstantFitResult 1 9
#> 38: 0.02649059 DRC3pHillFitModelFixS0 1 9
#> 39: 0.02525543 DRC3pHillFitModelFixS0 1 9
#> 40: 0.05432540 DRC3pHillFitModelFixS0 1 9
#> 41: 0.04268871 DRC3pHillFitModelFixS0 1 9
#> 42: 0.03167032 DRC3pHillFitModelFixS0 1 9
#> 43: 0.04581144 DRC3pHillFitModelFixS0 1 9
#> 44: 0.04712220 DRC3pHillFitModelFixS0 1 9
#> 45: 0.03663539 DRC3pHillFitModelFixS0 1 9
#> 46: 0.04114510 DRC3pHillFitModelFixS0 1 9
#> 47: 0.02957059 DRC3pHillFitModelFixS0 1 9
#> 48: 0.04836989 DRC3pHillFitModelFixS0 1 9
#> 49: 0.01995472 DRC3pHillFitModelFixS0 1 9
#> 50: 0.09569389 DRC3pHillFitModelFixS0 1 9
#> 51: 0.05883646 DRC3pHillFitModelFixS0 1 9
#> 52: 0.05621152 DRC3pHillFitModelFixS0 1 9
#> 53: 0.06787391 DRC3pHillFitModelFixS0 1 9
#> 54: 0.06158907 DRC3pHillFitModelFixS0 1 9
#> 55: 0.07877147 DRC3pHillFitModelFixS0 1 9
#> 56: 0.06417974 DRC3pHillFitModelFixS0 1 9
#> 57: 0.06360624 DRC3pHillFitModelFixS0 1 9
#> 58: 0.08699730 DRC3pHillFitModelFixS0 1 9
#> 59: 0.03924611 DRC3pHillFitModelFixS0 1 9
#> 60: 0.02995868 DRC3pHillFitModelFixS0 1 9
#> 61: 0.04815310 DRC3pHillFitModelFixS0 1 9
#> 62: 0.05756475 DRC3pHillFitModelFixS0 1 9
#> 63: 0.05772902 DRC3pHillFitModelFixS0 1 9
#> 64: 0.05544735 DRC3pHillFitModelFixS0 1 9
#> 65: 0.04812444 DRC3pHillFitModelFixS0 1 9
#> 66: 0.10139524 DRC3pHillFitModelFixS0 1 9
#> 67: 0.06146191 DRC3pHillFitModelFixS0 1 9
#> 68: 0.05594040 DRC3pHillFitModelFixS0 1 9
#> 69: 0.04122973 DRC3pHillFitModelFixS0 1 9
#> 70: 0.03674990 DRC3pHillFitModelFixS0 1 9
#> 71: 0.07586112 DRC3pHillFitModelFixS0 1 9
#> 72: 0.04007412 DRC3pHillFitModelFixS0 1 9
#> 73: 0.06975153 DRC3pHillFitModelFixS0 1 9
#> 74: 0.03442655 DRC3pHillFitModelFixS0 1 9
#> 75: 0.06771926 DRC3pHillFitModelFixS0 1 9
#> 76: 0.04856655 DRC3pHillFitModelFixS0 1 9
#> 77: 0.06455336 DRC3pHillFitModelFixS0 1 9
#> 78: 0.06514096 DRC3pHillFitModelFixS0 1 9
#> 79: 0.04920195 DRC3pHillFitModelFixS0 1 9
#> 80: 0.05402095 DRC3pHillFitModelFixS0 1 9
#> 81: 0.04906576 DRC3pHillFitModelFixS0 1 9
#> 82: 0.04751873 DRC3pHillFitModelFixS0 1 9
#> 83: 0.04074026 DRC3pHillFitModelFixS0 1 9
#> 84: 0.05740278 DRC3pHillFitModelFixS0 1 9
#> 85: 0.04942568 DRC3pHillFitModelFixS0 1 9
#> 86: 0.04407493 DRC3pHillFitModelFixS0 1 9
#> 87: 0.05235831 DRC3pHillFitModelFixS0 1 9
#> 88: 0.04841497 DRC3pHillFitModelFixS0 1 9
#> 89: 0.05300916 DRC3pHillFitModelFixS0 1 9
#> 90: 0.03421832 DRC3pHillFitModelFixS0 1 9
#> 91: 0.04289095 DRC3pHillFitModelFixS0 1 9
#> 92: 0.05008110 DRC3pHillFitModelFixS0 1 9
#> 93: 0.04267612 DRC3pHillFitModelFixS0 1 9
#> 94: 0.06048658 DRC3pHillFitModelFixS0 1 9
#> 95: 0.05057676 DRC3pHillFitModelFixS0 1 9
#> 96: 0.03418831 DRC3pHillFitModelFixS0 1 9
#> 97: 0.04674118 DRC3pHillFitModelFixS0 1 9
#> 98: 0.04602459 DRC3pHillFitModelFixS0 1 9
#> 99: 0.06333498 DRC3pHillFitModelFixS0 1 9
#> 100: 0.07007818 DRC3pHillFitModelFixS0 1 9
#> GR Sd Avg Fit Type GR GR maxlog10Concentration GR N Conc
#> Fit Source Gnumber Drug Name Drug MOA Duration Clid Cell Line Name
#> <char> <char> <char> <char> <num> <char> <char>
#> 1: gDR G00002 drug_002 moa_A 72 CL00011 cellline_BA
#> 2: gDR G00003 drug_003 moa_A 72 CL00011 cellline_BA
#> 3: gDR G00004 drug_004 moa_A 72 CL00011 cellline_BA
#> 4: gDR G00005 drug_005 moa_A 72 CL00011 cellline_BA
#> 5: gDR G00006 drug_006 moa_A 72 CL00011 cellline_BA
#> 6: gDR G00007 drug_007 moa_A 72 CL00011 cellline_BA
#> 7: gDR G00008 drug_008 moa_A 72 CL00011 cellline_BA
#> 8: gDR G00009 drug_009 moa_A 72 CL00011 cellline_BA
#> 9: gDR G00010 drug_010 moa_A 72 CL00011 cellline_BA
#> 10: gDR G00011 drug_011 moa_B 72 CL00011 cellline_BA
#> 11: gDR G00002 drug_002 moa_A 72 CL00012 cellline_CA
#> 12: gDR G00003 drug_003 moa_A 72 CL00012 cellline_CA
#> 13: gDR G00004 drug_004 moa_A 72 CL00012 cellline_CA
#> 14: gDR G00005 drug_005 moa_A 72 CL00012 cellline_CA
#> 15: gDR G00006 drug_006 moa_A 72 CL00012 cellline_CA
#> 16: gDR G00007 drug_007 moa_A 72 CL00012 cellline_CA
#> 17: gDR G00008 drug_008 moa_A 72 CL00012 cellline_CA
#> 18: gDR G00009 drug_009 moa_A 72 CL00012 cellline_CA
#> 19: gDR G00010 drug_010 moa_A 72 CL00012 cellline_CA
#> 20: gDR G00011 drug_011 moa_B 72 CL00012 cellline_CA
#> 21: gDR G00002 drug_002 moa_A 72 CL00013 cellline_DA
#> 22: gDR G00003 drug_003 moa_A 72 CL00013 cellline_DA
#> 23: gDR G00004 drug_004 moa_A 72 CL00013 cellline_DA
#> 24: gDR G00005 drug_005 moa_A 72 CL00013 cellline_DA
#> 25: gDR G00006 drug_006 moa_A 72 CL00013 cellline_DA
#> 26: gDR G00007 drug_007 moa_A 72 CL00013 cellline_DA
#> 27: gDR G00008 drug_008 moa_A 72 CL00013 cellline_DA
#> 28: gDR G00009 drug_009 moa_A 72 CL00013 cellline_DA
#> 29: gDR G00010 drug_010 moa_A 72 CL00013 cellline_DA
#> 30: gDR G00011 drug_011 moa_B 72 CL00013 cellline_DA
#> 31: gDR G00002 drug_002 moa_A 72 CL00014 cellline_EA
#> 32: gDR G00003 drug_003 moa_A 72 CL00014 cellline_EA
#> 33: gDR G00004 drug_004 moa_A 72 CL00014 cellline_EA
#> 34: gDR G00005 drug_005 moa_A 72 CL00014 cellline_EA
#> 35: gDR G00006 drug_006 moa_A 72 CL00014 cellline_EA
#> 36: gDR G00007 drug_007 moa_A 72 CL00014 cellline_EA
#> 37: gDR G00008 drug_008 moa_A 72 CL00014 cellline_EA
#> 38: gDR G00009 drug_009 moa_A 72 CL00014 cellline_EA
#> 39: gDR G00010 drug_010 moa_A 72 CL00014 cellline_EA
#> 40: gDR G00011 drug_011 moa_B 72 CL00014 cellline_EA
#> 41: gDR G00002 drug_002 moa_A 72 CL00015 cellline_FA
#> 42: gDR G00003 drug_003 moa_A 72 CL00015 cellline_FA
#> 43: gDR G00004 drug_004 moa_A 72 CL00015 cellline_FA
#> 44: gDR G00005 drug_005 moa_A 72 CL00015 cellline_FA
#> 45: gDR G00006 drug_006 moa_A 72 CL00015 cellline_FA
#> 46: gDR G00007 drug_007 moa_A 72 CL00015 cellline_FA
#> 47: gDR G00008 drug_008 moa_A 72 CL00015 cellline_FA
#> 48: gDR G00009 drug_009 moa_A 72 CL00015 cellline_FA
#> 49: gDR G00010 drug_010 moa_A 72 CL00015 cellline_FA
#> 50: gDR G00011 drug_011 moa_B 72 CL00015 cellline_FA
#> 51: gDR G00002 drug_002 moa_A 72 CL00016 cellline_GB
#> 52: gDR G00003 drug_003 moa_A 72 CL00016 cellline_GB
#> 53: gDR G00004 drug_004 moa_A 72 CL00016 cellline_GB
#> 54: gDR G00005 drug_005 moa_A 72 CL00016 cellline_GB
#> 55: gDR G00006 drug_006 moa_A 72 CL00016 cellline_GB
#> 56: gDR G00007 drug_007 moa_A 72 CL00016 cellline_GB
#> 57: gDR G00008 drug_008 moa_A 72 CL00016 cellline_GB
#> 58: gDR G00009 drug_009 moa_A 72 CL00016 cellline_GB
#> 59: gDR G00010 drug_010 moa_A 72 CL00016 cellline_GB
#> 60: gDR G00011 drug_011 moa_B 72 CL00016 cellline_GB
#> 61: gDR G00002 drug_002 moa_A 72 CL00017 cellline_HB
#> 62: gDR G00003 drug_003 moa_A 72 CL00017 cellline_HB
#> 63: gDR G00004 drug_004 moa_A 72 CL00017 cellline_HB
#> 64: gDR G00005 drug_005 moa_A 72 CL00017 cellline_HB
#> 65: gDR G00006 drug_006 moa_A 72 CL00017 cellline_HB
#> 66: gDR G00007 drug_007 moa_A 72 CL00017 cellline_HB
#> 67: gDR G00008 drug_008 moa_A 72 CL00017 cellline_HB
#> 68: gDR G00009 drug_009 moa_A 72 CL00017 cellline_HB
#> 69: gDR G00010 drug_010 moa_A 72 CL00017 cellline_HB
#> 70: gDR G00011 drug_011 moa_B 72 CL00017 cellline_HB
#> 71: gDR G00002 drug_002 moa_A 72 CL00018 cellline_IB
#> 72: gDR G00003 drug_003 moa_A 72 CL00018 cellline_IB
#> 73: gDR G00004 drug_004 moa_A 72 CL00018 cellline_IB
#> 74: gDR G00005 drug_005 moa_A 72 CL00018 cellline_IB
#> 75: gDR G00006 drug_006 moa_A 72 CL00018 cellline_IB
#> 76: gDR G00007 drug_007 moa_A 72 CL00018 cellline_IB
#> 77: gDR G00008 drug_008 moa_A 72 CL00018 cellline_IB
#> 78: gDR G00009 drug_009 moa_A 72 CL00018 cellline_IB
#> 79: gDR G00010 drug_010 moa_A 72 CL00018 cellline_IB
#> 80: gDR G00011 drug_011 moa_B 72 CL00018 cellline_IB
#> 81: gDR G00002 drug_002 moa_A 72 CL00019 cellline_JB
#> 82: gDR G00003 drug_003 moa_A 72 CL00019 cellline_JB
#> 83: gDR G00004 drug_004 moa_A 72 CL00019 cellline_JB
#> 84: gDR G00005 drug_005 moa_A 72 CL00019 cellline_JB
#> 85: gDR G00006 drug_006 moa_A 72 CL00019 cellline_JB
#> 86: gDR G00007 drug_007 moa_A 72 CL00019 cellline_JB
#> 87: gDR G00008 drug_008 moa_A 72 CL00019 cellline_JB
#> 88: gDR G00009 drug_009 moa_A 72 CL00019 cellline_JB
#> 89: gDR G00010 drug_010 moa_A 72 CL00019 cellline_JB
#> 90: gDR G00011 drug_011 moa_B 72 CL00019 cellline_JB
#> 91: gDR G00002 drug_002 moa_A 72 CL00020 cellline_KB
#> 92: gDR G00003 drug_003 moa_A 72 CL00020 cellline_KB
#> 93: gDR G00004 drug_004 moa_A 72 CL00020 cellline_KB
#> 94: gDR G00005 drug_005 moa_A 72 CL00020 cellline_KB
#> 95: gDR G00006 drug_006 moa_A 72 CL00020 cellline_KB
#> 96: gDR G00007 drug_007 moa_A 72 CL00020 cellline_KB
#> 97: gDR G00008 drug_008 moa_A 72 CL00020 cellline_KB
#> 98: gDR G00009 drug_009 moa_A 72 CL00020 cellline_KB
#> 99: gDR G00010 drug_010 moa_A 72 CL00020 cellline_KB
#> 100: gDR G00011 drug_011 moa_B 72 CL00020 cellline_KB
#> Fit Source Gnumber Drug Name Drug MOA Duration Clid Cell Line Name
#> Tissue Reference Division Time RV Mean RV AOC
#> <char> <num> <num> <num>
#> 1: tissue_x 26 0.4466890 0.55331098
#> 2: tissue_x 26 0.3939872 0.60601279
#> 3: tissue_x 26 0.7989283 0.20107172
#> 4: tissue_x 26 0.7292519 0.27074809
#> 5: tissue_x 26 0.5948205 0.40517951
#> 6: tissue_x 26 0.9153135 0.08468651
#> 7: tissue_x 26 0.6627378 0.33726218
#> 8: tissue_x 26 0.6541186 0.34588137
#> 9: tissue_x 26 0.8247285 0.17527151
#> 10: tissue_x 26 0.3682302 0.63176984
#> 11: tissue_x 30 0.6926178 0.30738217
#> 12: tissue_x 30 0.3979780 0.60202205
#> 13: tissue_x 30 0.9100259 0.08997415
#> 14: tissue_x 30 0.7873037 0.21269633
#> 15: tissue_x 30 0.8494189 0.15058108
#> 16: tissue_x 30 0.8169558 0.18304416
#> 17: tissue_x 30 0.7755540 0.22444601
#> 18: tissue_x 30 0.5212853 0.47871472
#> 19: tissue_x 30 0.7463491 0.25365094
#> 20: tissue_x 30 0.7616189 0.23838111
#> 21: tissue_x 34 0.7992747 0.20072525
#> 22: tissue_x 34 0.4668574 0.53314262
#> 23: tissue_x 34 0.7261649 0.27383514
#> 24: tissue_x 34 0.7151504 0.28484957
#> 25: tissue_x 34 0.6956589 0.30434108
#> 26: tissue_x 34 0.6779461 0.32205391
#> 27: tissue_x 34 0.9838111 0.01618889
#> 28: tissue_x 34 0.5806643 0.41933574
#> 29: tissue_x 34 0.8776200 0.12238003
#> 30: tissue_x 34 0.6609849 0.33901514
#> 31: tissue_x 38 0.8710149 0.12898507
#> 32: tissue_x 38 0.9173053 0.08269470
#> 33: tissue_x 38 0.8778150 0.12218503
#> 34: tissue_x 38 0.9437698 0.05623016
#> 35: tissue_x 38 0.7144618 0.28553821
#> 36: tissue_x 38 0.8874428 0.11255721
#> 37: tissue_x 38 0.9883815 0.01161852
#> 38: tissue_x 38 0.7852841 0.21471593
#> 39: tissue_x 38 0.8700763 0.12992370
#> 40: tissue_x 38 0.5865688 0.41343121
#> 41: tissue_x 42 0.4828015 0.51719847
#> 42: tissue_x 42 0.6425053 0.35749468
#> 43: tissue_x 42 0.3805017 0.61949830
#> 44: tissue_x 42 0.2977827 0.70221726
#> 45: tissue_x 42 0.8375294 0.16247062
#> 46: tissue_x 42 0.5962853 0.40371474
#> 47: tissue_x 42 0.4657079 0.53429209
#> 48: tissue_x 42 0.7549529 0.24504707
#> 49: tissue_x 42 0.8372120 0.16278796
#> 50: tissue_x 42 0.2524798 0.74752018
#> 51: tissue_y 46 0.1021560 0.89784398
#> 52: tissue_y 46 0.3319590 0.66804098
#> 53: tissue_y 46 0.2102313 0.78976874
#> 54: tissue_y 46 0.2100452 0.78995479
#> 55: tissue_y 46 0.3146779 0.68532206
#> 56: tissue_y 46 0.2311182 0.76888180
#> 57: tissue_y 46 0.2364875 0.76351250
#> 58: tissue_y 46 0.3235937 0.67640628
#> 59: tissue_y 46 0.4821997 0.51780026
#> 60: tissue_y 46 0.6425491 0.35745090
#> 61: tissue_y 50 0.4403251 0.55967489
#> 62: tissue_y 50 0.3158261 0.68417394
#> 63: tissue_y 50 0.3117162 0.68828381
#> 64: tissue_y 50 0.4144975 0.58550254
#> 65: tissue_y 50 0.5330401 0.46695992
#> 66: tissue_y 50 0.2753604 0.72463961
#> 67: tissue_y 50 0.2988946 0.70110537
#> 68: tissue_y 50 0.4775211 0.52247889
#> 69: tissue_y 50 0.4307934 0.56920661
#> 70: tissue_y 50 0.5740133 0.42598675
#> 71: tissue_y 54 0.1817987 0.81820132
#> 72: tissue_y 54 0.4557736 0.54422640
#> 73: tissue_y 54 0.3473656 0.65263436
#> 74: tissue_y 54 0.3722520 0.62774797
#> 75: tissue_y 54 0.3820939 0.61790607
#> 76: tissue_y 54 0.4088002 0.59119981
#> 77: tissue_y 54 0.3086007 0.69139927
#> 78: tissue_y 54 0.4906996 0.50930040
#> 79: tissue_y 54 0.4496388 0.55036124
#> 80: tissue_y 54 0.5613320 0.43866803
#> 81: tissue_z 58 0.7645125 0.23548748
#> 82: tissue_z 58 0.7799746 0.22002537
#> 83: tissue_z 58 0.7029485 0.29705152
#> 84: tissue_z 58 0.7566058 0.24339421
#> 85: tissue_z 58 0.8388170 0.16118297
#> 86: tissue_z 58 0.7862239 0.21377605
#> 87: tissue_z 58 0.8640795 0.13592048
#> 88: tissue_z 58 0.7614460 0.23855403
#> 89: tissue_z 58 0.8471580 0.15284198
#> 90: tissue_z 58 0.6842658 0.31573420
#> 91: tissue_z 62 0.6737095 0.32629051
#> 92: tissue_z 62 0.5683750 0.43162499
#> 93: tissue_z 62 0.3916886 0.60831136
#> 94: tissue_z 62 0.4519141 0.54808592
#> 95: tissue_z 62 0.5938560 0.40614404
#> 96: tissue_z 62 0.5525910 0.44740898
#> 97: tissue_z 62 0.3356482 0.66435184
#> 98: tissue_z 62 0.5045079 0.49549211
#> 99: tissue_z 62 0.5769999 0.42300010
#> 100: tissue_z 62 0.4117805 0.58821946
#> Tissue Reference Division Time RV Mean RV AOC
#> RV AOC within set range IC50 E Max EC50 E Inf
#> <num> <num> <num> <num> <num>
#> 1: 0.62771204 0.007253171 0.32793333 0.003795893 0.34682665
#> 2: 0.69549935 0.005655581 0.27413333 0.003962986 0.28319787
#> 3: 0.23854321 30.000000000 0.70636667 0.016546380 0.71001484
#> 4: 0.30829556 30.000000000 0.67963333 0.003304929 0.68717703
#> 5: 0.47306641 30.000000000 0.50873333 0.004129702 0.51907021
#> 6: 0.09862965 30.000000000 0.86246667 0.023423073 0.87074092
#> 7: 0.37222482 30.000000000 0.59466667 0.002397623 0.62344087
#> 8: 0.40814181 30.000000000 0.56796667 0.008060179 0.55098117
#> 9: 0.20515620 30.000000000 0.72036667 0.031276165 0.71953596
#> 10: 0.74702096 0.019384886 0.07090000 0.018136158 0.07568110
#> 11: 0.35949454 30.000000000 0.63853333 0.004774753 0.62816339
#> 12: 0.68371983 0.003821711 0.27726667 0.003008201 0.31309370
#> 13: 0.10791352 30.000000000 0.87040000 0.008254080 0.88286917
#> 14: 0.24486763 30.000000000 0.77096667 0.003354506 0.75408088
#> 15: 0.17760851 30.000000000 0.80546667 0.007866347 0.80517426
#> 16: 0.20901519 30.000000000 0.76806667 0.003815689 0.78433529
#> 17: 0.26336442 30.000000000 0.64960000 0.025909149 0.65208728
#> 18: 0.56881144 0.015334114 0.35873333 0.009338353 0.36576263
#> 19: 0.30161904 30.000000000 0.65570000 0.010664967 0.65748115
#> 20: 0.28326524 30.000000000 0.68473333 0.008285395 0.68946503
#> 21: 0.23709408 30.000000000 0.69726667 0.018014759 0.70662235
#> 22: 0.61173591 0.005175017 0.36916667 0.003431788 0.38161495
#> 23: 0.32331797 30.000000000 0.60056667 0.017991972 0.59983667
#> 24: 0.33700199 30.000000000 0.59763333 0.014539308 0.59720052
#> 25: 0.36205275 30.000000000 0.59926667 0.007397397 0.60975201
#> 26: 0.38244556 30.000000000 0.55096667 0.011148175 0.56228258
#> 27: 0.01618889 30.000000000 0.97033333 NA 0.98381111
#> 28: 0.49233133 0.044349772 0.35713333 0.019771994 0.37777983
#> 29: 0.14379727 30.000000000 0.82200000 0.023835769 0.81289660
#> 30: 0.39942016 30.000000000 0.55890000 0.007078033 0.56771316
#> 31: 0.15337431 30.000000000 0.82480000 0.007404640 0.83458186
#> 32: 0.09639032 30.000000000 0.84193333 0.038642612 0.86268158
#> 33: 0.14245939 30.000000000 0.78713333 0.038237333 0.79748718
#> 34: 0.06647635 30.000000000 0.91773333 0.020858876 0.91588511
#> 35: 0.33774750 30.000000000 0.64843333 0.005482997 0.64836791
#> 36: 0.13302031 30.000000000 0.80563333 0.020762148 0.83175068
#> 37: 0.01161852 30.000000000 0.97366667 NA 0.98838148
#> 38: 0.25298214 30.000000000 0.66726667 0.024503188 0.67026768
#> 39: 0.15434173 30.000000000 0.83416667 0.008516796 0.83009341
#> 40: 0.47176921 0.103693590 0.22530000 0.077874576 0.21531639
#> 41: 0.60667873 0.010722078 0.33776667 0.006294304 0.35077573
#> 42: 0.41943708 30.000000000 0.55923333 0.005301487 0.56156486
#> 43: 0.71885082 0.006229871 0.23093333 0.004661971 0.25237654
#> 44: 0.76597220 0.002756447 0.20110000 0.002085738 0.22629021
#> 45: 0.19070324 30.000000000 0.77860000 0.007310403 0.79181981
#> 46: 0.47449665 0.041965155 0.41790000 0.012099942 0.44418366
#> 47: 0.61134861 0.005912214 0.36410000 0.003552790 0.37709397
#> 48: 0.28487547 30.000000000 0.70263333 0.004561251 0.70521133
#> 49: 0.18968302 30.000000000 0.76936667 0.012481407 0.77448135
#> 50: 0.88177300 0.007884476 0.02790000 0.007623490 0.03706278
#> 51: 0.97368081 0.001975139 0.01156667 0.001941693 0.02047816
#> 52: 0.79488065 0.013697468 0.06936667 0.013030558 0.07094849
#> 53: 0.90450614 0.003811979 0.06773333 0.003585337 0.07825779
#> 54: 0.88824111 0.003197359 0.08630000 0.002932087 0.09935284
#> 55: 0.81208812 0.014902515 0.01756667 0.014508564 0.03128655
#> 56: 0.84899908 0.002887489 0.13533333 0.002461805 0.13678567
#> 57: 0.88498708 0.005396956 0.06396667 0.005034691 0.06871316
#> 58: 0.79810483 0.015444308 0.04450000 0.014793650 0.04081369
#> 59: 0.60821155 0.032638339 0.17626667 0.027413659 0.18981432
#> 60: 0.42057145 30.000000000 0.57070000 0.005350482 0.56115445
#> 61: 0.66129430 0.023097263 0.17430000 0.019657332 0.17067228
#> 62: 0.79476913 0.004922621 0.16046667 0.004218802 0.18540041
#> 63: 0.81859408 0.010326282 0.07083333 0.009658844 0.08373933
#> 64: 0.68838500 0.027637201 0.11686667 0.025274379 0.09621464
#> 65: 0.55422115 0.019427772 0.34556667 0.011549019 0.36203554
#> 66: 0.84954049 0.009224850 0.05420000 0.008730319 0.04790721
#> 67: 0.81877562 0.007990484 0.08710000 0.007043304 0.10560283
#> 68: 0.60461228 0.054323446 0.07786667 0.049549089 0.09209706
#> 69: 0.65813446 0.008297512 0.29680000 0.005151240 0.30315714
#> 70: 0.50486302 0.028380166 0.37660000 0.016287291 0.38712847
#> 71: 0.91385902 0.003121891 0.06380000 0.002908151 0.06403699
#> 72: 0.64062126 0.015278400 0.26503333 0.010185821 0.26943207
#> 73: 0.75662897 0.007000949 0.19893333 0.005440592 0.19547452
#> 74: 0.74215883 0.010133991 0.19443333 0.008351180 0.18112340
#> 75: 0.72975315 0.022055538 0.08350000 0.020776435 0.07624990
#> 76: 0.67444555 0.007029613 0.29376667 0.004287339 0.29150899
#> 77: 0.81546273 0.013769074 0.02206667 0.013254560 0.03556904
#> 78: 0.59207687 0.047179141 0.14253333 0.037914493 0.15699796
#> 79: 0.63963532 0.045215408 0.05843333 0.043031281 0.06820615
#> 80: 0.51481053 0.042486343 0.29903333 0.025152816 0.32334398
#> 81: 0.27674936 30.000000000 0.65316667 0.019245011 0.65209837
#> 82: 0.25385986 30.000000000 0.59670000 0.055689068 0.60914083
#> 83: 0.32948401 0.295080096 0.30650000 0.158198620 0.34093110
#> 84: 0.26629466 0.413743153 0.41173333 0.206332658 0.42342449
#> 85: 0.18043264 30.000000000 0.65686667 0.129212028 0.65883941
#> 86: 0.24324624 30.000000000 0.56523333 0.085602158 0.58627595
#> 87: 0.15119347 30.000000000 0.68853333 0.149067206 0.70263542
#> 88: 0.26963522 30.000000000 0.52300000 0.102208367 0.52064083
#> 89: 0.16513000 30.000000000 0.61000000 0.256158972 0.61685311
#> 90: 0.35272441 0.236075692 0.30246667 0.135223132 0.32473738
#> 91: 0.38341599 30.000000000 0.52713333 0.013128583 0.54530841
#> 92: 0.49907540 0.070162438 0.22003333 0.050619652 0.24695917
#> 93: 0.71651338 0.010695136 0.21133333 0.008294007 0.20699055
#> 94: 0.64651950 0.025509994 0.18053333 0.021456873 0.17635164
#> 95: 0.46394440 0.102279380 0.20620000 0.075806992 0.23335970
#> 96: 0.52483930 0.039032319 0.28623333 0.029513143 0.29115866
#> 97: 0.78615325 0.012891906 0.08013333 0.011778656 0.08958619
#> 98: 0.57777110 0.045034344 0.20156667 0.035484367 0.18949638
#> 99: 0.47231044 0.150209032 0.07513333 0.137152296 0.09235428
#> 100: 0.69005808 0.027440547 0.08603333 0.024485958 0.09662172
#> RV AOC within set range IC50 E Max EC50 E Inf
#> E0 h RV RV R2 RV p Value RV Rss RV Sd Avg
#> <num> <num> <num> <num> <num> <num>
#> 1: 1.0000000 1.827031 0.9924695 3.705769e-08 0.0027788222 0.02424423
#> 2: 1.0000000 2.349599 0.9958511 4.600131e-09 0.0021823404 0.02195104
#> 3: 1.0000000 3.159939 0.9918874 4.809026e-08 0.0011623407 0.02315049
#> 4: 1.0000000 2.869796 0.9788260 1.381366e-06 0.0018580999 0.02433754
#> 5: 1.0000000 3.829228 0.9978624 4.515583e-10 0.0006002563 0.02914251
#> 6: 1.0000000 1.396984 0.9622053 1.049565e-05 0.0010089336 0.03095134
#> 7: 1.0000000 2.285910 0.9796018 1.212200e-06 0.0021497125 0.02851709
#> 8: 1.0000000 2.239456 0.9917851 5.024614e-08 0.0022433269 0.02120201
#> 9: 1.0000000 2.336379 0.9894868 1.191422e-07 0.0014484927 0.02368805
#> 10: 1.0000000 2.464822 0.9985658 1.117095e-10 0.0020514821 0.02467602
#> 11: 1.0000000 2.919115 0.9767620 1.912923e-06 0.0042266456 0.02026923
#> 12: 1.0000000 4.111036 0.9952426 7.426431e-09 0.0021879035 0.02564250
#> 13: 1.0000000 5.000000 0.8541039 1.186186e-03 0.0023608040 0.03624754
#> 14: 1.0000000 5.000000 0.9832682 6.059013e-07 0.0010166387 0.02462014
#> 15: 1.0000000 2.241526 0.9725466 3.428366e-06 0.0013962272 0.02581034
#> 16: 1.0000000 2.178830 0.9569420 1.656493e-05 0.0022229434 0.02491576
#> 17: 1.0000000 2.036162 0.9968137 1.825950e-09 0.0006398224 0.03482572
#> 18: 1.0000000 2.651473 0.9984890 1.340914e-10 0.0008475955 0.02606777
#> 19: 1.0000000 2.703715 0.9917990 4.995008e-08 0.0014512290 0.02352835
#> 20: 1.0000000 2.768447 0.9901512 9.480595e-08 0.0014125688 0.02706624
#> 21: 1.0000000 2.255304 0.9949255 9.308666e-09 0.0007114611 0.02403599
#> 22: 1.0000000 3.507307 0.9962628 3.190785e-09 0.0015119310 0.02698012
#> 23: 1.0000000 2.193421 0.9909905 6.941415e-08 0.0023665643 0.02577172
#> 24: 1.0000000 2.214172 0.9973294 9.843622e-10 0.0006363358 0.02525688
#> 25: 1.0000000 3.069376 0.9934571 2.265652e-08 0.0013783062 0.02269828
#> 26: 1.0000000 2.535963 0.9960204 3.976072e-09 0.0011374563 0.02402262
#> 27: 0.9838111 0.000100 0.0000000 4.979239e-01 0.0029436207 0.02620160
#> 28: 1.0000000 1.743888 0.9951205 8.115446e-09 0.0027937482 0.02903764
#> 29: 1.0000000 2.039182 0.9729143 3.270314e-06 0.0015619403 0.02427360
#> 30: 1.0000000 2.322658 0.9935786 2.121800e-08 0.0015913349 0.02469797
#> 31: 1.0000000 3.013686 0.9253169 1.138357e-04 0.0040117584 0.02546309
#> 32: 1.0000000 5.000000 0.9442965 4.079327e-05 0.0022454435 0.03159417
#> 33: 1.0000000 5.000000 0.9908466 7.337283e-08 0.0007607914 0.02897195
#> 34: 1.0000000 5.000000 0.8671881 8.537470e-04 0.0032197577 0.02385616
#> 35: 1.0000000 3.372144 0.9971479 1.238942e-09 0.0004630470 0.02145847
#> 36: 1.0000000 3.262119 0.9613882 1.131147e-05 0.0018341727 0.02696312
#> 37: 0.9883815 0.000100 0.0000000 3.003192e-01 0.0034434491 0.02670075
#> 38: 1.0000000 5.000000 0.9917875 5.019502e-08 0.0015741830 0.02216258
#> 39: 1.0000000 2.706836 0.9367858 6.351119e-05 0.0023356139 0.02237141
#> 40: 1.0000000 1.966991 0.9976196 6.580954e-10 0.0026451685 0.03512306
#> 41: 1.0000000 2.270037 0.9991870 1.532058e-11 0.0004309408 0.02583750
#> 42: 1.0000000 2.740291 0.9951004 8.232852e-09 0.0011916253 0.02329129
#> 43: 1.0000000 2.423790 0.9933838 2.355796e-08 0.0039254874 0.02481987
#> 44: 1.0000000 2.161036 0.9941359 1.544166e-08 0.0022236840 0.02302050
#> 45: 1.0000000 2.065713 0.9820954 7.680224e-07 0.0010163372 0.02911082
#> 46: 1.0000000 1.763005 0.9967096 2.043397e-09 0.0014121632 0.02750852
#> 47: 1.0000000 2.755200 0.9964623 2.633342e-09 0.0013740389 0.01788683
#> 48: 1.0000000 2.642410 0.9930514 2.796599e-08 0.0007360079 0.03663836
#> 49: 1.0000000 1.432588 0.9629959 9.747072e-06 0.0024229473 0.01589380
#> 50: 1.0000000 2.287981 0.9995991 1.290124e-12 0.0004814205 0.02605429
#> 51: 1.0000000 2.448673 0.9992976 9.185549e-12 0.0004198723 0.01347179
#> 52: 1.0000000 3.065907 0.9982225 2.367642e-10 0.0023752601 0.02166174
#> 53: 1.0000000 2.776919 0.9969366 1.591078e-09 0.0027166839 0.02379256
#> 54: 1.0000000 2.557727 0.9990998 2.188336e-11 0.0006322521 0.02440520
#> 55: 1.0000000 2.411884 0.9989330 3.968447e-11 0.0015443091 0.02854761
#> 56: 1.0000000 2.003949 0.9940489 1.625854e-08 0.0030714525 0.02768624
#> 57: 1.0000000 2.127642 0.9977338 5.540498e-10 0.0021463145 0.02021322
#> 58: 1.0000000 1.978326 0.9993449 7.196834e-12 0.0008883295 0.02920943
#> 59: 1.0000000 2.736872 0.9994655 3.530406e-12 0.0006289186 0.02246907
#> 60: 1.0000000 2.940905 0.9878645 1.968793e-07 0.0028158117 0.02061972
#> 61: 1.0000000 2.589266 0.9980176 3.468423e-10 0.0024284335 0.02328919
#> 62: 1.0000000 3.002839 0.9978019 4.979588e-10 0.0016845191 0.02727108
#> 63: 1.0000000 2.743208 0.9966324 2.216266e-09 0.0042541545 0.02529924
#> 64: 1.0000000 2.391418 0.9979799 3.705174e-10 0.0027829406 0.02494556
#> 65: 1.0000000 2.475686 0.9965915 2.311928e-09 0.0021365407 0.02789728
#> 66: 1.0000000 1.827993 0.9990550 2.594026e-11 0.0010823145 0.03555896
#> 67: 1.0000000 1.880336 0.9988034 5.926379e-11 0.0011411900 0.02594352
#> 68: 1.0000000 2.213005 0.9983842 1.695655e-10 0.0024649969 0.02468871
#> 69: 1.0000000 1.955457 0.9958787 4.494010e-09 0.0021801892 0.02364677
#> 70: 1.0000000 2.680251 0.9975327 7.461140e-10 0.0015856291 0.02115656
#> 71: 1.0000000 1.932432 0.9991981 1.460497e-11 0.0005404075 0.02845357
#> 72: 1.0000000 1.909176 0.9995183 2.452621e-12 0.0003467009 0.02094491
#> 73: 1.0000000 1.966440 0.9994474 3.967682e-12 0.0004025462 0.03261254
#> 74: 1.0000000 2.324659 0.9966253 2.232695e-09 0.0029765716 0.01687243
#> 75: 1.0000000 2.769539 0.9992905 9.514306e-12 0.0010395275 0.02890447
#> 76: 1.0000000 1.769006 0.9973898 9.085852e-10 0.0012150473 0.02575115
#> 77: 1.0000000 1.937726 0.9990756 2.401496e-11 0.0012638360 0.02401299
#> 78: 1.0000000 1.723879 0.9986513 9.008741e-11 0.0015699934 0.03358047
#> 79: 1.0000000 2.962191 0.9993880 5.670183e-12 0.0010056258 0.02405125
#> 80: 1.0000000 1.984697 0.9960406 3.905880e-09 0.0029102882 0.03048010
#> 81: 1.0000000 1.796886 0.9981400 2.775246e-10 0.0003485312 0.02875185
#> 82: 1.0000000 2.665200 0.9969579 1.552798e-09 0.0009178606 0.02807435
#> 83: 1.0000000 1.837149 0.9963409 2.963407e-09 0.0027780381 0.02321208
#> 84: 1.0000000 2.696824 0.9985293 1.219970e-10 0.0009193400 0.03321846
#> 85: 1.0000000 2.006733 0.9949262 9.303663e-09 0.0010726159 0.02970061
#> 86: 1.0000000 3.117706 0.9948828 9.585348e-09 0.0017207801 0.02613007
#> 87: 1.0000000 3.578535 0.9913418 6.039404e-08 0.0016026034 0.03144202
#> 88: 1.0000000 2.321359 0.9918926 4.798189e-08 0.0037064480 0.02837621
#> 89: 1.0000000 2.023378 0.9948254 9.967103e-09 0.0013976276 0.03160124
#> 90: 1.0000000 1.881323 0.9969943 1.488693e-09 0.0025492991 0.01994518
#> 91: 1.0000000 1.733740 0.9968381 1.777626e-09 0.0009436559 0.02358830
#> 92: 1.0000000 2.086104 0.9970699 1.361674e-09 0.0029342522 0.02633392
#> 93: 1.0000000 2.101833 0.9960998 3.705262e-09 0.0032832350 0.02144606
#> 94: 1.0000000 2.513797 0.9988743 4.786781e-11 0.0013274649 0.03026998
#> 95: 1.0000000 2.099067 0.9968471 1.759891e-09 0.0035472702 0.02618347
#> 96: 1.0000000 3.122947 0.9976141 6.634336e-10 0.0023287486 0.01817215
#> 97: 1.0000000 2.186258 0.9990599 2.547129e-11 0.0011386370 0.02235921
#> 98: 1.0000000 1.998935 0.9961207 3.636093e-09 0.0042739653 0.02298094
#> 99: 1.0000000 2.245643 0.9988156 5.718652e-11 0.0018424204 0.03151223
#> 100: 1.0000000 1.884916 0.9986615 8.773134e-11 0.0018446214 0.03335063
#> E0 h RV RV R2 RV p Value RV Rss RV Sd Avg
#> Fit Type RV RV maxlog10Concentration RV N Conc
#> <char> <num> <int>
#> 1: DRC3pHillFitModelFixS0 1 9
#> 2: DRC3pHillFitModelFixS0 1 9
#> 3: DRC3pHillFitModelFixS0 1 9
#> 4: DRC3pHillFitModelFixS0 1 9
#> 5: DRC3pHillFitModelFixS0 1 9
#> 6: DRC3pHillFitModelFixS0 1 9
#> 7: DRC3pHillFitModelFixS0 1 9
#> 8: DRC3pHillFitModelFixS0 1 9
#> 9: DRC3pHillFitModelFixS0 1 9
#> 10: DRC3pHillFitModelFixS0 1 9
#> 11: DRC3pHillFitModelFixS0 1 9
#> 12: DRC3pHillFitModelFixS0 1 9
#> 13: DRC3pHillFitModelFixS0 1 9
#> 14: DRC3pHillFitModelFixS0 1 9
#> 15: DRC3pHillFitModelFixS0 1 9
#> 16: DRC3pHillFitModelFixS0 1 9
#> 17: DRC3pHillFitModelFixS0 1 9
#> 18: DRC3pHillFitModelFixS0 1 9
#> 19: DRC3pHillFitModelFixS0 1 9
#> 20: DRC3pHillFitModelFixS0 1 9
#> 21: DRC3pHillFitModelFixS0 1 9
#> 22: DRC3pHillFitModelFixS0 1 9
#> 23: DRC3pHillFitModelFixS0 1 9
#> 24: DRC3pHillFitModelFixS0 1 9
#> 25: DRC3pHillFitModelFixS0 1 9
#> 26: DRC3pHillFitModelFixS0 1 9
#> 27: DRCConstantFitResult 1 9
#> 28: DRC3pHillFitModelFixS0 1 9
#> 29: DRC3pHillFitModelFixS0 1 9
#> 30: DRC3pHillFitModelFixS0 1 9
#> 31: DRC3pHillFitModelFixS0 1 9
#> 32: DRC3pHillFitModelFixS0 1 9
#> 33: DRC3pHillFitModelFixS0 1 9
#> 34: DRC3pHillFitModelFixS0 1 9
#> 35: DRC3pHillFitModelFixS0 1 9
#> 36: DRC3pHillFitModelFixS0 1 9
#> 37: DRCConstantFitResult 1 9
#> 38: DRC3pHillFitModelFixS0 1 9
#> 39: DRC3pHillFitModelFixS0 1 9
#> 40: DRC3pHillFitModelFixS0 1 9
#> 41: DRC3pHillFitModelFixS0 1 9
#> 42: DRC3pHillFitModelFixS0 1 9
#> 43: DRC3pHillFitModelFixS0 1 9
#> 44: DRC3pHillFitModelFixS0 1 9
#> 45: DRC3pHillFitModelFixS0 1 9
#> 46: DRC3pHillFitModelFixS0 1 9
#> 47: DRC3pHillFitModelFixS0 1 9
#> 48: DRC3pHillFitModelFixS0 1 9
#> 49: DRC3pHillFitModelFixS0 1 9
#> 50: DRC3pHillFitModelFixS0 1 9
#> 51: DRC3pHillFitModelFixS0 1 9
#> 52: DRC3pHillFitModelFixS0 1 9
#> 53: DRC3pHillFitModelFixS0 1 9
#> 54: DRC3pHillFitModelFixS0 1 9
#> 55: DRC3pHillFitModelFixS0 1 9
#> 56: DRC3pHillFitModelFixS0 1 9
#> 57: DRC3pHillFitModelFixS0 1 9
#> 58: DRC3pHillFitModelFixS0 1 9
#> 59: DRC3pHillFitModelFixS0 1 9
#> 60: DRC3pHillFitModelFixS0 1 9
#> 61: DRC3pHillFitModelFixS0 1 9
#> 62: DRC3pHillFitModelFixS0 1 9
#> 63: DRC3pHillFitModelFixS0 1 9
#> 64: DRC3pHillFitModelFixS0 1 9
#> 65: DRC3pHillFitModelFixS0 1 9
#> 66: DRC3pHillFitModelFixS0 1 9
#> 67: DRC3pHillFitModelFixS0 1 9
#> 68: DRC3pHillFitModelFixS0 1 9
#> 69: DRC3pHillFitModelFixS0 1 9
#> 70: DRC3pHillFitModelFixS0 1 9
#> 71: DRC3pHillFitModelFixS0 1 9
#> 72: DRC3pHillFitModelFixS0 1 9
#> 73: DRC3pHillFitModelFixS0 1 9
#> 74: DRC3pHillFitModelFixS0 1 9
#> 75: DRC3pHillFitModelFixS0 1 9
#> 76: DRC3pHillFitModelFixS0 1 9
#> 77: DRC3pHillFitModelFixS0 1 9
#> 78: DRC3pHillFitModelFixS0 1 9
#> 79: DRC3pHillFitModelFixS0 1 9
#> 80: DRC3pHillFitModelFixS0 1 9
#> 81: DRC3pHillFitModelFixS0 1 9
#> 82: DRC3pHillFitModelFixS0 1 9
#> 83: DRC3pHillFitModelFixS0 1 9
#> 84: DRC3pHillFitModelFixS0 1 9
#> 85: DRC3pHillFitModelFixS0 1 9
#> 86: DRC3pHillFitModelFixS0 1 9
#> 87: DRC3pHillFitModelFixS0 1 9
#> 88: DRC3pHillFitModelFixS0 1 9
#> 89: DRC3pHillFitModelFixS0 1 9
#> 90: DRC3pHillFitModelFixS0 1 9
#> 91: DRC3pHillFitModelFixS0 1 9
#> 92: DRC3pHillFitModelFixS0 1 9
#> 93: DRC3pHillFitModelFixS0 1 9
#> 94: DRC3pHillFitModelFixS0 1 9
#> 95: DRC3pHillFitModelFixS0 1 9
#> 96: DRC3pHillFitModelFixS0 1 9
#> 97: DRC3pHillFitModelFixS0 1 9
#> 98: DRC3pHillFitModelFixS0 1 9
#> 99: DRC3pHillFitModelFixS0 1 9
#> 100: DRC3pHillFitModelFixS0 1 9
#> Fit Type RV RV maxlog10Concentration RV N Conc
convert_se_assay_to_custom_dt(se, "Metrics", output_table = "Metrics_raw")
#> r Id c Id GR Mean
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.472929759
#> 2: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.393219859
#> 3: G00004_drug_004_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.839327136
#> 4: G00005_drug_005_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.781708106
#> 5: G00006_drug_006_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.646759184
#> 6: G00007_drug_007_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.937436799
#> 7: G00008_drug_008_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.720542898
#> 8: G00009_drug_009_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.704849585
#> 9: G00010_drug_010_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.860814168
#> 10: G00011_drug_011_moa_B_72 CL00011_cellline_BA_tissue_x_26 0.207159460
#> 11: G00002_drug_002_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.710189522
#> 12: G00003_drug_003_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.332747901
#> 13: G00004_drug_004_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.922099383
#> 14: G00005_drug_005_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.808309237
#> 15: G00006_drug_006_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.866903473
#> 16: G00007_drug_007_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.836985050
#> 17: G00008_drug_008_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.791435957
#> 18: G00009_drug_009_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.491313620
#> 19: G00010_drug_010_moa_A_72 CL00012_cellline_CA_tissue_x_30 0.763749516
#> 20: G00011_drug_011_moa_B_72 CL00012_cellline_CA_tissue_x_30 0.780650008
#> 21: G00002_drug_002_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.794248968
#> 22: G00003_drug_003_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.374827861
#> 23: G00004_drug_004_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.709167535
#> 24: G00005_drug_005_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.697104582
#> 25: G00006_drug_006_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.676875616
#> 26: G00007_drug_007_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.652414714
#> 27: G00008_drug_008_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.984385185
#> 28: G00009_drug_009_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.514432888
#> 29: G00010_drug_010_moa_A_72 CL00013_cellline_DA_tissue_x_34 0.878482510
#> 30: G00011_drug_011_moa_B_72 CL00013_cellline_DA_tissue_x_34 0.634715550
#> 31: G00002_drug_002_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.858014876
#> 32: G00003_drug_003_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.909591493
#> 33: G00004_drug_004_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.864237280
#> 34: G00005_drug_005_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.939294715
#> 35: G00006_drug_006_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.669107225
#> 36: G00007_drug_007_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.876104175
#> 37: G00008_drug_008_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.987433333
#> 38: G00009_drug_009_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.752739905
#> 39: G00010_drug_010_moa_A_72 CL00014_cellline_EA_tissue_x_38 0.857326327
#> 40: G00011_drug_011_moa_B_72 CL00014_cellline_EA_tissue_x_38 0.435872637
#> 41: G00002_drug_002_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.280017800
#> 42: G00003_drug_003_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.536315316
#> 43: G00004_drug_004_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.097480450
#> 44: G00005_drug_005_moa_A_72 CL00015_cellline_FA_tissue_x_42 -0.038391125
#> 45: G00006_drug_006_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.801673120
#> 46: G00007_drug_007_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.459163515
#> 47: G00008_drug_008_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.261931402
#> 48: G00009_drug_009_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.694250375
#> 49: G00010_drug_010_moa_A_72 CL00015_cellline_FA_tissue_x_42 0.800908530
#> 50: G00011_drug_011_moa_B_72 CL00015_cellline_FA_tissue_x_42 -0.288561464
#> 51: G00002_drug_002_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.645509596
#> 52: G00003_drug_003_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.151209620
#> 53: G00004_drug_004_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.362400138
#> 54: G00005_drug_005_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.328454740
#> 55: G00006_drug_006_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.224809588
#> 56: G00007_drug_007_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.260281000
#> 57: G00008_drug_008_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.314141961
#> 58: G00009_drug_009_moa_A_72 CL00016_cellline_GB_tissue_y_46 -0.188230693
#> 59: G00010_drug_010_moa_A_72 CL00016_cellline_GB_tissue_y_46 0.177463519
#> 60: G00011_drug_011_moa_B_72 CL00016_cellline_GB_tissue_y_46 0.499202800
#> 61: G00002_drug_002_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.059329643
#> 62: G00003_drug_003_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.156760855
#> 63: G00004_drug_004_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.218107316
#> 64: G00005_drug_005_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.017982323
#> 65: G00006_drug_006_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.264938349
#> 66: G00007_drug_007_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.305037682
#> 67: G00008_drug_008_moa_A_72 CL00017_cellline_HB_tissue_y_50 -0.212954966
#> 68: G00009_drug_009_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.091984103
#> 69: G00010_drug_010_moa_A_72 CL00017_cellline_HB_tissue_y_50 0.089668620
#> 70: G00011_drug_011_moa_B_72 CL00017_cellline_HB_tissue_y_50 0.334329487
#> 71: G00002_drug_002_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.501402843
#> 72: G00003_drug_003_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.077780973
#> 73: G00004_drug_004_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.131760019
#> 74: G00005_drug_005_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.093988826
#> 75: G00006_drug_006_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.125734009
#> 76: G00007_drug_007_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.003190178
#> 77: G00008_drug_008_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.286159124
#> 78: G00009_drug_009_moa_A_72 CL00018_cellline_IB_tissue_y_54 0.112201368
#> 79: G00010_drug_010_moa_A_72 CL00018_cellline_IB_tissue_y_54 -0.005980476
#> 80: G00011_drug_011_moa_B_72 CL00018_cellline_IB_tissue_y_54 0.267043249
#> 81: G00002_drug_002_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.606827931
#> 82: G00003_drug_003_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.630511020
#> 83: G00004_drug_004_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.483973989
#> 84: G00005_drug_005_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.581204001
#> 85: G00006_drug_006_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.731518966
#> 86: G00007_drug_007_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.639612759
#> 87: G00008_drug_008_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.774175841
#> 88: G00009_drug_009_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.595786753
#> 89: G00010_drug_010_moa_A_72 CL00019_cellline_JB_tissue_z_58 0.744384655
#> 90: G00011_drug_011_moa_B_72 CL00019_cellline_JB_tissue_z_58 0.449758703
#> 91: G00002_drug_002_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.418086223
#> 92: G00003_drug_003_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.203645096
#> 93: G00004_drug_004_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.132168662
#> 94: G00005_drug_005_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.024941265
#> 95: G00006_drug_006_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.249504542
#> 96: G00007_drug_007_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.176988967
#> 97: G00008_drug_008_moa_A_72 CL00020_cellline_KB_tissue_z_62 -0.264481101
#> 98: G00009_drug_009_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.077484203
#> 99: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.199150357
#> 100: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 -0.114813416
#> r Id c Id GR Mean
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> <num> <num> <num> <num> <num>
#> 1: 0.52707024 0.60484720 0.008956223 0.33660000 0.004512560
#> 2: 0.60678014 0.70277140 0.006591468 0.25136667 0.004714084
#> 3: 0.16067286 0.19050089 Inf 0.76383333 0.017152797
#> 4: 0.21829189 0.25018175 Inf 0.73936667 0.003425139
#> 5: 0.35324082 0.41393595 Inf 0.56643333 0.004372707
#> 6: 0.06256320 0.06575521 Inf 0.89593333 6.055622159
#> 7: 0.27945710 0.30997686 Inf 0.65743333 0.002559558
#> 8: 0.29515042 0.34870740 Inf 0.63046667 0.008778928
#> 9: 0.13918583 0.16273320 Inf 0.77656667 0.032779888
#> 10: 0.79284054 0.93195933 0.021403060 -0.24116667 0.025129204
#> 11: 0.28981048 0.33967455 Inf 0.65893333 0.005025942
#> 12: 0.66725210 0.76169198 0.003994252 0.17163333 0.003302060
#> 13: 0.07790062 0.09343051 Inf 0.88726667 0.008287858
#> 14: 0.19169076 0.22105147 Inf 0.79443333 0.003408721
#> 15: 0.13309653 0.15708142 Inf 0.82726667 0.008098714
#> 16: 0.16301495 0.18647466 Inf 0.79136667 0.003969114
#> 17: 0.20856404 0.24449577 Inf 0.67090000 0.027533368
#> 18: 0.50868638 0.60551778 0.014718394 0.30453333 0.010370991
#> 19: 0.23625048 0.28073456 Inf 0.67690000 0.011214419
#> 20: 0.21934999 0.26078562 Inf 0.70800000 0.008628168
#> 21: 0.20575103 0.24291610 Inf 0.68636667 0.018792763
#> 22: 0.62517214 0.72107940 0.004733541 0.24863333 0.003733333
#> 23: 0.29083246 0.34315973 Inf 0.57196667 0.019154852
#> 24: 0.30289542 0.35827349 Inf 0.56803333 0.015397125
#> 25: 0.32312438 0.38472189 Inf 0.57023333 0.007742051
#> 26: 0.34758529 0.41267609 Inf 0.50863333 0.011835446
#> 27: 0.01561481 0.01561481 Inf 0.97146667 0.000000000
#> 28: 0.48556711 0.56936523 0.034901667 0.22980000 0.022820133
#> 29: 0.12151749 0.14271246 Inf 0.82306667 0.024473312
#> 30: 0.36528445 0.43067820 Inf 0.51870000 0.007550572
#> 31: 0.14198512 0.16878024 Inf 0.80660000 0.007501824
#> 32: 0.09040851 0.10536618 Inf 0.82636667 0.038864061
#> 33: 0.13576272 0.15824641 Inf 0.76243333 0.038650933
#> 34: 0.06070529 0.07176469 Inf 0.91113333 0.020890672
#> 35: 0.33089278 0.39183474 Inf 0.59120000 0.005647023
#> 36: 0.12389583 0.14638273 Inf 0.78433333 0.021030163
#> 37: 0.01256667 0.01256667 Inf 0.97186667 0.000000000
#> 38: 0.24726009 0.29120537 Inf 0.61536667 0.024975182
#> 39: 0.14267367 0.16980694 Inf 0.81726667 0.008782943
#> 40: 0.56412736 0.63987995 0.083979077 -0.09190000 0.092656739
#> 41: 0.71998220 0.84636750 0.007532111 0.06133333 0.006931018
#> 42: 0.46368468 0.54490372 0.011313171 0.42486667 0.005539077
#> 43: 0.90251955 1.05310942 0.004804846 -0.15033333 0.005196465
#> 44: 1.03839112 1.14486626 0.002096183 -0.21590000 0.002402173
#> 45: 0.19832688 0.23289841 Inf 0.72833333 0.007472182
#> 46: 0.54083649 0.63547037 0.019685244 0.20183333 0.013344832
#> 47: 0.73806860 0.84884751 0.004278853 0.10913333 0.003823207
#> 48: 0.30574963 0.35592969 Inf 0.62720000 0.004699445
#> 49: 0.19909147 0.23175051 Inf 0.71623333 0.013054619
#> 50: 1.28856146 1.52231622 0.006501568 -0.76076667 0.009877882
#> 51: 1.64550960 1.81869399 0.001554925 -0.88523333 0.002461726
#> 52: 1.15120962 1.36693104 0.011295294 -0.63760000 0.014964922
#> 53: 1.36240014 1.58088594 0.003102882 -0.64316667 0.003627803
#> 54: 1.32845474 1.52484992 0.002821583 -0.59106667 0.003261246
#> 55: 1.22480959 1.44589294 0.011797654 -0.85010000 0.018211003
#> 56: 1.26028100 1.40891804 0.002124075 -0.44813333 0.002908819
#> 57: 1.31414196 1.53378544 0.004126866 -0.66630000 0.006208157
#> 58: 1.18823069 1.39705508 0.011541663 -0.74830000 0.019093562
#> 59: 0.82253648 0.96378586 0.025291861 -0.34083333 0.030462173
#> 60: 0.50079720 0.59001656 0.009069128 0.39763333 0.005532738
#> 61: 0.94067036 1.10926395 0.017069264 -0.40870000 0.021770780
#> 62: 1.15676086 1.35220803 0.003518715 -0.43993333 0.003926883
#> 63: 1.21810732 1.44505824 0.007845694 -0.68250000 0.011080523
#> 64: 1.01798232 1.19375008 0.020839662 -0.55216667 0.028935636
#> 65: 0.73506165 0.87121078 0.012275930 -0.04430000 0.012435379
#> 66: 1.30503768 1.53138485 0.006343314 -0.74286667 0.010860272
#> 67: 1.21295497 1.41975706 0.005422182 -0.63310000 0.008331080
#> 68: 0.90801590 1.04589054 0.039209092 -0.66776667 0.057979675
#> 69: 0.91033138 1.05593041 0.005013879 -0.13980000 0.005644554
#> 70: 0.66567051 0.78831518 0.017651636 0.01416667 0.017187956
#> 71: 1.50140284 1.69282924 0.002079722 -0.75150000 0.003379462
#> 72: 0.92221903 1.08549021 0.008896978 -0.26123333 0.011083282
#> 73: 1.13176002 1.31651313 0.004407585 -0.40610000 0.006019440
#> 74: 1.09398883 1.29535998 0.006947625 -0.41440000 0.009103145
#> 75: 1.12573401 1.32679092 0.016745695 -0.69520000 0.023147806
#> 76: 0.99680982 1.14178852 0.003824450 -0.20206667 0.004653230
#> 77: 1.28615912 1.51385999 0.009229506 -0.88796667 0.015867486
#> 78: 0.88779863 1.02895436 0.028449345 -0.53723333 0.043025854
#> 79: 1.00598048 1.16593241 0.034588147 -0.76266667 0.047602705
#> 80: 0.73295675 0.85892056 0.023671502 -0.19190000 0.026969054
#> 81: 0.39317207 0.46194732 0.053626857 0.41883333 0.019690231
#> 82: 0.36948898 0.42607970 0.087295888 0.31943333 0.056703027
#> 83: 0.51602601 0.57087256 0.143455577 -0.22873333 0.167033674
#> 84: 0.41879600 0.45743157 0.212648132 -0.02213333 0.212600715
#> 85: 0.26848103 0.30032538 0.344685074 0.42540000 0.131446499
#> 86: 0.36038724 0.40984406 0.117452572 0.26290000 0.086914958
#> 87: 0.22582416 0.25108633 Inf 0.48070000 0.150506549
#> 88: 0.40421325 0.45641866 0.126923290 0.18620000 0.104938005
#> 89: 0.25561534 0.27576952 0.482004214 0.34280000 0.262050505
#> 90: 0.55024130 0.61304737 0.120388567 -0.23676667 0.143651843
#> 91: 0.58191378 0.68366685 0.017638803 0.15233333 0.013459091
#> 92: 0.79635490 0.91959952 0.039776880 -0.45710000 0.052972634
#> 93: 1.13216866 1.33323831 0.006256750 -0.47600000 0.008730800
#> 94: 1.02494127 1.20800058 0.016682174 -0.54256667 0.022466542
#> 95: 0.75049546 0.85590610 0.058794620 -0.48653333 0.079484138
#> 96: 0.82301103 0.96481060 0.025824025 -0.31900000 0.030306953
#> 97: 1.26448110 1.49594653 0.008219032 -0.77343333 0.012547541
#> 98: 0.92251580 1.07425601 0.026077313 -0.49686667 0.037516853
#> 99: 0.80084964 0.89159948 0.096729600 -0.78626667 0.146270629
#> 100: 1.11481342 1.30596053 0.016239553 -0.76026667 0.026434030
#> GR AOC GR AOC within set range GR50 GR Max GEC50
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> <num> <num> <num> <num> <num> <num>
#> 1: 0.3651678148 1.0000000 1.9119007 0.9884406 1.660656e-07 0.0045303452
#> 2: 0.2663967900 1.0000000 2.2700932 0.9905292 8.267143e-08 0.0056700663
#> 3: 0.7669777183 1.0000000 3.1437068 0.9914280 5.831599e-08 0.0007996589
#> 4: 0.7468373651 1.0000000 3.3444924 0.9757902 2.207855e-06 0.0014589160
#> 5: 0.5776422640 1.0000000 3.7583023 0.9968734 1.709038e-09 0.0006971243
#> 6: 0.7767392076 1.0000000 0.2541701 0.7382169 9.179004e-03 0.0039751137
#> 7: 0.6856295469 1.0000000 2.2283677 0.9732050 3.149112e-06 0.0020708650
#> 8: 0.6122474630 1.0000000 2.2285708 0.9880579 1.861139e-07 0.0024924890
#> 9: 0.7754650425 1.0000000 2.2889985 0.9888129 1.480842e-07 0.0009916378
#> 10: -0.2226798163 1.0000000 2.2951127 0.9990488 2.654224e-11 0.0024404603
#> 11: 0.6470730550 1.0000000 2.8677996 0.9704197 4.451549e-06 0.0049211098
#> 12: 0.2295353843 1.0000000 3.2287691 0.9908815 7.239884e-08 0.0055504640
#> 13: 0.8985288362 1.0000000 5.0000000 0.8578698 1.082436e-03 0.0017311323
#> 14: 0.7779257424 1.0000000 5.0000000 0.9811907 9.126541e-07 0.0009519863
#> 15: 0.8271028214 1.0000000 2.2446169 0.9693003 5.069529e-06 0.0012425224
#> 16: 0.8069689420 1.0000000 2.1324423 0.9532749 2.205084e-05 0.0019540733
#> 17: 0.6734026973 1.0000000 2.0561031 0.9962473 3.237437e-09 0.0006692208
#> 18: 0.3158838755 1.0000000 2.8537073 0.9979296 4.037965e-10 0.0014073691
#> 19: 0.6786316274 1.0000000 2.6189994 0.9900052 9.981764e-08 0.0015756760
#> 20: 0.7126300563 1.0000000 2.7803450 0.9884951 1.633382e-07 0.0014199653
#> 21: 0.6972688823 1.0000000 2.2630422 0.9939342 1.738238e-08 0.0009119932
#> 22: 0.2671164396 1.0000000 3.2188686 0.9942855 1.410692e-08 0.0033809061
#> 23: 0.5707831317 1.0000000 2.2058511 0.9885236 1.619263e-07 0.0035039079
#> 24: 0.5679295931 1.0000000 2.2341289 0.9974080 8.865540e-10 0.0007253857
#> 25: 0.5830557926 1.0000000 3.0941181 0.9915566 5.531131e-08 0.0020546400
#> 26: 0.5234219383 1.0000000 2.5223390 0.9945689 1.180644e-08 0.0018728900
#> 27: 0.9843851852 0.9843852 0.0001000 0.0000000 5.051366e-01 0.0026667731
#> 28: 0.2627284849 1.0000000 1.7543375 0.9929829 2.894338e-08 0.0058346518
#> 29: 0.8134059397 1.0000000 2.0261477 0.9701477 4.596431e-06 0.0017203009
#> 30: 0.5300584965 1.0000000 2.2706141 0.9915850 5.466156e-08 0.0025042007
#> 31: 0.8175800194 1.0000000 2.9545779 0.9263136 1.086067e-04 0.0047546911
#> 32: 0.8497191486 1.0000000 5.0000000 0.9414806 4.847844e-05 0.0028277725
#> 33: 0.7745509842 1.0000000 5.0000000 0.9905919 8.077212e-08 0.0009703665
#> 34: 0.9091685072 1.0000000 5.0000000 0.8703307 7.851092e-04 0.0036147863
#> 35: 0.5909223718 1.0000000 3.3653065 0.9965291 2.463576e-09 0.0007708945
#> 36: 0.8144193534 1.0000000 3.2484642 0.9602404 1.253272e-05 0.0023079249
#> 37: 0.9874333333 0.9874333 0.0001000 0.0000000 5.226792e-01 0.0045005377
#> 38: 0.6190909106 1.0000000 5.0000000 0.9916347 5.354032e-08 0.0021490509
#> 39: 0.8126203033 1.0000000 2.8923837 0.9340415 7.369655e-05 0.0030096935
#> 40: -0.1100555561 1.0000000 2.0231247 0.9954539 6.335023e-09 0.0101608866
#> 41: 0.0843948493 1.0000000 2.2228625 0.9989540 3.700785e-11 0.0011299281
#> 42: 0.4280422001 1.0000000 2.7144943 0.9939185 1.754023e-08 0.0025486690
#> 43: -0.1044494537 1.0000000 2.4212065 0.9902549 9.135969e-08 0.0134618257
#> 44: -0.1620560072 1.0000000 2.0604060 0.9892455 1.289925e-07 0.0102617483
#> 45: 0.7451155399 1.0000000 2.0612207 0.9805388 1.028230e-06 0.0016676158
#> 46: 0.2444903289 1.0000000 1.7269837 0.9955545 5.857477e-09 0.0035994749
#> 47: 0.1316629628 1.0000000 2.7142277 0.9946978 1.085451e-08 0.0041780160
#> 48: 0.6307693263 1.0000000 2.6162346 0.9927082 3.310784e-08 0.0012196886
#> 49: 0.7222776333 1.0000000 1.3911231 0.9644174 8.498288e-06 0.0035483729
#> 50: -0.7215144153 1.0000000 2.1356334 0.9986787 8.385582e-11 0.0054197260
#> 51: -0.8445230124 1.0000000 2.1530486 0.9970059 1.468626e-09 0.0074471434
#> 52: -0.6348290617 1.0000000 2.9134838 0.9975549 7.227836e-10 0.0105548724
#> 53: -0.5906663271 1.0000000 4.9901264 0.9835173 5.749117e-07 0.0479741017
#> 54: -0.5306044465 1.0000000 4.9947313 0.9909207 7.131558e-08 0.0204750192
#> 55: -0.7932565672 1.0000000 2.1890242 0.9987491 6.923104e-11 0.0064150301
#> 56: -0.4405596014 1.0000000 2.0096850 0.9868501 2.607523e-07 0.0214141959
#> 57: -0.6475910270 1.0000000 2.0345801 0.9915706 5.499090e-08 0.0270484156
#> 58: -0.7531963509 1.0000000 1.8253213 0.9987855 6.243166e-11 0.0057202466
#> 59: -0.3102371436 1.0000000 2.5952204 0.9989539 3.702390e-11 0.0032347548
#> 60: 0.3824493623 1.0000000 2.9294992 0.9857446 3.458839e-07 0.0066776424
#> 61: -0.4169392990 1.0000000 2.4926426 0.9974568 8.294838e-10 0.0090820977
#> 62: -0.3641218697 1.0000000 4.9850173 0.9908614 7.295866e-08 0.0208479700
#> 63: -0.6541862131 1.0000000 2.4231874 0.9914850 5.697009e-08 0.0358041319
#> 64: -0.6074320061 1.0000000 2.4227680 0.9960819 3.765019e-09 0.0174257673
#> 65: -0.0153061841 1.0000000 2.3365273 0.9964806 2.586138e-09 0.0056269403
#> 66: -0.7689648974 1.0000000 1.7320650 0.9970436 1.404914e-09 0.0123458770
#> 67: -0.5835770177 1.0000000 1.8007551 0.9976480 6.309898e-10 0.0073846724
#> 68: -0.6255619766 1.0000000 2.0742923 0.9975373 7.412210e-10 0.0119795999
#> 69: -0.1277776181 1.0000000 1.9207939 0.9938926 1.780359e-08 0.0087658850
#> 70: 0.0342563614 1.0000000 2.6661846 0.9973400 9.707612e-10 0.0042664707
#> 71: -0.7476426517 1.0000000 1.8834936 0.9984594 1.435180e-10 0.0039640590
#> 72: -0.2532259879 1.0000000 1.8648542 0.9995596 1.792360e-12 0.0009511982
#> 73: -0.4137519625 1.0000000 1.9345991 0.9993732 6.163698e-12 0.0014555916
#> 74: -0.4443998175 1.0000000 2.3534208 0.9951423 7.989316e-09 0.0137384037
#> 75: -0.7126817181 1.0000000 2.7365478 0.9986032 1.018578e-10 0.0071007044
#> 76: -0.2065860191 1.0000000 1.7631520 0.9967875 1.879027e-09 0.0045316079
#> 77: -0.8438328827 1.0000000 1.8245692 0.9973253 9.896588e-10 0.0137058624
#> 78: -0.5033105133 1.0000000 1.6835691 0.9980112 3.507995e-10 0.0074336916
#> 79: -0.7350666349 1.0000000 2.8313491 0.9990251 2.892854e-11 0.0055864178
#> 80: -0.1438326892 1.0000000 1.9386164 0.9958942 4.434905e-09 0.0087060442
#> 81: 0.4170287342 1.0000000 1.7926586 0.9981406 2.772138e-10 0.0009814830
#> 82: 0.3413600699 1.0000000 2.6605690 0.9970120 1.458224e-09 0.0025565632
#> 83: -0.1599302533 1.0000000 1.8237894 0.9955606 5.829534e-09 0.0104168368
#> 84: 0.0002979208 1.0000000 2.6726325 0.9985093 1.279117e-10 0.0027912514
#> 85: 0.4295060402 1.0000000 2.0321759 0.9950986 8.243686e-09 0.0029000027
#> 86: 0.3003216477 1.0000000 3.0484446 0.9946346 1.131362e-08 0.0051502481
#> 87: 0.5048265847 1.0000000 3.5683198 0.9917107 5.185758e-08 0.0042469987
#> 88: 0.1831084883 1.0000000 2.3975662 0.9924392 3.758273e-08 0.0100206531
#> 89: 0.3552684841 1.0000000 2.0342894 0.9950033 8.818716e-09 0.0038048777
#> 90: -0.1933830016 1.0000000 1.8507842 0.9967431 1.971582e-09 0.0085515416
#> 91: 0.1860626932 1.0000000 1.7209131 0.9966220 2.240260e-09 0.0032422970
#> 92: -0.4013139858 1.0000000 2.0567782 0.9965388 2.439530e-09 0.0120338036
#> 93: -0.4866785556 1.0000000 2.0400478 0.9952028 7.646630e-09 0.0143425595
#> 94: -0.5517780648 1.0000000 2.4980285 0.9985723 1.099614e-10 0.0059898596
#> 95: -0.4303883285 1.0000000 2.0596328 0.9969133 1.633858e-09 0.0120169616
#> 96: -0.3098387168 1.0000000 3.0125648 0.9977677 5.256069e-10 0.0074113065
#> 97: -0.7490788673 1.0000000 2.1640592 0.9987682 6.560411e-11 0.0055870262
#> 98: -0.5239352601 1.0000000 1.9707233 0.9955609 5.828304e-09 0.0174009206
#> 99: -0.7443040083 1.0000000 2.2046853 0.9985705 1.104466e-10 0.0081610637
#> 100: -0.7340189608 1.0000000 1.8543083 0.9987249 7.403286e-11 0.0064842414
#> GR Inf GR 0 h GR GR R2 GR p Value GR Rss
#> GR Sd Avg Fit Type GR GR maxlog10Concentration GR N Conc
#> <num> <char> <num> <int>
#> 1: 0.03203268 DRC3pHillFitModelFixS0 1 9
#> 2: 0.03075240 DRC3pHillFitModelFixS0 1 9
#> 3: 0.02000573 DRC3pHillFitModelFixS0 1 9
#> 4: 0.02214360 DRC3pHillFitModelFixS0 1 9
#> 5: 0.03066180 DRC3pHillFitModelFixS0 1 9
#> 6: 0.02346065 DRC3pHillFitModelFixS0 1 9
#> 7: 0.02679197 DRC3pHillFitModelFixS0 1 9
#> 8: 0.01983125 DRC3pHillFitModelFixS0 1 9
#> 9: 0.01910174 DRC3pHillFitModelFixS0 1 9
#> 10: 0.07130873 DRC3pHillFitModelFixS0 1 9
#> 11: 0.02101516 DRC3pHillFitModelFixS0 1 9
#> 12: 0.03850179 DRC3pHillFitModelFixS0 1 9
#> 13: 0.03205436 DRC3pHillFitModelFixS0 1 9
#> 14: 0.02326291 DRC3pHillFitModelFixS0 1 9
#> 15: 0.02352653 DRC3pHillFitModelFixS0 1 9
#> 16: 0.02344649 DRC3pHillFitModelFixS0 1 9
#> 17: 0.03340578 DRC3pHillFitModelFixS0 1 9
#> 18: 0.03448935 DRC3pHillFitModelFixS0 1 9
#> 19: 0.02377445 DRC3pHillFitModelFixS0 1 9
#> 20: 0.02630609 DRC3pHillFitModelFixS0 1 9
#> 21: 0.02570997 DRC3pHillFitModelFixS0 1 9
#> 22: 0.03926750 DRC3pHillFitModelFixS0 1 9
#> 23: 0.02824974 DRC3pHillFitModelFixS0 1 9
#> 24: 0.02856021 DRC3pHillFitModelFixS0 1 9
#> 25: 0.02557931 DRC3pHillFitModelFixS0 1 9
#> 26: 0.02875531 DRC3pHillFitModelFixS0 1 9
#> 27: 0.02503984 DRCConstantFitResult 1 9
#> 28: 0.03690901 DRC3pHillFitModelFixS0 1 9
#> 29: 0.02418509 DRC3pHillFitModelFixS0 1 9
#> 30: 0.02944348 DRC3pHillFitModelFixS0 1 9
#> 31: 0.02872952 DRC3pHillFitModelFixS0 1 9
#> 32: 0.03452733 DRC3pHillFitModelFixS0 1 9
#> 33: 0.03283285 DRC3pHillFitModelFixS0 1 9
#> 34: 0.02600261 DRC3pHillFitModelFixS0 1 9
#> 35: 0.02690396 DRC3pHillFitModelFixS0 1 9
#> 36: 0.03016809 DRC3pHillFitModelFixS0 1 9
#> 37: 0.02836629 DRCConstantFitResult 1 9
#> 38: 0.02649059 DRC3pHillFitModelFixS0 1 9
#> 39: 0.02525543 DRC3pHillFitModelFixS0 1 9
#> 40: 0.05432540 DRC3pHillFitModelFixS0 1 9
#> 41: 0.04268871 DRC3pHillFitModelFixS0 1 9
#> 42: 0.03167032 DRC3pHillFitModelFixS0 1 9
#> 43: 0.04581144 DRC3pHillFitModelFixS0 1 9
#> 44: 0.04712220 DRC3pHillFitModelFixS0 1 9
#> 45: 0.03663539 DRC3pHillFitModelFixS0 1 9
#> 46: 0.04114510 DRC3pHillFitModelFixS0 1 9
#> 47: 0.02957059 DRC3pHillFitModelFixS0 1 9
#> 48: 0.04836989 DRC3pHillFitModelFixS0 1 9
#> 49: 0.01995472 DRC3pHillFitModelFixS0 1 9
#> 50: 0.09569389 DRC3pHillFitModelFixS0 1 9
#> 51: 0.05883646 DRC3pHillFitModelFixS0 1 9
#> 52: 0.05621152 DRC3pHillFitModelFixS0 1 9
#> 53: 0.06787391 DRC3pHillFitModelFixS0 1 9
#> 54: 0.06158907 DRC3pHillFitModelFixS0 1 9
#> 55: 0.07877147 DRC3pHillFitModelFixS0 1 9
#> 56: 0.06417974 DRC3pHillFitModelFixS0 1 9
#> 57: 0.06360624 DRC3pHillFitModelFixS0 1 9
#> 58: 0.08699730 DRC3pHillFitModelFixS0 1 9
#> 59: 0.03924611 DRC3pHillFitModelFixS0 1 9
#> 60: 0.02995868 DRC3pHillFitModelFixS0 1 9
#> 61: 0.04815310 DRC3pHillFitModelFixS0 1 9
#> 62: 0.05756475 DRC3pHillFitModelFixS0 1 9
#> 63: 0.05772902 DRC3pHillFitModelFixS0 1 9
#> 64: 0.05544735 DRC3pHillFitModelFixS0 1 9
#> 65: 0.04812444 DRC3pHillFitModelFixS0 1 9
#> 66: 0.10139524 DRC3pHillFitModelFixS0 1 9
#> 67: 0.06146191 DRC3pHillFitModelFixS0 1 9
#> 68: 0.05594040 DRC3pHillFitModelFixS0 1 9
#> 69: 0.04122973 DRC3pHillFitModelFixS0 1 9
#> 70: 0.03674990 DRC3pHillFitModelFixS0 1 9
#> 71: 0.07586112 DRC3pHillFitModelFixS0 1 9
#> 72: 0.04007412 DRC3pHillFitModelFixS0 1 9
#> 73: 0.06975153 DRC3pHillFitModelFixS0 1 9
#> 74: 0.03442655 DRC3pHillFitModelFixS0 1 9
#> 75: 0.06771926 DRC3pHillFitModelFixS0 1 9
#> 76: 0.04856655 DRC3pHillFitModelFixS0 1 9
#> 77: 0.06455336 DRC3pHillFitModelFixS0 1 9
#> 78: 0.06514096 DRC3pHillFitModelFixS0 1 9
#> 79: 0.04920195 DRC3pHillFitModelFixS0 1 9
#> 80: 0.05402095 DRC3pHillFitModelFixS0 1 9
#> 81: 0.04906576 DRC3pHillFitModelFixS0 1 9
#> 82: 0.04751873 DRC3pHillFitModelFixS0 1 9
#> 83: 0.04074026 DRC3pHillFitModelFixS0 1 9
#> 84: 0.05740278 DRC3pHillFitModelFixS0 1 9
#> 85: 0.04942568 DRC3pHillFitModelFixS0 1 9
#> 86: 0.04407493 DRC3pHillFitModelFixS0 1 9
#> 87: 0.05235831 DRC3pHillFitModelFixS0 1 9
#> 88: 0.04841497 DRC3pHillFitModelFixS0 1 9
#> 89: 0.05300916 DRC3pHillFitModelFixS0 1 9
#> 90: 0.03421832 DRC3pHillFitModelFixS0 1 9
#> 91: 0.04289095 DRC3pHillFitModelFixS0 1 9
#> 92: 0.05008110 DRC3pHillFitModelFixS0 1 9
#> 93: 0.04267612 DRC3pHillFitModelFixS0 1 9
#> 94: 0.06048658 DRC3pHillFitModelFixS0 1 9
#> 95: 0.05057676 DRC3pHillFitModelFixS0 1 9
#> 96: 0.03418831 DRC3pHillFitModelFixS0 1 9
#> 97: 0.04674118 DRC3pHillFitModelFixS0 1 9
#> 98: 0.04602459 DRC3pHillFitModelFixS0 1 9
#> 99: 0.06333498 DRC3pHillFitModelFixS0 1 9
#> 100: 0.07007818 DRC3pHillFitModelFixS0 1 9
#> GR Sd Avg Fit Type GR GR maxlog10Concentration GR N Conc
#> Fit Source Gnumber Drug Name Drug MOA Duration Clid Cell Line Name
#> <char> <char> <char> <char> <num> <char> <char>
#> 1: gDR G00002 drug_002 moa_A 72 CL00011 cellline_BA
#> 2: gDR G00003 drug_003 moa_A 72 CL00011 cellline_BA
#> 3: gDR G00004 drug_004 moa_A 72 CL00011 cellline_BA
#> 4: gDR G00005 drug_005 moa_A 72 CL00011 cellline_BA
#> 5: gDR G00006 drug_006 moa_A 72 CL00011 cellline_BA
#> 6: gDR G00007 drug_007 moa_A 72 CL00011 cellline_BA
#> 7: gDR G00008 drug_008 moa_A 72 CL00011 cellline_BA
#> 8: gDR G00009 drug_009 moa_A 72 CL00011 cellline_BA
#> 9: gDR G00010 drug_010 moa_A 72 CL00011 cellline_BA
#> 10: gDR G00011 drug_011 moa_B 72 CL00011 cellline_BA
#> 11: gDR G00002 drug_002 moa_A 72 CL00012 cellline_CA
#> 12: gDR G00003 drug_003 moa_A 72 CL00012 cellline_CA
#> 13: gDR G00004 drug_004 moa_A 72 CL00012 cellline_CA
#> 14: gDR G00005 drug_005 moa_A 72 CL00012 cellline_CA
#> 15: gDR G00006 drug_006 moa_A 72 CL00012 cellline_CA
#> 16: gDR G00007 drug_007 moa_A 72 CL00012 cellline_CA
#> 17: gDR G00008 drug_008 moa_A 72 CL00012 cellline_CA
#> 18: gDR G00009 drug_009 moa_A 72 CL00012 cellline_CA
#> 19: gDR G00010 drug_010 moa_A 72 CL00012 cellline_CA
#> 20: gDR G00011 drug_011 moa_B 72 CL00012 cellline_CA
#> 21: gDR G00002 drug_002 moa_A 72 CL00013 cellline_DA
#> 22: gDR G00003 drug_003 moa_A 72 CL00013 cellline_DA
#> 23: gDR G00004 drug_004 moa_A 72 CL00013 cellline_DA
#> 24: gDR G00005 drug_005 moa_A 72 CL00013 cellline_DA
#> 25: gDR G00006 drug_006 moa_A 72 CL00013 cellline_DA
#> 26: gDR G00007 drug_007 moa_A 72 CL00013 cellline_DA
#> 27: gDR G00008 drug_008 moa_A 72 CL00013 cellline_DA
#> 28: gDR G00009 drug_009 moa_A 72 CL00013 cellline_DA
#> 29: gDR G00010 drug_010 moa_A 72 CL00013 cellline_DA
#> 30: gDR G00011 drug_011 moa_B 72 CL00013 cellline_DA
#> 31: gDR G00002 drug_002 moa_A 72 CL00014 cellline_EA
#> 32: gDR G00003 drug_003 moa_A 72 CL00014 cellline_EA
#> 33: gDR G00004 drug_004 moa_A 72 CL00014 cellline_EA
#> 34: gDR G00005 drug_005 moa_A 72 CL00014 cellline_EA
#> 35: gDR G00006 drug_006 moa_A 72 CL00014 cellline_EA
#> 36: gDR G00007 drug_007 moa_A 72 CL00014 cellline_EA
#> 37: gDR G00008 drug_008 moa_A 72 CL00014 cellline_EA
#> 38: gDR G00009 drug_009 moa_A 72 CL00014 cellline_EA
#> 39: gDR G00010 drug_010 moa_A 72 CL00014 cellline_EA
#> 40: gDR G00011 drug_011 moa_B 72 CL00014 cellline_EA
#> 41: gDR G00002 drug_002 moa_A 72 CL00015 cellline_FA
#> 42: gDR G00003 drug_003 moa_A 72 CL00015 cellline_FA
#> 43: gDR G00004 drug_004 moa_A 72 CL00015 cellline_FA
#> 44: gDR G00005 drug_005 moa_A 72 CL00015 cellline_FA
#> 45: gDR G00006 drug_006 moa_A 72 CL00015 cellline_FA
#> 46: gDR G00007 drug_007 moa_A 72 CL00015 cellline_FA
#> 47: gDR G00008 drug_008 moa_A 72 CL00015 cellline_FA
#> 48: gDR G00009 drug_009 moa_A 72 CL00015 cellline_FA
#> 49: gDR G00010 drug_010 moa_A 72 CL00015 cellline_FA
#> 50: gDR G00011 drug_011 moa_B 72 CL00015 cellline_FA
#> 51: gDR G00002 drug_002 moa_A 72 CL00016 cellline_GB
#> 52: gDR G00003 drug_003 moa_A 72 CL00016 cellline_GB
#> 53: gDR G00004 drug_004 moa_A 72 CL00016 cellline_GB
#> 54: gDR G00005 drug_005 moa_A 72 CL00016 cellline_GB
#> 55: gDR G00006 drug_006 moa_A 72 CL00016 cellline_GB
#> 56: gDR G00007 drug_007 moa_A 72 CL00016 cellline_GB
#> 57: gDR G00008 drug_008 moa_A 72 CL00016 cellline_GB
#> 58: gDR G00009 drug_009 moa_A 72 CL00016 cellline_GB
#> 59: gDR G00010 drug_010 moa_A 72 CL00016 cellline_GB
#> 60: gDR G00011 drug_011 moa_B 72 CL00016 cellline_GB
#> 61: gDR G00002 drug_002 moa_A 72 CL00017 cellline_HB
#> 62: gDR G00003 drug_003 moa_A 72 CL00017 cellline_HB
#> 63: gDR G00004 drug_004 moa_A 72 CL00017 cellline_HB
#> 64: gDR G00005 drug_005 moa_A 72 CL00017 cellline_HB
#> 65: gDR G00006 drug_006 moa_A 72 CL00017 cellline_HB
#> 66: gDR G00007 drug_007 moa_A 72 CL00017 cellline_HB
#> 67: gDR G00008 drug_008 moa_A 72 CL00017 cellline_HB
#> 68: gDR G00009 drug_009 moa_A 72 CL00017 cellline_HB
#> 69: gDR G00010 drug_010 moa_A 72 CL00017 cellline_HB
#> 70: gDR G00011 drug_011 moa_B 72 CL00017 cellline_HB
#> 71: gDR G00002 drug_002 moa_A 72 CL00018 cellline_IB
#> 72: gDR G00003 drug_003 moa_A 72 CL00018 cellline_IB
#> 73: gDR G00004 drug_004 moa_A 72 CL00018 cellline_IB
#> 74: gDR G00005 drug_005 moa_A 72 CL00018 cellline_IB
#> 75: gDR G00006 drug_006 moa_A 72 CL00018 cellline_IB
#> 76: gDR G00007 drug_007 moa_A 72 CL00018 cellline_IB
#> 77: gDR G00008 drug_008 moa_A 72 CL00018 cellline_IB
#> 78: gDR G00009 drug_009 moa_A 72 CL00018 cellline_IB
#> 79: gDR G00010 drug_010 moa_A 72 CL00018 cellline_IB
#> 80: gDR G00011 drug_011 moa_B 72 CL00018 cellline_IB
#> 81: gDR G00002 drug_002 moa_A 72 CL00019 cellline_JB
#> 82: gDR G00003 drug_003 moa_A 72 CL00019 cellline_JB
#> 83: gDR G00004 drug_004 moa_A 72 CL00019 cellline_JB
#> 84: gDR G00005 drug_005 moa_A 72 CL00019 cellline_JB
#> 85: gDR G00006 drug_006 moa_A 72 CL00019 cellline_JB
#> 86: gDR G00007 drug_007 moa_A 72 CL00019 cellline_JB
#> 87: gDR G00008 drug_008 moa_A 72 CL00019 cellline_JB
#> 88: gDR G00009 drug_009 moa_A 72 CL00019 cellline_JB
#> 89: gDR G00010 drug_010 moa_A 72 CL00019 cellline_JB
#> 90: gDR G00011 drug_011 moa_B 72 CL00019 cellline_JB
#> 91: gDR G00002 drug_002 moa_A 72 CL00020 cellline_KB
#> 92: gDR G00003 drug_003 moa_A 72 CL00020 cellline_KB
#> 93: gDR G00004 drug_004 moa_A 72 CL00020 cellline_KB
#> 94: gDR G00005 drug_005 moa_A 72 CL00020 cellline_KB
#> 95: gDR G00006 drug_006 moa_A 72 CL00020 cellline_KB
#> 96: gDR G00007 drug_007 moa_A 72 CL00020 cellline_KB
#> 97: gDR G00008 drug_008 moa_A 72 CL00020 cellline_KB
#> 98: gDR G00009 drug_009 moa_A 72 CL00020 cellline_KB
#> 99: gDR G00010 drug_010 moa_A 72 CL00020 cellline_KB
#> 100: gDR G00011 drug_011 moa_B 72 CL00020 cellline_KB
#> Fit Source Gnumber Drug Name Drug MOA Duration Clid Cell Line Name
#> Tissue Reference Division Time RV Mean RV AOC
#> <char> <num> <num> <num>
#> 1: tissue_x 26 0.4466890 0.55331098
#> 2: tissue_x 26 0.3939872 0.60601279
#> 3: tissue_x 26 0.7989283 0.20107172
#> 4: tissue_x 26 0.7292519 0.27074809
#> 5: tissue_x 26 0.5948205 0.40517951
#> 6: tissue_x 26 0.9153135 0.08468651
#> 7: tissue_x 26 0.6627378 0.33726218
#> 8: tissue_x 26 0.6541186 0.34588137
#> 9: tissue_x 26 0.8247285 0.17527151
#> 10: tissue_x 26 0.3682302 0.63176984
#> 11: tissue_x 30 0.6926178 0.30738217
#> 12: tissue_x 30 0.3979780 0.60202205
#> 13: tissue_x 30 0.9100259 0.08997415
#> 14: tissue_x 30 0.7873037 0.21269633
#> 15: tissue_x 30 0.8494189 0.15058108
#> 16: tissue_x 30 0.8169558 0.18304416
#> 17: tissue_x 30 0.7755540 0.22444601
#> 18: tissue_x 30 0.5212853 0.47871472
#> 19: tissue_x 30 0.7463491 0.25365094
#> 20: tissue_x 30 0.7616189 0.23838111
#> 21: tissue_x 34 0.7992747 0.20072525
#> 22: tissue_x 34 0.4668574 0.53314262
#> 23: tissue_x 34 0.7261649 0.27383514
#> 24: tissue_x 34 0.7151504 0.28484957
#> 25: tissue_x 34 0.6956589 0.30434108
#> 26: tissue_x 34 0.6779461 0.32205391
#> 27: tissue_x 34 0.9838111 0.01618889
#> 28: tissue_x 34 0.5806643 0.41933574
#> 29: tissue_x 34 0.8776200 0.12238003
#> 30: tissue_x 34 0.6609849 0.33901514
#> 31: tissue_x 38 0.8710149 0.12898507
#> 32: tissue_x 38 0.9173053 0.08269470
#> 33: tissue_x 38 0.8778150 0.12218503
#> 34: tissue_x 38 0.9437698 0.05623016
#> 35: tissue_x 38 0.7144618 0.28553821
#> 36: tissue_x 38 0.8874428 0.11255721
#> 37: tissue_x 38 0.9883815 0.01161852
#> 38: tissue_x 38 0.7852841 0.21471593
#> 39: tissue_x 38 0.8700763 0.12992370
#> 40: tissue_x 38 0.5865688 0.41343121
#> 41: tissue_x 42 0.4828015 0.51719847
#> 42: tissue_x 42 0.6425053 0.35749468
#> 43: tissue_x 42 0.3805017 0.61949830
#> 44: tissue_x 42 0.2977827 0.70221726
#> 45: tissue_x 42 0.8375294 0.16247062
#> 46: tissue_x 42 0.5962853 0.40371474
#> 47: tissue_x 42 0.4657079 0.53429209
#> 48: tissue_x 42 0.7549529 0.24504707
#> 49: tissue_x 42 0.8372120 0.16278796
#> 50: tissue_x 42 0.2524798 0.74752018
#> 51: tissue_y 46 0.1021560 0.89784398
#> 52: tissue_y 46 0.3319590 0.66804098
#> 53: tissue_y 46 0.2102313 0.78976874
#> 54: tissue_y 46 0.2100452 0.78995479
#> 55: tissue_y 46 0.3146779 0.68532206
#> 56: tissue_y 46 0.2311182 0.76888180
#> 57: tissue_y 46 0.2364875 0.76351250
#> 58: tissue_y 46 0.3235937 0.67640628
#> 59: tissue_y 46 0.4821997 0.51780026
#> 60: tissue_y 46 0.6425491 0.35745090
#> 61: tissue_y 50 0.4403251 0.55967489
#> 62: tissue_y 50 0.3158261 0.68417394
#> 63: tissue_y 50 0.3117162 0.68828381
#> 64: tissue_y 50 0.4144975 0.58550254
#> 65: tissue_y 50 0.5330401 0.46695992
#> 66: tissue_y 50 0.2753604 0.72463961
#> 67: tissue_y 50 0.2988946 0.70110537
#> 68: tissue_y 50 0.4775211 0.52247889
#> 69: tissue_y 50 0.4307934 0.56920661
#> 70: tissue_y 50 0.5740133 0.42598675
#> 71: tissue_y 54 0.1817987 0.81820132
#> 72: tissue_y 54 0.4557736 0.54422640
#> 73: tissue_y 54 0.3473656 0.65263436
#> 74: tissue_y 54 0.3722520 0.62774797
#> 75: tissue_y 54 0.3820939 0.61790607
#> 76: tissue_y 54 0.4088002 0.59119981
#> 77: tissue_y 54 0.3086007 0.69139927
#> 78: tissue_y 54 0.4906996 0.50930040
#> 79: tissue_y 54 0.4496388 0.55036124
#> 80: tissue_y 54 0.5613320 0.43866803
#> 81: tissue_z 58 0.7645125 0.23548748
#> 82: tissue_z 58 0.7799746 0.22002537
#> 83: tissue_z 58 0.7029485 0.29705152
#> 84: tissue_z 58 0.7566058 0.24339421
#> 85: tissue_z 58 0.8388170 0.16118297
#> 86: tissue_z 58 0.7862239 0.21377605
#> 87: tissue_z 58 0.8640795 0.13592048
#> 88: tissue_z 58 0.7614460 0.23855403
#> 89: tissue_z 58 0.8471580 0.15284198
#> 90: tissue_z 58 0.6842658 0.31573420
#> 91: tissue_z 62 0.6737095 0.32629051
#> 92: tissue_z 62 0.5683750 0.43162499
#> 93: tissue_z 62 0.3916886 0.60831136
#> 94: tissue_z 62 0.4519141 0.54808592
#> 95: tissue_z 62 0.5938560 0.40614404
#> 96: tissue_z 62 0.5525910 0.44740898
#> 97: tissue_z 62 0.3356482 0.66435184
#> 98: tissue_z 62 0.5045079 0.49549211
#> 99: tissue_z 62 0.5769999 0.42300010
#> 100: tissue_z 62 0.4117805 0.58821946
#> Tissue Reference Division Time RV Mean RV AOC
#> RV AOC within set range IC50 E Max EC50 E Inf
#> <num> <num> <num> <num> <num>
#> 1: 0.62771204 0.007253171 0.32793333 0.003795893 0.34682665
#> 2: 0.69549935 0.005655581 0.27413333 0.003962986 0.28319787
#> 3: 0.23854321 Inf 0.70636667 0.016546380 0.71001484
#> 4: 0.30829556 Inf 0.67963333 0.003304929 0.68717703
#> 5: 0.47306641 Inf 0.50873333 0.004129702 0.51907021
#> 6: 0.09862965 Inf 0.86246667 0.023423073 0.87074092
#> 7: 0.37222482 Inf 0.59466667 0.002397623 0.62344087
#> 8: 0.40814181 Inf 0.56796667 0.008060179 0.55098117
#> 9: 0.20515620 Inf 0.72036667 0.031276165 0.71953596
#> 10: 0.74702096 0.019384886 0.07090000 0.018136158 0.07568110
#> 11: 0.35949454 Inf 0.63853333 0.004774753 0.62816339
#> 12: 0.68371983 0.003821711 0.27726667 0.003008201 0.31309370
#> 13: 0.10791352 Inf 0.87040000 0.008254080 0.88286917
#> 14: 0.24486763 Inf 0.77096667 0.003354506 0.75408088
#> 15: 0.17760851 Inf 0.80546667 0.007866347 0.80517426
#> 16: 0.20901519 Inf 0.76806667 0.003815689 0.78433529
#> 17: 0.26336442 Inf 0.64960000 0.025909149 0.65208728
#> 18: 0.56881144 0.015334114 0.35873333 0.009338353 0.36576263
#> 19: 0.30161904 Inf 0.65570000 0.010664967 0.65748115
#> 20: 0.28326524 Inf 0.68473333 0.008285395 0.68946503
#> 21: 0.23709408 Inf 0.69726667 0.018014759 0.70662235
#> 22: 0.61173591 0.005175017 0.36916667 0.003431788 0.38161495
#> 23: 0.32331797 Inf 0.60056667 0.017991972 0.59983667
#> 24: 0.33700199 Inf 0.59763333 0.014539308 0.59720052
#> 25: 0.36205275 Inf 0.59926667 0.007397397 0.60975201
#> 26: 0.38244556 Inf 0.55096667 0.011148175 0.56228258
#> 27: 0.01618889 Inf 0.97033333 0.000000000 0.98381111
#> 28: 0.49233133 0.044349772 0.35713333 0.019771994 0.37777983
#> 29: 0.14379727 Inf 0.82200000 0.023835769 0.81289660
#> 30: 0.39942016 Inf 0.55890000 0.007078033 0.56771316
#> 31: 0.15337431 Inf 0.82480000 0.007404640 0.83458186
#> 32: 0.09639032 Inf 0.84193333 0.038642612 0.86268158
#> 33: 0.14245939 Inf 0.78713333 0.038237333 0.79748718
#> 34: 0.06647635 Inf 0.91773333 0.020858876 0.91588511
#> 35: 0.33774750 Inf 0.64843333 0.005482997 0.64836791
#> 36: 0.13302031 Inf 0.80563333 0.020762148 0.83175068
#> 37: 0.01161852 Inf 0.97366667 0.000000000 0.98838148
#> 38: 0.25298214 Inf 0.66726667 0.024503188 0.67026768
#> 39: 0.15434173 Inf 0.83416667 0.008516796 0.83009341
#> 40: 0.47176921 0.103693590 0.22530000 0.077874576 0.21531639
#> 41: 0.60667873 0.010722078 0.33776667 0.006294304 0.35077573
#> 42: 0.41943708 Inf 0.55923333 0.005301487 0.56156486
#> 43: 0.71885082 0.006229871 0.23093333 0.004661971 0.25237654
#> 44: 0.76597220 0.002756447 0.20110000 0.002085738 0.22629021
#> 45: 0.19070324 Inf 0.77860000 0.007310403 0.79181981
#> 46: 0.47449665 0.041965155 0.41790000 0.012099942 0.44418366
#> 47: 0.61134861 0.005912214 0.36410000 0.003552790 0.37709397
#> 48: 0.28487547 Inf 0.70263333 0.004561251 0.70521133
#> 49: 0.18968302 Inf 0.76936667 0.012481407 0.77448135
#> 50: 0.88177300 0.007884476 0.02790000 0.007623490 0.03706278
#> 51: 0.97368081 0.001975139 0.01156667 0.001941693 0.02047816
#> 52: 0.79488065 0.013697468 0.06936667 0.013030558 0.07094849
#> 53: 0.90450614 0.003811979 0.06773333 0.003585337 0.07825779
#> 54: 0.88824111 0.003197359 0.08630000 0.002932087 0.09935284
#> 55: 0.81208812 0.014902515 0.01756667 0.014508564 0.03128655
#> 56: 0.84899908 0.002887489 0.13533333 0.002461805 0.13678567
#> 57: 0.88498708 0.005396956 0.06396667 0.005034691 0.06871316
#> 58: 0.79810483 0.015444308 0.04450000 0.014793650 0.04081369
#> 59: 0.60821155 0.032638339 0.17626667 0.027413659 0.18981432
#> 60: 0.42057145 Inf 0.57070000 0.005350482 0.56115445
#> 61: 0.66129430 0.023097263 0.17430000 0.019657332 0.17067228
#> 62: 0.79476913 0.004922621 0.16046667 0.004218802 0.18540041
#> 63: 0.81859408 0.010326282 0.07083333 0.009658844 0.08373933
#> 64: 0.68838500 0.027637201 0.11686667 0.025274379 0.09621464
#> 65: 0.55422115 0.019427772 0.34556667 0.011549019 0.36203554
#> 66: 0.84954049 0.009224850 0.05420000 0.008730319 0.04790721
#> 67: 0.81877562 0.007990484 0.08710000 0.007043304 0.10560283
#> 68: 0.60461228 0.054323446 0.07786667 0.049549089 0.09209706
#> 69: 0.65813446 0.008297512 0.29680000 0.005151240 0.30315714
#> 70: 0.50486302 0.028380166 0.37660000 0.016287291 0.38712847
#> 71: 0.91385902 0.003121891 0.06380000 0.002908151 0.06403699
#> 72: 0.64062126 0.015278400 0.26503333 0.010185821 0.26943207
#> 73: 0.75662897 0.007000949 0.19893333 0.005440592 0.19547452
#> 74: 0.74215883 0.010133991 0.19443333 0.008351180 0.18112340
#> 75: 0.72975315 0.022055538 0.08350000 0.020776435 0.07624990
#> 76: 0.67444555 0.007029613 0.29376667 0.004287339 0.29150899
#> 77: 0.81546273 0.013769074 0.02206667 0.013254560 0.03556904
#> 78: 0.59207687 0.047179141 0.14253333 0.037914493 0.15699796
#> 79: 0.63963532 0.045215408 0.05843333 0.043031281 0.06820615
#> 80: 0.51481053 0.042486343 0.29903333 0.025152816 0.32334398
#> 81: 0.27674936 Inf 0.65316667 0.019245011 0.65209837
#> 82: 0.25385986 Inf 0.59670000 0.055689068 0.60914083
#> 83: 0.32948401 0.295080096 0.30650000 0.158198620 0.34093110
#> 84: 0.26629466 0.413743153 0.41173333 0.206332658 0.42342449
#> 85: 0.18043264 Inf 0.65686667 0.129212028 0.65883941
#> 86: 0.24324624 Inf 0.56523333 0.085602158 0.58627595
#> 87: 0.15119347 Inf 0.68853333 0.149067206 0.70263542
#> 88: 0.26963522 Inf 0.52300000 0.102208367 0.52064083
#> 89: 0.16513000 Inf 0.61000000 0.256158972 0.61685311
#> 90: 0.35272441 0.236075692 0.30246667 0.135223132 0.32473738
#> 91: 0.38341599 Inf 0.52713333 0.013128583 0.54530841
#> 92: 0.49907540 0.070162438 0.22003333 0.050619652 0.24695917
#> 93: 0.71651338 0.010695136 0.21133333 0.008294007 0.20699055
#> 94: 0.64651950 0.025509994 0.18053333 0.021456873 0.17635164
#> 95: 0.46394440 0.102279380 0.20620000 0.075806992 0.23335970
#> 96: 0.52483930 0.039032319 0.28623333 0.029513143 0.29115866
#> 97: 0.78615325 0.012891906 0.08013333 0.011778656 0.08958619
#> 98: 0.57777110 0.045034344 0.20156667 0.035484367 0.18949638
#> 99: 0.47231044 0.150209032 0.07513333 0.137152296 0.09235428
#> 100: 0.69005808 0.027440547 0.08603333 0.024485958 0.09662172
#> RV AOC within set range IC50 E Max EC50 E Inf
#> E0 h RV RV R2 RV p Value RV Rss RV Sd Avg
#> <num> <num> <num> <num> <num> <num>
#> 1: 1.0000000 1.827031 0.9924695 3.705769e-08 0.0027788222 0.02424423
#> 2: 1.0000000 2.349599 0.9958511 4.600131e-09 0.0021823404 0.02195104
#> 3: 1.0000000 3.159939 0.9918874 4.809026e-08 0.0011623407 0.02315049
#> 4: 1.0000000 2.869796 0.9788260 1.381366e-06 0.0018580999 0.02433754
#> 5: 1.0000000 3.829228 0.9978624 4.515583e-10 0.0006002563 0.02914251
#> 6: 1.0000000 1.396984 0.9622053 1.049565e-05 0.0010089336 0.03095134
#> 7: 1.0000000 2.285910 0.9796018 1.212200e-06 0.0021497125 0.02851709
#> 8: 1.0000000 2.239456 0.9917851 5.024614e-08 0.0022433269 0.02120201
#> 9: 1.0000000 2.336379 0.9894868 1.191422e-07 0.0014484927 0.02368805
#> 10: 1.0000000 2.464822 0.9985658 1.117095e-10 0.0020514821 0.02467602
#> 11: 1.0000000 2.919115 0.9767620 1.912923e-06 0.0042266456 0.02026923
#> 12: 1.0000000 4.111036 0.9952426 7.426431e-09 0.0021879035 0.02564250
#> 13: 1.0000000 5.000000 0.8541039 1.186186e-03 0.0023608040 0.03624754
#> 14: 1.0000000 5.000000 0.9832682 6.059013e-07 0.0010166387 0.02462014
#> 15: 1.0000000 2.241526 0.9725466 3.428366e-06 0.0013962272 0.02581034
#> 16: 1.0000000 2.178830 0.9569420 1.656493e-05 0.0022229434 0.02491576
#> 17: 1.0000000 2.036162 0.9968137 1.825950e-09 0.0006398224 0.03482572
#> 18: 1.0000000 2.651473 0.9984890 1.340914e-10 0.0008475955 0.02606777
#> 19: 1.0000000 2.703715 0.9917990 4.995008e-08 0.0014512290 0.02352835
#> 20: 1.0000000 2.768447 0.9901512 9.480595e-08 0.0014125688 0.02706624
#> 21: 1.0000000 2.255304 0.9949255 9.308666e-09 0.0007114611 0.02403599
#> 22: 1.0000000 3.507307 0.9962628 3.190785e-09 0.0015119310 0.02698012
#> 23: 1.0000000 2.193421 0.9909905 6.941415e-08 0.0023665643 0.02577172
#> 24: 1.0000000 2.214172 0.9973294 9.843622e-10 0.0006363358 0.02525688
#> 25: 1.0000000 3.069376 0.9934571 2.265652e-08 0.0013783062 0.02269828
#> 26: 1.0000000 2.535963 0.9960204 3.976072e-09 0.0011374563 0.02402262
#> 27: 0.9838111 0.000100 0.0000000 4.979239e-01 0.0029436207 0.02620160
#> 28: 1.0000000 1.743888 0.9951205 8.115446e-09 0.0027937482 0.02903764
#> 29: 1.0000000 2.039182 0.9729143 3.270314e-06 0.0015619403 0.02427360
#> 30: 1.0000000 2.322658 0.9935786 2.121800e-08 0.0015913349 0.02469797
#> 31: 1.0000000 3.013686 0.9253169 1.138357e-04 0.0040117584 0.02546309
#> 32: 1.0000000 5.000000 0.9442965 4.079327e-05 0.0022454435 0.03159417
#> 33: 1.0000000 5.000000 0.9908466 7.337283e-08 0.0007607914 0.02897195
#> 34: 1.0000000 5.000000 0.8671881 8.537470e-04 0.0032197577 0.02385616
#> 35: 1.0000000 3.372144 0.9971479 1.238942e-09 0.0004630470 0.02145847
#> 36: 1.0000000 3.262119 0.9613882 1.131147e-05 0.0018341727 0.02696312
#> 37: 0.9883815 0.000100 0.0000000 3.003192e-01 0.0034434491 0.02670075
#> 38: 1.0000000 5.000000 0.9917875 5.019502e-08 0.0015741830 0.02216258
#> 39: 1.0000000 2.706836 0.9367858 6.351119e-05 0.0023356139 0.02237141
#> 40: 1.0000000 1.966991 0.9976196 6.580954e-10 0.0026451685 0.03512306
#> 41: 1.0000000 2.270037 0.9991870 1.532058e-11 0.0004309408 0.02583750
#> 42: 1.0000000 2.740291 0.9951004 8.232852e-09 0.0011916253 0.02329129
#> 43: 1.0000000 2.423790 0.9933838 2.355796e-08 0.0039254874 0.02481987
#> 44: 1.0000000 2.161036 0.9941359 1.544166e-08 0.0022236840 0.02302050
#> 45: 1.0000000 2.065713 0.9820954 7.680224e-07 0.0010163372 0.02911082
#> 46: 1.0000000 1.763005 0.9967096 2.043397e-09 0.0014121632 0.02750852
#> 47: 1.0000000 2.755200 0.9964623 2.633342e-09 0.0013740389 0.01788683
#> 48: 1.0000000 2.642410 0.9930514 2.796599e-08 0.0007360079 0.03663836
#> 49: 1.0000000 1.432588 0.9629959 9.747072e-06 0.0024229473 0.01589380
#> 50: 1.0000000 2.287981 0.9995991 1.290124e-12 0.0004814205 0.02605429
#> 51: 1.0000000 2.448673 0.9992976 9.185549e-12 0.0004198723 0.01347179
#> 52: 1.0000000 3.065907 0.9982225 2.367642e-10 0.0023752601 0.02166174
#> 53: 1.0000000 2.776919 0.9969366 1.591078e-09 0.0027166839 0.02379256
#> 54: 1.0000000 2.557727 0.9990998 2.188336e-11 0.0006322521 0.02440520
#> 55: 1.0000000 2.411884 0.9989330 3.968447e-11 0.0015443091 0.02854761
#> 56: 1.0000000 2.003949 0.9940489 1.625854e-08 0.0030714525 0.02768624
#> 57: 1.0000000 2.127642 0.9977338 5.540498e-10 0.0021463145 0.02021322
#> 58: 1.0000000 1.978326 0.9993449 7.196834e-12 0.0008883295 0.02920943
#> 59: 1.0000000 2.736872 0.9994655 3.530406e-12 0.0006289186 0.02246907
#> 60: 1.0000000 2.940905 0.9878645 1.968793e-07 0.0028158117 0.02061972
#> 61: 1.0000000 2.589266 0.9980176 3.468423e-10 0.0024284335 0.02328919
#> 62: 1.0000000 3.002839 0.9978019 4.979588e-10 0.0016845191 0.02727108
#> 63: 1.0000000 2.743208 0.9966324 2.216266e-09 0.0042541545 0.02529924
#> 64: 1.0000000 2.391418 0.9979799 3.705174e-10 0.0027829406 0.02494556
#> 65: 1.0000000 2.475686 0.9965915 2.311928e-09 0.0021365407 0.02789728
#> 66: 1.0000000 1.827993 0.9990550 2.594026e-11 0.0010823145 0.03555896
#> 67: 1.0000000 1.880336 0.9988034 5.926379e-11 0.0011411900 0.02594352
#> 68: 1.0000000 2.213005 0.9983842 1.695655e-10 0.0024649969 0.02468871
#> 69: 1.0000000 1.955457 0.9958787 4.494010e-09 0.0021801892 0.02364677
#> 70: 1.0000000 2.680251 0.9975327 7.461140e-10 0.0015856291 0.02115656
#> 71: 1.0000000 1.932432 0.9991981 1.460497e-11 0.0005404075 0.02845357
#> 72: 1.0000000 1.909176 0.9995183 2.452621e-12 0.0003467009 0.02094491
#> 73: 1.0000000 1.966440 0.9994474 3.967682e-12 0.0004025462 0.03261254
#> 74: 1.0000000 2.324659 0.9966253 2.232695e-09 0.0029765716 0.01687243
#> 75: 1.0000000 2.769539 0.9992905 9.514306e-12 0.0010395275 0.02890447
#> 76: 1.0000000 1.769006 0.9973898 9.085852e-10 0.0012150473 0.02575115
#> 77: 1.0000000 1.937726 0.9990756 2.401496e-11 0.0012638360 0.02401299
#> 78: 1.0000000 1.723879 0.9986513 9.008741e-11 0.0015699934 0.03358047
#> 79: 1.0000000 2.962191 0.9993880 5.670183e-12 0.0010056258 0.02405125
#> 80: 1.0000000 1.984697 0.9960406 3.905880e-09 0.0029102882 0.03048010
#> 81: 1.0000000 1.796886 0.9981400 2.775246e-10 0.0003485312 0.02875185
#> 82: 1.0000000 2.665200 0.9969579 1.552798e-09 0.0009178606 0.02807435
#> 83: 1.0000000 1.837149 0.9963409 2.963407e-09 0.0027780381 0.02321208
#> 84: 1.0000000 2.696824 0.9985293 1.219970e-10 0.0009193400 0.03321846
#> 85: 1.0000000 2.006733 0.9949262 9.303663e-09 0.0010726159 0.02970061
#> 86: 1.0000000 3.117706 0.9948828 9.585348e-09 0.0017207801 0.02613007
#> 87: 1.0000000 3.578535 0.9913418 6.039404e-08 0.0016026034 0.03144202
#> 88: 1.0000000 2.321359 0.9918926 4.798189e-08 0.0037064480 0.02837621
#> 89: 1.0000000 2.023378 0.9948254 9.967103e-09 0.0013976276 0.03160124
#> 90: 1.0000000 1.881323 0.9969943 1.488693e-09 0.0025492991 0.01994518
#> 91: 1.0000000 1.733740 0.9968381 1.777626e-09 0.0009436559 0.02358830
#> 92: 1.0000000 2.086104 0.9970699 1.361674e-09 0.0029342522 0.02633392
#> 93: 1.0000000 2.101833 0.9960998 3.705262e-09 0.0032832350 0.02144606
#> 94: 1.0000000 2.513797 0.9988743 4.786781e-11 0.0013274649 0.03026998
#> 95: 1.0000000 2.099067 0.9968471 1.759891e-09 0.0035472702 0.02618347
#> 96: 1.0000000 3.122947 0.9976141 6.634336e-10 0.0023287486 0.01817215
#> 97: 1.0000000 2.186258 0.9990599 2.547129e-11 0.0011386370 0.02235921
#> 98: 1.0000000 1.998935 0.9961207 3.636093e-09 0.0042739653 0.02298094
#> 99: 1.0000000 2.245643 0.9988156 5.718652e-11 0.0018424204 0.03151223
#> 100: 1.0000000 1.884916 0.9986615 8.773134e-11 0.0018446214 0.03335063
#> E0 h RV RV R2 RV p Value RV Rss RV Sd Avg
#> Fit Type RV RV maxlog10Concentration RV N Conc
#> <char> <num> <int>
#> 1: DRC3pHillFitModelFixS0 1 9
#> 2: DRC3pHillFitModelFixS0 1 9
#> 3: DRC3pHillFitModelFixS0 1 9
#> 4: DRC3pHillFitModelFixS0 1 9
#> 5: DRC3pHillFitModelFixS0 1 9
#> 6: DRC3pHillFitModelFixS0 1 9
#> 7: DRC3pHillFitModelFixS0 1 9
#> 8: DRC3pHillFitModelFixS0 1 9
#> 9: DRC3pHillFitModelFixS0 1 9
#> 10: DRC3pHillFitModelFixS0 1 9
#> 11: DRC3pHillFitModelFixS0 1 9
#> 12: DRC3pHillFitModelFixS0 1 9
#> 13: DRC3pHillFitModelFixS0 1 9
#> 14: DRC3pHillFitModelFixS0 1 9
#> 15: DRC3pHillFitModelFixS0 1 9
#> 16: DRC3pHillFitModelFixS0 1 9
#> 17: DRC3pHillFitModelFixS0 1 9
#> 18: DRC3pHillFitModelFixS0 1 9
#> 19: DRC3pHillFitModelFixS0 1 9
#> 20: DRC3pHillFitModelFixS0 1 9
#> 21: DRC3pHillFitModelFixS0 1 9
#> 22: DRC3pHillFitModelFixS0 1 9
#> 23: DRC3pHillFitModelFixS0 1 9
#> 24: DRC3pHillFitModelFixS0 1 9
#> 25: DRC3pHillFitModelFixS0 1 9
#> 26: DRC3pHillFitModelFixS0 1 9
#> 27: DRCConstantFitResult 1 9
#> 28: DRC3pHillFitModelFixS0 1 9
#> 29: DRC3pHillFitModelFixS0 1 9
#> 30: DRC3pHillFitModelFixS0 1 9
#> 31: DRC3pHillFitModelFixS0 1 9
#> 32: DRC3pHillFitModelFixS0 1 9
#> 33: DRC3pHillFitModelFixS0 1 9
#> 34: DRC3pHillFitModelFixS0 1 9
#> 35: DRC3pHillFitModelFixS0 1 9
#> 36: DRC3pHillFitModelFixS0 1 9
#> 37: DRCConstantFitResult 1 9
#> 38: DRC3pHillFitModelFixS0 1 9
#> 39: DRC3pHillFitModelFixS0 1 9
#> 40: DRC3pHillFitModelFixS0 1 9
#> 41: DRC3pHillFitModelFixS0 1 9
#> 42: DRC3pHillFitModelFixS0 1 9
#> 43: DRC3pHillFitModelFixS0 1 9
#> 44: DRC3pHillFitModelFixS0 1 9
#> 45: DRC3pHillFitModelFixS0 1 9
#> 46: DRC3pHillFitModelFixS0 1 9
#> 47: DRC3pHillFitModelFixS0 1 9
#> 48: DRC3pHillFitModelFixS0 1 9
#> 49: DRC3pHillFitModelFixS0 1 9
#> 50: DRC3pHillFitModelFixS0 1 9
#> 51: DRC3pHillFitModelFixS0 1 9
#> 52: DRC3pHillFitModelFixS0 1 9
#> 53: DRC3pHillFitModelFixS0 1 9
#> 54: DRC3pHillFitModelFixS0 1 9
#> 55: DRC3pHillFitModelFixS0 1 9
#> 56: DRC3pHillFitModelFixS0 1 9
#> 57: DRC3pHillFitModelFixS0 1 9
#> 58: DRC3pHillFitModelFixS0 1 9
#> 59: DRC3pHillFitModelFixS0 1 9
#> 60: DRC3pHillFitModelFixS0 1 9
#> 61: DRC3pHillFitModelFixS0 1 9
#> 62: DRC3pHillFitModelFixS0 1 9
#> 63: DRC3pHillFitModelFixS0 1 9
#> 64: DRC3pHillFitModelFixS0 1 9
#> 65: DRC3pHillFitModelFixS0 1 9
#> 66: DRC3pHillFitModelFixS0 1 9
#> 67: DRC3pHillFitModelFixS0 1 9
#> 68: DRC3pHillFitModelFixS0 1 9
#> 69: DRC3pHillFitModelFixS0 1 9
#> 70: DRC3pHillFitModelFixS0 1 9
#> 71: DRC3pHillFitModelFixS0 1 9
#> 72: DRC3pHillFitModelFixS0 1 9
#> 73: DRC3pHillFitModelFixS0 1 9
#> 74: DRC3pHillFitModelFixS0 1 9
#> 75: DRC3pHillFitModelFixS0 1 9
#> 76: DRC3pHillFitModelFixS0 1 9
#> 77: DRC3pHillFitModelFixS0 1 9
#> 78: DRC3pHillFitModelFixS0 1 9
#> 79: DRC3pHillFitModelFixS0 1 9
#> 80: DRC3pHillFitModelFixS0 1 9
#> 81: DRC3pHillFitModelFixS0 1 9
#> 82: DRC3pHillFitModelFixS0 1 9
#> 83: DRC3pHillFitModelFixS0 1 9
#> 84: DRC3pHillFitModelFixS0 1 9
#> 85: DRC3pHillFitModelFixS0 1 9
#> 86: DRC3pHillFitModelFixS0 1 9
#> 87: DRC3pHillFitModelFixS0 1 9
#> 88: DRC3pHillFitModelFixS0 1 9
#> 89: DRC3pHillFitModelFixS0 1 9
#> 90: DRC3pHillFitModelFixS0 1 9
#> 91: DRC3pHillFitModelFixS0 1 9
#> 92: DRC3pHillFitModelFixS0 1 9
#> 93: DRC3pHillFitModelFixS0 1 9
#> 94: DRC3pHillFitModelFixS0 1 9
#> 95: DRC3pHillFitModelFixS0 1 9
#> 96: DRC3pHillFitModelFixS0 1 9
#> 97: DRC3pHillFitModelFixS0 1 9
#> 98: DRC3pHillFitModelFixS0 1 9
#> 99: DRC3pHillFitModelFixS0 1 9
#> 100: DRC3pHillFitModelFixS0 1 9
#> Fit Type RV RV maxlog10Concentration RV N Conc
convert_se_assay_to_custom_dt(se, "Metrics", output_table = "Metrics_initial")
#> rId cId x_mean
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.4466890
#> 2: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.4729298
#> 3: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.3939872
#> 4: G00003_drug_003_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.3932199
#> 5: G00004_drug_004_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.7989283
#> ---
#> 196: G00009_drug_009_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.0774842
#> 197: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.5769999
#> 198: G00010_drug_010_moa_A_72 CL00020_cellline_KB_tissue_z_62 0.1991504
#> 199: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 0.4117805
#> 200: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 -0.1148134
#> x_AOC x_AOC_range xc50 x_max ec50 x_inf
#> <num> <num> <num> <num> <num> <num>
#> 1: 0.5533110 0.6277120 0.007253171 0.32793333 0.003795893 0.34682665
#> 2: 0.5270702 0.6048472 0.008956223 0.33660000 0.004512560 0.36516781
#> 3: 0.6060128 0.6954994 0.005655581 0.27413333 0.003962986 0.28319787
#> 4: 0.6067801 0.7027714 0.006591468 0.25136667 0.004714084 0.26639679
#> 5: 0.2010717 0.2385432 Inf 0.70636667 0.016546380 0.71001484
#> ---
#> 196: 0.9225158 1.0742560 0.026077313 -0.49686667 0.037516853 -0.52393526
#> 197: 0.4230001 0.4723104 0.150209032 0.07513333 0.137152296 0.09235428
#> 198: 0.8008496 0.8915995 0.096729600 -0.78626667 0.146270629 -0.74430401
#> 199: 0.5882195 0.6900581 0.027440547 0.08603333 0.024485958 0.09662172
#> 200: 1.1148134 1.3059605 0.016239553 -0.76026667 0.026434030 -0.73401896
#> x_0 h r2 p_value rss x_sd_avg
#> <num> <num> <num> <num> <num> <num>
#> 1: 1 1.827031 0.9924695 3.705769e-08 0.002778822 0.02424423
#> 2: 1 1.911901 0.9884406 1.660656e-07 0.004530345 0.03203268
#> 3: 1 2.349599 0.9958511 4.600131e-09 0.002182340 0.02195104
#> 4: 1 2.270093 0.9905292 8.267143e-08 0.005670066 0.03075240
#> 5: 1 3.159939 0.9918874 4.809026e-08 0.001162341 0.02315049
#> ---
#> 196: 1 1.970723 0.9955609 5.828304e-09 0.017400921 0.04602459
#> 197: 1 2.245643 0.9988156 5.718652e-11 0.001842420 0.03151223
#> 198: 1 2.204685 0.9985705 1.104466e-10 0.008161064 0.06333498
#> 199: 1 1.884916 0.9986615 8.773134e-11 0.001844621 0.03335063
#> 200: 1 1.854308 0.9987249 7.403286e-11 0.006484241 0.07007818
#> fit_type maxlog10Concentration N_conc normalization_type
#> <char> <num> <int> <char>
#> 1: DRC3pHillFitModelFixS0 1 9 RV
#> 2: DRC3pHillFitModelFixS0 1 9 GR
#> 3: DRC3pHillFitModelFixS0 1 9 RV
#> 4: DRC3pHillFitModelFixS0 1 9 GR
#> 5: DRC3pHillFitModelFixS0 1 9 RV
#> ---
#> 196: DRC3pHillFitModelFixS0 1 9 GR
#> 197: DRC3pHillFitModelFixS0 1 9 RV
#> 198: DRC3pHillFitModelFixS0 1 9 GR
#> 199: DRC3pHillFitModelFixS0 1 9 RV
#> 200: DRC3pHillFitModelFixS0 1 9 GR
#> fit_source Gnumber DrugName drug_moa Duration clid CellLineName
#> <char> <char> <char> <char> <num> <char> <char>
#> 1: gDR G00002 drug_002 moa_A 72 CL00011 cellline_BA
#> 2: gDR G00002 drug_002 moa_A 72 CL00011 cellline_BA
#> 3: gDR G00003 drug_003 moa_A 72 CL00011 cellline_BA
#> 4: gDR G00003 drug_003 moa_A 72 CL00011 cellline_BA
#> 5: gDR G00004 drug_004 moa_A 72 CL00011 cellline_BA
#> ---
#> 196: gDR G00009 drug_009 moa_A 72 CL00020 cellline_KB
#> 197: gDR G00010 drug_010 moa_A 72 CL00020 cellline_KB
#> 198: gDR G00010 drug_010 moa_A 72 CL00020 cellline_KB
#> 199: gDR G00011 drug_011 moa_B 72 CL00020 cellline_KB
#> 200: gDR G00011 drug_011 moa_B 72 CL00020 cellline_KB
#> Tissue ReferenceDivisionTime
#> <char> <num>
#> 1: tissue_x 26
#> 2: tissue_x 26
#> 3: tissue_x 26
#> 4: tissue_x 26
#> 5: tissue_x 26
#> ---
#> 196: tissue_z 62
#> 197: tissue_z 62
#> 198: tissue_z 62
#> 199: tissue_z 62
#> 200: tissue_z 62
convert_se_assay_to_custom_dt(se, "Averaged")
#> Key: <r Id, c Id, Concentration, Gnumber, Drug Name, Drug MOA, Duration, Clid, Cell Line Name, Tissue, Reference Division Time>
#> r Id c Id Concentration
#> <char> <char> <num>
#> 1: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.001000000
#> 2: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.003162278
#> 3: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.010000000
#> 4: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.031622777
#> 5: G00002_drug_002_moa_A_72 CL00011_cellline_BA_tissue_x_26 0.100000000
#> ---
#> 896: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 0.100000000
#> 897: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 0.316227766
#> 898: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 1.000000000
#> 899: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 3.162277660
#> 900: G00011_drug_011_moa_B_72 CL00020_cellline_KB_tissue_z_62 10.000000000
#> Gnumber Drug Name Drug MOA Duration Clid Cell Line Name Tissue
#> <char> <char> <char> <num> <char> <char> <char>
#> 1: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 2: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 3: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 4: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> 5: G00002 drug_002 moa_A 72 CL00011 cellline_BA tissue_x
#> ---
#> 896: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 897: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 898: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 899: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> 900: G00011 drug_011 moa_B 72 CL00020 cellline_KB tissue_z
#> Reference Division Time Relative Viability GR value
#> <num> <num> <num>
#> 1: 26 0.92496667 0.9444333
#> 2: 26 0.73910000 0.7931000
#> 3: 26 0.43593333 0.4813333
#> 4: 26 0.33626667 0.3482000
#> 5: 26 0.34670000 0.3634000
#> ---
#> 896: 62 0.15343333 -0.6027000
#> 897: 62 0.10486667 -0.7146000
#> 898: 62 0.11136667 -0.6985000
#> 899: 62 0.08603333 -0.7602667
#> 900: 62 0.09353333 -0.7411000
#> Std Relative Viability Std GR value
#> <num> <num>
#> 1: 0.01066130 0.008058743
#> 2: 0.01484621 0.013021521
#> 3: 0.03071503 0.038118412
#> 4: 0.03491938 0.050414581
#> 5: 0.03191175 0.045352067
#> ---
#> 896: 0.03347721 0.075558785
#> 897: 0.03833593 0.089379024
#> 898: 0.02465651 0.058096385
#> 899: 0.04227556 0.100949212
#> 900: 0.02869866 0.069724529